Rapid turnover of Plasmodium falciparum var gene transcripts and genotypes during natural non-symptomatic infections Rápida mudança de transcritos var e de génotipos de Plasmodium falciparum em infecções assintomáticas naturalmente adquiridas

Autor: Gerhard Wunderlich, Fabiana P. Alves, Uta Gölnitz, Mauro S. Tada, Erney F.P. de Camargo, Luiz H. Pereira-da-Silva

Publikováno v: Revista do Instituto de Medicina Tropical de São Paulo, Vol 47, Iss 4, Pp 195-201 (2005)

The var genes of Plasmodium falciparum code for the antigenically variant erythrocyte membrane proteins 1 (PfEMP1), a major factor for cytoadherence and immune escape of the parasite. Herein, we analyzed the var gene transcript turnover in two ongoin

Externí odkaz: https://doaj.org/article/7fc2e6d5dcdf45d0a3ba5734186056e4

Rapid turnover of Plasmodium falciparum var gene transcripts and genotypes during natural non-symptomatic infections

Autor: Luiz Hildebrando Pereira-da-Silva, Erney P. Camargo, Gerhard Wunderlich, Uta Gölnitz, Mauro Shugiro Tada, Fabiana Alves

Publikováno v: Revista do Instituto de Medicina Tropical de São Paulo; Vol. 47 No. 4 (2005); 195-201
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 47 Núm. 4 (2005); 195-201
Revista do Instituto de Medicina Tropical de São Paulo; v. 47 n. 4 (2005); 195-201
Revista do Instituto de Medicina Tropical de São Paulo
Instituto de Medicina Tropical (IMT)
instacron:IMT
Revista do Instituto de Medicina Tropical de São Paulo, Volume: 47, Issue: 4, Pages: 195-201, Published: AUG 2005

Os genes var de Plasmodium falciparum codificam as proteínas variantes da superfície do eritrócito infectado (PfEMP1). Neste estudo examinamos a mudança de transcritos destes genes var em duas infecções assintomáticas durante um curto prazo e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6dad24ae20e574ba901e68860553a3e
https://doi.org/10.1590/s0036-46652005000400004

Targeted next generation sequencing in SPAST-negative hereditary spastic paraplegia

Autor: Arndt Rolfs, Himesha Vandebona, Karl Ng, Christine Klein, David M. Sharpe, Viatcheslav Saviouk, Carolyn M. Sue, Nicholas F. Blair, Christina Liang, Anne Grünewald, Uta Gölnitz, Kishore R. Kumar

Publikováno v: Journal of neurology. 260(10)

Molecular characterization is important for an accurate diagnosis in hereditary spastic paraplegia (HSP). Mutations in the gene SPAST (SPG4) are the most common cause of autosomal dominant forms. We performed targeted next generation sequencing (NGS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7161ad8191360b40a93f49191e34756
https://pubmed.ncbi.nlm.nih.gov/23812641

Newborn Screening for Lysosomal Storage Disorders in Hungary

Autor: Anne-Katrin Giese, Michael Klingenhäger, Elisa Legnini, Sándor Túri, Olaf Bodamer, Uta Gölnitz, Adolf Mühl, Jan Lukas, Arndt Rolfs, Judit Wittmann, Gyula Wittmann, Eszter Karg

Publikováno v: JIMD Reports ISBN: 9783642281280

Even though lysosomal storage disorders (LSDs) are considered to be orphan diseases, they pose a highly relevant cause for morbidity and mortality as their cumulative prevalence is estimated to be 1:4,000. This is especially important as treatment in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f95b52708f25ab534140f03cd2a298
https://europepmc.org/articles/PMC3565645/

Replicon system for Lassa virus

Autor: Stefanie Müller, Stephan Günther, Beate Becker-Ziaja, Meike Hass, Uta Gölnitz

Publikováno v: Journal of virology. 78(24)

Lassa virus is endemic to West Africa and causes hemorrhagic fever in humans. To facilitate the functional analysis of this virus, a replicon system was developed based on Lassa virus strain AV. Genomic and antigenomic minigenomes (MG) were construct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ee042d17ab8d6311c1b44953e1b070
https://pubmed.ncbi.nlm.nih.gov/15564487