Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Usha Kasid"'
Publikováno v:
Cancer Research. 77:P4-10
Breast cancer is the most common cancer diagnosed in women. Endoplasmic reticulum stress (EnR stress) and the related unfolded protein response (UPR) are activated in breast cancer cells and can promote cell survival and endocrine resistance. TMEM33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4899c9081d257348e8fd890669f535f8
https://doi.org/10.1158/1538-7445.sabcs16-p4-10-02
https://doi.org/10.1158/1538-7445.sabcs16-p4-10-02
Autor:
Bhaskar Kallakury, Christine E. Sheehan, Shantashri Vaidya, Usha Kasid, Jeffrey S. Ross, Timothy F. Day, Olga Voronel
Publikováno v:
Mol Cancer Res
Aberrant regulation of EGFR is common in non–small cell lung carcinomas (NSCLC), and tumor resistance to targeted therapies has been attributed to emergence of other co-occurring oncogenic events, parallel bypass receptor tyrosine kinase pathways i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aab3dc69eda37b58ad1ff3e38d9cca
https://europepmc.org/articles/PMC6497573/
https://europepmc.org/articles/PMC6497573/
Autor:
Usha Kasid, Robert Clarke
Publikováno v:
Methods in Molecular Biology ISBN: 9781493965373
Cancer Gene Networks
Cancer Gene Networks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::114e3914565af33fe333e01b84cb4422
https://doi.org/10.1007/978-1-4939-6539-7
https://doi.org/10.1007/978-1-4939-6539-7
Autor:
Xiaojun Zou, Rajshree R. Mewani, Timothy F. Day, Harvey B. Pollard, Meera Srivastava, Habtom W. Ressom, Ofer Eidelman, Joshua Starr, Debyani Chakravarty, Usha Kasid, Xin Li
Publikováno v:
Methods in Molecular Biology ISBN: 9781493965373
Tumor necrosis factor-α-inducible protein 8 (TNFAIP8) is the first discovered oncogenic and an anti-apoptotic member of a conserved TNFAIP8 or TIPE family of proteins. TNFAIP8 mRNA is induced by NF-kB, and overexpression of TNFAIP8 has been correlat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f07fd97e67c316ad376659b0103d4c8
https://doi.org/10.1007/978-1-4939-6539-7_7
https://doi.org/10.1007/978-1-4939-6539-7_7
Publikováno v:
Breast Cancer Research and Treatment
Endoplasmic reticulum (ER) stress leads to activation of the unfolded protein response (UPR) signaling cascade and induction of an apoptotic cell death, autophagy, oncogenesis, metastasis, and/or resistance to cancer therapies. Mechanisms underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e66fcb032753839aa05ace1d2fcf940
https://pubmed.ncbi.nlm.nih.gov/26268696
https://pubmed.ncbi.nlm.nih.gov/26268696
Autor:
Ayelet M. Samuni, Usha Kasid, Eric Y. Chuang, Simeng Suy, William DeGraff, Murali C. Krishna, Angelo Russo, James B. Mitchell
Publikováno v:
Cancer Research. 65:579-586
Despite significant evidence of a role of hypoxia in cellular resistance to ionizing radiation–induced toxicity, the underlying molecular mechanisms remain unclear. This study focused on the influence of hypoxia on radiation-induced signals in TK6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9af44ded615d554ab6ca88a487ffda
https://doi.org/10.1158/0008-5472.579.65.2
https://doi.org/10.1158/0008-5472.579.65.2
Publikováno v:
Cancer. 103:1302-1313
BACKGROUND In previous studies, nitroxide tempo (2, 2, 6, 6-tetramethyl-piperidine-1-oxyl), a small molecule, induced cell death in cancer cells. The current study examined the antineoplastic properties of tempo in the human hormone-dependent/hormone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5a06796fc47b74d7664067fee1565a
https://doi.org/10.1002/cncr.20898
https://doi.org/10.1002/cncr.20898
Autor:
Prafulla C. Gokhale, Deepak Kumar, John L. Marshall, Hedy L. Kindler, Mark J. Ratain, Chuanbo Zhang, Usha Kasid, Charles M. Rudin, Steve Wanaski, Chao Hui Huang, Joyce Steinberg
Publikováno v:
Clinical Cancer Research. 10:7244-7251
Purpose: Rapid cleavage in vivo and inefficient cellular uptake limit the clinical utility of antisense oligonucleotides (AON). Liposomal formulation may promote better intratumoral AON delivery and inhibit degradation in vivo. We conducted the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b1e42e621c9aeb192940b97c926c716
https://doi.org/10.1158/1078-0432.ccr-04-0642
https://doi.org/10.1158/1078-0432.ccr-04-0642
Autor:
Usha Kasid, Imran Ahmad, Anatoly Dritschilo, Prafulla C. Gokhale, Aquilur Rahman, Constantinos G. Broustas
Publikováno v:
Journal of Biological Chemistry. 279:26780-26788
We report here the structure-functional characterization of a novel intronless gene, BRCC2, located on human chromosome 11q24.1. BRCC2 open reading frame (327 bp) codes for an approximately 12-kDa protein (108 amino acids (aa)) localized predominantl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b4ecb0221d6cab1fcb11f7b4886422
https://doi.org/10.1074/jbc.m400159200
https://doi.org/10.1074/jbc.m400159200
Autor:
Anatoly Dritschilo, Prafulla C. Gokhale, Chuanbo Zhang, Imran Ahmad, Usha Kasid, Jin Pei, Aquilur Rahman
Publikováno v:
Anti-Cancer Drugs. 15:243-253
Raf-1 protein serine/threonine kinase plays an important role in cell proliferation and cell survival. We have previously described a novel cationic liposome-entrapped formulation of raf antisense oligodeoxyribonucleotide (LErafAON) and its use as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a4b2ca407f4b07bb2f692aab655814
https://doi.org/10.1097/00001813-200403000-00009
https://doi.org/10.1097/00001813-200403000-00009