Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Uta B. Schambra"'
Publikováno v:
Neurotoxicology and Teratology. 51:1-11
Human and animal studies show significant delays in neurobehavioral development in offspring after prolonged prenatal exposure to moderate and high ethanol doses resulting in high blood alcohol concentration (BECs). However, none have investigated th
Publikováno v:
Neurotoxicology and teratology. 62
Debate continues on the merits of strictly limiting alcohol consumption during all of pregnancy, and whether "safe" consumption levels and/or times exist. Only a relatively few experimental studies have been conducted that limit the timing of exposur
Publikováno v:
Neurotoxicology and teratology. 57
In a previous study we used a mouse model for ethanol exposure during gastrulation or neurulation to investigate the effects of modest and occasional human drinking during the 3rd or 4th week of pregnancy (Schambra et al., 2015). Pregnant C57Bl/6J mi
Autor:
Stella O. Page, Uta B. Schambra, Charlene D. Richardson, Robert T. Fremeau, Debra A. Schwinn, Katrina H. Wilson, Mark Stafford Smith
Publikováno v:
Brain Research Protocols. 1:175-185
In situ hybridization is used for detection of RNA expression when conservation of tissue architecture is important. Most in situ hybridization protocols are written for tissues from animals (i.e., rat) which can be harvested and preserved rapidly. I
Autor:
Mark Stafford Smith, Uta B. Schambra, Katrina H. Wilson, Stella O. Page, Christine Hulette, Alan R. Light, Debra A. Schwinn
Publikováno v:
Molecular Brain Research. 34:109-117
alpha 2-Adrenergic receptor (AR) subtype mRNA (alpha 2a, alpha 2b, alpha 2c) neuronal localization in human spinal cord has not been described. We therefore performed in situ hybridization to identify cell bodies at four levels of human spinal cord (
Autor:
Marc G. Caron, Robert T. Fremeau, Uta B. Schambra, M.G. Fornaretto, George R. Breese, Gary E. Duncan
Publikováno v:
Neuroscience. 62:65-85
The prenatal and postnatal ontogeny of D 1A and D 2 dopamine receptors was assessed by in situ hybridization of messenger RNAs encoding the receptors and by radioligand binding autoradiography. On gestational day 14, signals for D 1A and D 2 dopamine
Autor:
Diane M. Hayden-Hixson, Mika Scheinin, Robert T. Fremeau, Robert J. Lefkowitz, Marc G. Caron, Uta B. Schambra, Jon W. Lomasney
Publikováno v:
Molecular Brain Research. 21:133-149
alpha 2-Adrenergic receptors in brain are important presynaptic modulators of central noradrenergic function (autoreceptors) and postsynaptic mediators of many of the widespread effects of catecholamines and related drugs. alpha 2-Adrenergic agonists
Publikováno v:
Journal of Chemical Neuroanatomy. 5:299-310
Department of Anatomy and Cell Biology, *Brain and Development Research Center, and tDepartment of Physiology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA INTRODUCTION The receptors for serotonin (5-HT) are distributed
Publikováno v:
Experimental Neurology. 115:429-435
Publikováno v:
International Journal of Developmental Neuroscience. 8:507-517
Acute maternal ethanol administration to C57B1/6J mice on gestational day 7 (GD7) results in facial and brain abnormalities similar to those reported in human fetal alcohol syndrome (FAS). Using this model, we assessed the damage to brain structures