Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Uta Binzen"'
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Pain is the vital sense preventing tissue damage by harmful noxious stimuli. The capsaicin receptor TRPV1 is activated by noxious temperatures, however, acute heat pain is only marginally affected in mice after TRPV1 knockout but
Externí odkaz:
https://doaj.org/article/413bac2222ba4abaa0b65087b91a38fd
Autor:
Charalambos Tsagogiorgas, Johannes Wedel, Maximilia Hottenrott, Michael O Schneider, Uta Binzen, Wolfgang Greffrath, Rolf-Detlef Treede, Bastian Theisinger, Sonja Theisinger, Rüdiger Waldherr, Bernhard K Krämer, Manfred Thiel, Peter Schnuelle, Benito A Yard, Simone Hoeger
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43525 (2012)
Since stimulation of transient receptor potential channels of the vanilloid receptor subtype 1 (TRPV1) mitigates acute kidney injury (AKI) and endogenous N-acyl dopamine derivatives are able to activate TRPV1, we tested if synthetic N-octanoyl-dopami
Externí odkaz:
https://doaj.org/article/b3fd39bb2d0146e4bf4a838d722eda7d
Autor:
Charalambos Tsagogiorgas, Johannes Wedel, Maximilia Hottenrott, Michael O. Schneider, Uta Binzen, Wolfgang Greffrath, Rolf-Detlef Treede, Bastian Theisinger, Sonja Theisinger, Rüdiger Waldherr, Bernhard K. Krämer, Manfred Thiel, Peter Schnuelle, Benito A. Yard, Simone Hoeger
Publikováno v:
PLoS ONE, Vol 7, Iss 8 (2012)
Externí odkaz:
https://doaj.org/article/afe94096aae040e6a556962d74265858
Publikováno v:
Pflugers Archiv : European journal of physiology. 474(9)
We studied the efficacy of a near-infrared laser (1475 nm) to activate rat dorsal root ganglion (DRG) neurons with short punctate radiant heat pulses (55 µm diameter) and investigated temporal and spatial summation properties for the transduction pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4861785e1ca564e17e94a7f8b1afa050
https://pubmed.ncbi.nlm.nih.gov/35867188
https://pubmed.ncbi.nlm.nih.gov/35867188
Autor:
Carmen Wängler, Wolfgang Greffrath, Björn Wängler, Steffen Roth, Martin C. Harmsen, Prama Pallavi, Bernhard K. Krämer, Bastian Theisinger, Ralf Loesel, Marc Pretze, Benito A. Yard, Sarah Klotz, Yingchun Li, Rolf-Detlef Treede, Björn B. Hofmann, Eleni Stamellou, Mathias Hafner, Uta Binzen, Julio Caballero, Anna-Isabelle Kälsch, Handan Moerz
Publikováno v:
Journal of Medicinal Chemistry, 61(7), 3126-3137. AMER CHEMICAL SOC
We studied the chemical entities within N-octanoyl dopamine (NOD) responsible for the activation of transient-receptor-potential channels of the vanilloid-receptor subtype 1 (TRPV1) and inhibition of inflammation. The potency of NOD in activating TRP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa5ae9b6ceec784e087ab8601afec88
https://doi.org/10.1021/acs.jmedchem.8b00156
https://doi.org/10.1021/acs.jmedchem.8b00156
Autor:
Marc Pretze, Martin C. Harmsen, Julio Caballero, Björn Wängler, Uta Binzen, Rolf-Detlef Treede, Mareike Roscher, Wolfgang Greffrath, Prama Pallavi, Benito A. Yard, Sarah Klotz, Carmen Wängler, Mathias Hafner
Publikováno v:
Journal of Medicinal Chemistry, 59(21), 9855-9865. AMER CHEMICAL SOC
To mitigate pretransplantation injury in organs of potential donors, N-octanoyl dopamine (NOD) treatment might be considered as it does not affect hemodynamic parameters in braindead (BD) donors. To better assess optimal NOD concentrations for donor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c2b0a4dac5c7ae930a1f2fc9a46614
https://doi.org/10.1021/acs.jmedchem.6b01191
https://doi.org/10.1021/acs.jmedchem.6b01191
Publikováno v:
Der Schmerz. 29:223-226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcfc17dd5a69562b71b25f88ccb34f80
https://doi.org/10.1007/s00482-014-1492-5
https://doi.org/10.1007/s00482-014-1492-5
Autor:
Rolf-Detlef Treede, Handan Mörz, Peter Bugert, Angelika Schedel, Wolfgang Greffrath, Kristina Maurer, Uta Binzen
Publikováno v:
Neuroscience Letters. 563:101-106
Since many years acetylsalicylic acid (ASA) is known for its antithrombotic, antiphlogistic and analgesic effects caused by irreversible acetylation of cyclooxygenase. ASA also inhibits capsaicin- and heat-induced responses in cultured dorsal root ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91c71c26f86668b2c811aa54bcdf23f
https://doi.org/10.1016/j.neulet.2014.01.050
https://doi.org/10.1016/j.neulet.2014.01.050
Autor:
Wolfgang Greffrath, Uta Binzen, Simone Hoeger, Martin C. Harmsen, Frank G. Zöllner, Charalambos Tsagogiorgas, Jakob Walter, Bernhard K. Krämer, Mathias Hafner, Rolf-Detlef Treede, Benito A. Yard, Sarah Klotz, F. Zimmer, Prama Pallavi
Publikováno v:
Nephrology, Dialysis, Transplantation, 31(4), 564-573. Oxford University Press
N-octanoyl dopamine (NOD) treatment improves renal function when applied to brain dead donors and in the setting of warm ischaemia-induced acute kidney injury (AKI). Because it also activates transient receptor potential vanilloid type 1 (TRPV1) chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b0bf5456b976f91e7edcf3a19437b2
https://pubmed.ncbi.nlm.nih.gov/26464459
https://pubmed.ncbi.nlm.nih.gov/26464459
Publikováno v:
NeuroReport. 14:2251-2255
Expression of the heat sensitive cation channels TRPV1 and TRPV2 was investigated by immunofluorescence in rat dorsal root ganglion (DRG) neurons. TRPV1-positive neurons were more frequent and had smaller diameters than TRPV2-positive neurons (35.7%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76ca13633b58927f031dc7f2cccc012
https://doi.org/10.1097/00001756-200312020-00023
https://doi.org/10.1097/00001756-200312020-00023