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Plasma concentration and clinical effects of perampanel—The Kork experience

Autor: Uta Jürges, Bernhard J. Steinhoff, Elisabeth Hübers, Christoph Kurth

Publikováno v: Seizure. 67:18-22

Purpose To investigate the correlation between steady-state plasma concentrations of perampanel (PER) with efficacy and tolerability in adult patients with difficult-to-treat epilepsy. Methods PER plasma concentrations were assessed at steady-state c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ff3c35385a8ca8b5798540ed74530d
https://doi.org/10.1016/j.seizure.2019.02.022

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Erratum to 'Plasma concentration and clinical effects of perampanel-The Kork experience' [Seizure, 67 (April) (2019), 18-22]

Autor: Uta Jürges, Elisabeth Hübers, Christoph Kurth, Bernhard J. Steinhoff

Publikováno v: Seizure. 67

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4c63e065ef97d1d380c5eda60f2077
https://pubmed.ncbi.nlm.nih.gov/30852267

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Unterschiedlicher Effekt von Monotherapien mit Carbamazepin, Oxcarbazepin und Lamotrigin auf klinisch relevante Laborparameter

Autor: Uta Jürges, Anke M. Staack, Christoph Kurth, Bernhard J. Steinhoff, Christoph Winkler

Publikováno v: Zeitschrift für Epileptologie. 20:135-142

Oxcarbazepin (OXC) wird im Vergleich zu Carbamazepin (CBZ) aufgrund der geringeren Enzyminduktion ein vorteilhaftes Profil zugeschrieben. Entsprechend wurde in der Literatur uber eine Normalisierung der Gamma-Glutamyl-Transferase (GGT) nach Ersatz vo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::431c15756b4668c3649cc0da6b73d7ed
https://doi.org/10.1007/s10309-007-0260-2

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Add-on lacosamide: a retrospective study on the relationship between serum concentration, dosage, and adverse events

Autor: Uta Jürges, Ilona Wisniewski, Barbara Hillenbrand, Bernhard J. Steinhoff

Publikováno v: Epilepsybehavior : EB. 22(3)

We performed a retrospective study in patients with poorly controlled epilepsy treated with add-on lacosamide (LCM) to investigate the relationship of LCM-related adverse events with LCM serum concentration and weight-dependent dosage. We collected s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e6a5cbed973327040f1f3ac1f08e08
https://pubmed.ncbi.nlm.nih.gov/21962950

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Comparison of total and free phenytoin serum concentrations measured by high-performance liquid chromatography and standard TDx assay: implications for the prediction of free phenytoin serum concentrations

Autor: Volker Blankenhorn, Bernard Rambeck, Uta Jürges, Uwe Jürgens, Theodor W. May

Publikováno v: Therapeutic drug monitoring. 20(6)

The free fraction of phenytoin (PHT) in serum increases considerably in combination with valproic acid (VPA), depending on the VPA concentration. Equations to predict the free PHT concentration (PHTf) from the total PHT concentration (PHTt) and from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38332fbf7b716ab84356b8dbf975a32c
https://pubmed.ncbi.nlm.nih.gov/9853976

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