Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Usha Nagavarapu"'
Autor:
Diana Lac, Maiko Hermsmeier, Xin Chen, Noymi Yam, Akira Yamamoto, Susan Huang, Tanvee Sawant, Kin F. Chan, Usha Nagavarapu
Publikováno v:
International Journal of Pharmaceutics: X, Vol 1, Iss , Pp - (2019)
Acne vulgaris is a clinically distinct skin condition with evidence suggesting that inflammation plays a critical role in the pathogenesis of this disorder. Treatment of severe inflammatory acne often involves the use of oral antibiotics, sometimes i
Externí odkaz:
https://doaj.org/article/2a172e8b72f14328b3a1304d994eb006
Publikováno v:
Lasers in Surgery and Medicine. 52:207-217
Background and objectives Successful outcomes of clinical studies for acne vulgaris depend greatly on achieving statistically significant reduction in acne lesion count and improvement in Investigator's Global Assessment score of the investigational
Autor:
Noymi Yam, Usha Nagavarapu, Tanvee Sawant, Kin F. Chan, Susan Huang, Xin Chen, Akira Yamamoto, Maiko Hermsmeier, Diana Lac
Publikováno v:
International Journal of Pharmaceutics: X
International Journal of Pharmaceutics: X, Vol 1, Iss, Pp-(2019)
International Journal of Pharmaceutics: X, Vol 1, Iss, Pp-(2019)
Graphical abstract
Acne vulgaris is a clinically distinct skin condition with evidence suggesting that inflammation plays a critical role in the pathogenesis of this disorder. Treatment of severe inflammatory acne often involves the use of oral
Acne vulgaris is a clinically distinct skin condition with evidence suggesting that inflammation plays a critical role in the pathogenesis of this disorder. Treatment of severe inflammatory acne often involves the use of oral
Autor:
Akira Yamamoto, Maiko Hermsmeier, Conor L. Evans, Kin F. Chan, Xin Chen, Sinyoung Jeong, Usha Nagavarapu
Publikováno v:
Biomedical optics express. 9(11)
In pharmacokinetic studies of topical drugs, fluorescence microscopy methods can enable the direct visualization and quantification of fluorescent drugs within the skin. One potential limitation of this approach, however, is the strong endogenous flu
Autor:
Xin Chen, Sinyoung Jeong, Akira Yamamoto, Maiko Hermsmeier, AnnaMarie Daniels, Sam Osseiran, Conor L. Evans, Kin F. Chan, Usha Nagavarapu
Publikováno v:
Photonics in Dermatology and Plastic Surgery 2018.
Oral minocycline has been the standard of care for the treatment of non-nodular moderate to severe inflammatory acne vulgaris due to its inhibitory effects on the acne-causing Propionibacterium acnes bacterium and its anti-inflammatory properties, De
Autor:
Akira Yamamoto, Maiko Hermsmeier, Usha Nagavarapu, Conor L. Evans, Sam Osseiran, Kin F. Chan, Sinyoung Jeong
Publikováno v:
Visualizing and Quantifying Drug Distribution in Tissue II.
Acne vulgaris is a common chronic skin disease in teenagers and young adults. Minocycline, an antibiotic, has thus far been widely utilized to treat acne, but only via oral administration. Recently, a topical minocycline gel (BPX-01) was developed to
Autor:
Usha Nagavarapu, Sinyoung Jeong, Xin Chen, Akira Yamamoto, Kin F. Chan, Conor L. Evans, Maiko Hermsmeier
Publikováno v:
Visualizing and Quantifying Drug Distribution in Tissue II.
The safety and efficacy of an investigational topical minocycline gel (BPX-01) has recently been studied in a Phase 2b trial for the treatment of acne vulgaris. As part of the drug development process, there was a need to determine if minocycline was
Autor:
Xin Chen, Akira Yamamoto, Conor L. Evans, Diana Lac, Kin F. Chan, Maiko Hermsmeier, Tanvee Sawant, Susan Y. Huang, Usha Nagavarapu, AnnaMarie Daniels
Publikováno v:
Photonics in Dermatology and Plastic Surgery.
Acne vulgaris is a chronic inflammatory skin condition commonly resulting in negative aesthetic and social impacts on those affected. Minocycline, currently available as an oral antibiotic for moderate to severe acne, has a known minimum inhibitory c
Autor:
Maiko Hermsmeier, Conor L. Evans, Diana Lac, Akira Yamamoto, Usha Nagavarapu, Tanvee Sawant, Kin F. Chan, Xin Chen
Publikováno v:
Visualizing and Quantifying Drug Distribution in Tissue.
Minocycline is an antibiotic regularly prescribed to treat acne vulgaris. The only commercially available minocycline comes in an oral dosage form, which often results in systemic adverse effects. A topical minocycline composition (BPX-01) was develo
Autor:
Akira Yamamoto, Conor L. Evans, Sam Osseiran, Maiko Hermsmeier, Sinyoung Jeong, Kin F. Chan, Usha Nagavarapu
Publikováno v:
Biomedical Optics Express. 9:3434
Acne vulgaris is a common chronic skin disease in young adults caused by infection of the pilosebaceous unit, resulting in pimples and possibly permanent scarring on the skin. Minocycline, a common antibiotic, has been widely utilized as a systemic a