Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Uta, Funke"'
Autor:
Lisette, Meijer, Kinga P, Böszörményi, Jaco, Bakker, Gerrit, Koopman, Petra, Mooij, Dagmar, Verel, Zahra, Fagrouch, Babs E, Verstrepen, Uta, Funke, Martien P J, Mooijer, Jan A M, Langermans, Ernst J, Verschoor, Albert D, Windhorst, Marieke A, Stammes
Publikováno v:
Nuclear medicine and biology.
The aim of this study was to investigate the application of [Four experimentally SARS-CoV-2 infected rhesus monkeys were followed for seven weeks post infection (pi) with a weekly PET-CT using [All animals were positive for SARS-CoV-2 in both the swa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37fb743c27de68b8235df80500ff29db
https://pubmed.ncbi.nlm.nih.gov/35660200
https://pubmed.ncbi.nlm.nih.gov/35660200
Autor:
Reik Löser, Steffen Fischer, Achim Hiller, Martin Köckerling, Uta Funke, Aurélie Maisonial, Peter Brust, Jörg Steinbach
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 1002-1011 (2013)
3-[18F]Fluoropropanesulfonyl chloride, a recently proposed prosthetic agent for fluorine-18 labelling, was prepared in a two-step radiosynthesis via 3-[18F]fluoropropyl thiocyanate as an intermediate. Two benzenesulfonate-based radiolabelling precurs
Externí odkaz:
https://doaj.org/article/74f3177d65cb44938da46750578487e9
Autor:
Detlef Briel, Peter Brust, Achim Hiller, Gregor Schwan, Aurélie Maisonial, Matthias Scheunemann, Steffen Fischer, Winnie Deuther-Conrad, Uta Funke
Publikováno v:
Pharmaceuticals, Vol 5, Iss 2, Pp 169-188 (2012)
Phosphodiesterase 10A (PDE10A) is a key enzyme of intracellular signal transduction which is involved in the regulation of neurotransmission. The molecular imaging of PDE10A by PET is expected to allow a better understanding of physiological and path
Externí odkaz:
https://doaj.org/article/7a428058c19f456db8b84413d8811248
Autor:
Alessandro Villa, Johnny Vercouillie, Bieneke Janssen, Danielle J. Vugts, Giovanna Pepe, Adriana Maggi, Albert D. Windhorst, Frédéric Dollé, Alexandra Winkeler, Luigi Sironi, Jordi Pedragosa, Dieter Ory, Paolo Gelosa, Annelaure Damont, Elisabetta Vegeto, Benoit Jego, Anna M. Planas, Wissam Beaino, Sandra Laner-Plamberger, Bastian Zinnhardt, Palle Christophersen, Ludwig Aigner, Olof Solin, Uta Funke, Barbara Klein, Linda V. Blomster, Andreas H. Jacobs
Publikováno v:
Theranostics
Villa, A, Klein, B, Janssen, B, Pedragosa, J, Pepe, G, Zinnhardt, B, Vugts, D J, Gelosa, P, Sironi, L, Beaino, W, Damont, A, Dollé, F, Jego, B, Winkeler, A, Ory, D, Solin, O, Vercouillie, J, Funke, U, Laner-Plamberger, S, Blomster, L V, Christophersen, P, Vegeto, E, Aigner, L, Jacobs, A, Planas, A M, Maggi, A & Windhorst, A D 2018, ' Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state ', Theranostics, vol. 8, no. 19, pp. 5400-5418 . https://doi.org/10.7150/thno.25572
Theranostics, 8(19), 5400-5418. Ivyspring International Publisher
Villa, A, Klein, B, Janssen, B, Pedragosa, J, Pepe, G, Zinnhardt, B, Vugts, D J, Gelosa, P, Sironi, L, Beaino, W, Damont, A, Dollé, F, Jego, B, Winkeler, A, Ory, D, Solin, O, Vercouillie, J, Funke, U, Laner-Plamberger, S, Blomster, L V, Christophersen, P, Vegeto, E, Aigner, L, Jacobs, A, Planas, A M, Maggi, A & Windhorst, A D 2018, ' Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state ', Theranostics, vol. 8, no. 19, pp. 5400-5418 . https://doi.org/10.7150/thno.25572
Theranostics, 8(19), 5400-5418. Ivyspring International Publisher
Microglia are potential targets for therapeutic intervention in neurological and neurodegenerative diseases affecting the central nervous system. In order to assess the efficacy of therapies aimed to reduce the tissue damaging activities of microglia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40921a2f7da9ba0fd0e440055c2e505c
https://doi.org/10.7150/thno.25572
https://doi.org/10.7150/thno.25572
Publikováno v:
ChemCatChem. 8:3692-3700
Carbon dioxide (CO2) as a synthon in organic transformations is very useful, especially when combined with transition metal catalysts. CO2 insertion on carbon(Aryl)-metal bonds are an elegant way to construct carbon-carbon bonds. A limited number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177f29b47268cf3ce636d93c64b48ee8
https://doi.org/10.1002/cctc.201600943
https://doi.org/10.1002/cctc.201600943
Autor:
Perry S. Kruijer, Adriaan A. Lammertsma, Danielle J. Vugts, Albert D. Windhorst, Bieneke Janssen, Uta Funke, Ger T. Molenaar, Bart N.M. van Berckel
Publikováno v:
Janssen, B, Vugts, D J, Funke, U, Molenaar, G T, Kruijer, P S, van Berckel, B N M, Lammertsma, A A & Windhorst, A D 2016, ' Imaging of neuroinflammation in Alzheimer's disease, multiple sclerosis and stroke: Recent developments in positron emission tomography ', Biochimica et Biophysica Acta. Molecular Basis of Disease, vol. 1862, no. 3, pp. 425-441 . https://doi.org/10.1016/j.bbadis.2015.11.011
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1862(3), 425-441. Elsevier
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1862(3), 425-441. Elsevier
Neuroinflammation is thought to play a pivotal role in many diseases affecting the brain, including Alzheimer's disease, multiple sclerosis and stroke. Neuroinflammation is characterised predominantly by microglial activation, which can be visualised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3350e029d36c9e5805bcc3c6b0eadb80
Autor:
Jeroen J.M. Hoozemans, Rostislav V Shevchenko, Ger T. Molenaar, Veerle Baekelandt, Sylvie Chalon, Aurélie Doméné, Guy Bormans, Adriana Maggi, Wissam Beaino, Michael Kassiou, Adriaan A. Lammertsma, Uta Funke, Shane M. Wilkinson, Robert C. Schuit, Alessandro Villa, Esther J.M. Kooijman, Johan van den Hoek, Bieneke Janssen, Anke Van der Perren, Mansoor Chishty, Danielle J. Vugts, Albert D. Windhorst, Dieter Ory
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Janssen, B, Vugts, D J, Wilkinson, S M, Ory, D, Chalon, S, Hoozemans, J J M, Schuit, R C, Beaino, W, Kooijman, E J M, Van Den Hoek, J, Chishty, M, Doméné, A, Van Der Perren, A, Villa, A, Maggi, A, Molenaar, G T, Funke, U, Shevchenko, R V, Baekelandt, V, Bormans, G, Lammertsma, A A, Kassiou, M & Windhorst, A D 2018, ' Identification of the allosteric P2X 7 receptor antagonist [ 11 C]SMW139 as a PET tracer of microglial activation ', Scientific Reports, vol. 8, no. 1, 6580 . https://doi.org/10.1038/s41598-018-24814-0
Scientific Reports, 8(1):6580. Nature Publishing Group
Janssen, B, Vugts, D J, Wilkinson, S M, Ory, D, Chalon, S, Hoozemans, J J M, Schuit, R C, Beaino, W, Kooijman, E J M, Van Den Hoek, J, Chishty, M, Doméné, A, Van Der Perren, A, Villa, A, Maggi, A, Molenaar, G T, Funke, U, Shevchenko, R V, Baekelandt, V, Bormans, G, Lammertsma, A A, Kassiou, M & Windhorst, A D 2018, ' Identification of the allosteric P2X 7 receptor antagonist [ 11 C]SMW139 as a PET tracer of microglial activation ', Scientific Reports, vol. 8, no. 1, 6580 . https://doi.org/10.1038/s41598-018-24814-0
Scientific Reports, 8(1):6580. Nature Publishing Group
The P2X7 receptor plays a significant role in microglial activation, and as a potential drug target, the P2X7 receptor is also an interesting target in positron emission tomography. The current study aimed at the development and evaluation of a poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cc71df25ad681f797af725ffc97a78
https://doi.org/10.1038/s41598-018-24814-0
https://doi.org/10.1038/s41598-018-24814-0
Autor:
Bieneke, Janssen, Danielle J, Vugts, Shane M, Wilkinson, Dieter, Ory, Sylvie, Chalon, Jeroen J M, Hoozemans, Robert C, Schuit, Wissam, Beaino, Esther J M, Kooijman, Johan, van den Hoek, Mansoor, Chishty, Aurélie, Doméné, Anke, Van der Perren, Alessandro, Villa, Adriana, Maggi, Ger T, Molenaar, Uta, Funke, Rostislav V, Shevchenko, Veerle, Baekelandt, Guy, Bormans, Adriaan A, Lammertsma, Michael, Kassiou, Albert D, Windhorst
Publikováno v:
Scientific Reports
The P2X7 receptor plays a significant role in microglial activation, and as a potential drug target, the P2X7 receptor is also an interesting target in positron emission tomography. The current study aimed at the development and evaluation of a poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21b81817e8cfd68703e5cd406318447c
https://pubmed.ncbi.nlm.nih.gov/29700413
https://pubmed.ncbi.nlm.nih.gov/29700413
Autor:
Albert D. Windhorst, Uta Funke, Alex J. Poot, Aleksandra Pekošak, Ulrike Filp, Lonneke Rotteveel, Adriaan A. Lammertsma
Publikováno v:
Rotteveel, L, Poot, A J, Funke, U, Pekošak, A, Filp, U, Lammertsma, A A & Windhorst, A D 2017, ' Radiosynthesis of 1-iodo-2-[ 11 C]methylpropane and 2-methyl-1-[ 11 C]propanol and its application for alkylation reactions and C―C bond formation ', Journal of Labelled Compounds and Radiopharmaceuticals, vol. 60, no. 12, pp. 566-576 . https://doi.org/10.1002/jlcr.3536
Journal of Labelled Compounds and Radiopharmaceuticals, 60(12), 566-576. John Wiley and Sons Ltd
Journal of Labelled Compounds and Radiopharmaceuticals, 60(12), 566-576. John Wiley and Sons Ltd
The multitude of biologically active compounds requires the availability of a broad spectrum of radiolabeled synthons for the development of positron emission tomography (PET) tracers. The aim of this study was to synthesize 1-iodo-2-[11C]methylpropa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f54f37610dc09cbaedb9506ce32f93d
https://research.vumc.nl/en/publications/93800d09-bc91-46c9-9a09-e1978be8e18e
https://research.vumc.nl/en/publications/93800d09-bc91-46c9-9a09-e1978be8e18e
Autor:
Lonneke, Rotteveel, Alex J, Poot, Uta, Funke, Aleksandra, Pekošak, Ulrike, Filp, Adriaan A, Lammertsma, Albert D, Windhorst
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 60(12)
The multitude of biologically active compounds requires the availability of a broad spectrum of radiolabeled synthons for the development of positron emission tomography (PET) tracers. The aim of this study was to synthesize 1-iodo-2-[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e518fc3f8f243bd317cb7305bdc6f9f4
https://pubmed.ncbi.nlm.nih.gov/28755455
https://pubmed.ncbi.nlm.nih.gov/28755455