Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia

Autor: Dieter Kunz, Uta Eichmann, Richard Mahlberg, Sebastian Walther

Publikováno v: Walther, Sebastian; Mahlberg, Richard; Eichmann, Uta; Kunz, Dieter (2006). Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia. Psychopharmacology, 185(4), pp. 524-8. Berlin: Springer-Verlag 10.1007/s00213-006-0343-1

RATIONALE: Nighttime agitation occurs frequently in patients with dementia and represents the number one burden on caregivers today. Current treatment options are few and limited due to substantial side effects. OBJECTIVES: The aim of the study was t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7daa5d05bf0e78c68bd9506db87a95
http://doc.rero.ch/record/322101/files/213_2006_Article_343.pdf

Effects of rivastigmine on actigraphically monitored motor activity in severe agitation related to Alzheimer's disease: A placebo-controlled pilot study

Autor: Richard Mahlberg, Ferenc Tracik, Sebastian Walther, Dieter Kunz, Uta Eichmann

Publikováno v: Archives of Gerontology and Geriatrics. 45:19-26

Acetylcholinesterase inhibitors (AChEIs) are effective in the treatment of cognitive symptoms in Alzheimer's disease (AD). Because the behavioral and psychological symptoms of dementia (BPSD) have also been attributed to central cholinergic deficits,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b08b9878182641abb1740912df072ab
https://doi.org/10.1016/j.archger.2006.07.006

Lithium Augmentation Increases the ACTH and Cortisol Response in the Combined DEX/CRH Test in Unipolar Major Depression

Autor: Sieglinde Modell, Heike E. Künzel, Uta Eichmann, Bruno Müller-Oerlinghausen, Michael W. Bauer, Christopher Baethge, Tom Bschor, Mazda Adli, Marcus Ising, Manfred Uhr

Publikováno v: Neuropsychopharmacology. 27:470-478

Lithium augmentation is a well established strategy for treatment-resistant depression. The exact mode of its action is unknown, but an enhancement of serotonergic transmission is hypothesized. The authors investigated changes in the hypothalamic-pit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94741c8372ae6e3ad7a50e5936a09eae
https://doi.org/10.1016/s0893-133x(02)00323-8

Lithium augmentation increases post-dexamethasone cortisol in the dexamethasone suppression test in unipolar major depression

Autor: Tom, Bschor, Christopher, Baethge, Mazda, Adli, Uta, Eichmann, Marcus, Ising, Manfred, Uhr, Bruno, Müller-Oerlinghausen, Michael, Bauer

Publikováno v: Depression and anxiety. 17(1)

Although considerable evidence exists on the efficacy of lithium as an augmenting agent in refractory depression, the underlying neurobiology of this phenomenon is unknown. In patients with major depression, changes of the hypothalamic-pituitary-adre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ed9311ed59c300bfe89cf8e850f218b
https://pubmed.ncbi.nlm.nih.gov/12577277