Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Uta B, Hofmann"'
Publikováno v:
Clinical Cancer Research. 15:324-329
Purpose: Recently, gene amplification and overexpression of KIT as well as activating mutations in the KIT gene have been described to occur in certain subsets of melanoma. These findings suggest KIT as a potential target for therapy with imatinib me
Publikováno v:
International Journal of Dermatology. 44:736-742
Background Recently, it has been shown that UVB phototherapy may be more effective than UVA in the treatment of vitiligo. Currently, however, no studies have compared the efficacy of UVB311 nm and broad-band UVB therapy. Calcipotriol has recently bee
Publikováno v:
Archives of Dermatological Research. 297:154-160
Matrix metalloproteinases (MMPs) are essential for tumor progression, invasion and metastases formation. Expression of these proteinases is not only restricted to the tumor cells themselves, but also is found in normal stromal cells. Moreover, immuno
Publikováno v:
Biochimie. 87:307-314
Cutaneous melanomas are notorious for their tendency to metastasize. Essential steps in this process are the degradation of basement membranes and remodeling of the extracellular matrix (ECM) by proteolytic enzymes such as matrix metalloproteinases (
Publikováno v:
British Journal of Dermatology. 148:779-783
SummaryBackground Narrow-band ultraviolet (UV) B (311 nm) phototherapy is an effective treatment for psoriasis. In order to reduce cumulative UV doses and to enhance clearance of psoriasis plaques, combination therapies with topical agents such as di
Publikováno v:
Der Hautarzt. 53:587-595
Das Melanom der Haut ist ein invasiv wachsender und fruhzeitig metastasierender Tumor. Fur die Ablosung einzelner Melanomzellen vom Primartumor, Migration dieser Zellen durch Basalmembranen, Extravasation aus Blut- und Lymphgefasen bis hin zur Bildun
Publikováno v:
Der Hautarzt. 53:253-257
Die Fanconi-Anamie ist ein seltenes, autosomal-rezessiv vererbtes Fehlbildungssyndrom mit variabler klinischer Expression. Bisher konnten 8 verschiedene genetische Komplementationsgruppen charakterisiert werden; fur 4 von ihnen wurde das Gen bereits
Publikováno v:
Der Hautarzt. 52:1058-1061
Autor:
St. Münnich, St. Rickert, Uta B. Hofmann, Eva-B. Bröcker, J. C. Becker, Eckhart Kämpgen, Patrick Terheyden
Publikováno v:
Der Hautarzt. 52:803-806
A 59-year-old patient presented with metastatic uveal melanoma that developed in a nevus of Ota. The nevus of Ota or oculodermal melanocytosis contains an increased number of dermal melanocytes in the distribution of the ophthalmic and maxillary divi
Autor:
G.N.P. van Muijen, Jürgen C. Becker, Johan R. Westphal, Dirk J. Ruiter, Albert J.W. Zendman, Uta B. Hofmann
Publikováno v:
The Journal of Pathology. 191:245-256
Matrix metalloproteinases (MMPs) and their specific tissue inhibitors (TIMPs) play an important role in cancer cell invasion and metastasis. Recently, it was shown that the presence of activated MMP-2 correlates with melanoma progression in vitro. Th