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Regulation of plasmid R1 replication: PcnB and RNase E expedite the decay of the antisense RNA, CopA
Publikováno v:
Molecular Microbiology. 26:493-504
The replication frequency of plasmid R1 is controlled by an unstable antisense RNA, CopA, which, by binding to its complementary target, blocks translation of the replication rate-limiting protein RepA. Since the degree of inhibition is directly corr
Publikováno v:
Microbiology (Reading, England). 145
RNAI is a short RNA, 108 nt in length, which regulates the replication of the plasmid ColE1. RNAI turns over rapidly, enabling plasmid replication rate to respond quickly to changes in plasmid copy number. Because RNAI is produced in abundance, is ea
Publikováno v:
Molecular microbiology. 9(6)
The replication of ColE1-related plasmids is controlled by an unstable antisense RNA, RNAI, which can interfere with the successful processing of the RNAII primer of replication. We show here that a host protein, PcnB, supports replication by promoti