Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Uryash, A."'
Autor:
Uryash, Arkady1 (AUTHOR) auryash@msmc.com, Mijares, Alfredo2 (AUTHOR) mijaresa@gmail.com, Lopez, Carlos E.3 (AUTHOR) carlos.lopez@deliverynetworkllc.com, Adams, Jose A.1 (AUTHOR) jose.adams@msmc.com, Allen, Paul D.4 (AUTHOR) paul_allen@hms.harvard.edu, Lopez, Jose R.5 (AUTHOR) lopezpadrino@icloud.com
Publikováno v:
Cells (2073-4409). Feb2024, Vol. 13 Issue 3, p264. 22p.
Publikováno v:
Cells, Vol 13, Iss 3, p 264 (2024)
Background: Postoperative cognitive dysfunction (POCD) is a common disorder after general anesthesia in elderly patients, the precise mechanisms of which remain unclear. Methods: We investigated the effect of isoflurane with or without dantrolene pre
Externí odkaz:
https://doaj.org/article/6e74645971b04eeba789094b61b10dd0
Autor:
Feng, Wei, Lopez, Jose R., Antrobus, Shane, Zheng, Jing, Uryash, Arkady, Dong, Yao, Beqollari, Donald, Bannister, Roger A., Hopkins, Philip M., Beam, Kurt G., Allen, Paul D., Pessah, Isaac.N.
Publikováno v:
In Journal of Biological Chemistry June 2023
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2596 (2023)
Type 2 diabetes mellitus (T2D) is a significant global public health problem that has seen a substantial increase in the number of affected individuals in recent decades. In a murine model of T2D (db/db), we found several abnormalities, including abe
Externí odkaz:
https://doaj.org/article/05820fb9b72f4444848afbd0e5e5b7c9
Akademický článek
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Autor:
Toshiko Yamazawa, Takuya Kobayashi, Nagomi Kurebayashi, Masato Konishi, Satoru Noguchi, Takayoshi Inoue, Yukiko U. Inoue, Ichizo Nishino, Shuichi Mori, Hiroto Iinuma, Noriaki Manaka, Hiroyuki Kagechika, Arkady Uryash, Jose Adams, Jose R. Lopez, Xiaochen Liu, Christine Diggle, Paul D. Allen, Sho Kakizawa, Keigo Ikeda, Bangzhong Lin, Yui Ikemi, Kazuto Nunomura, Shinsaku Nakagawa, Takashi Sakurai, Takashi Murayama
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Mutations in ryanodine receptor 1 (RyR1), a Ca2+ release channel in skeletal muscle, cause malignant hyperthermia (MH) and are involved in heat stroke. Here, the authors show that an oxolinic acid-derivative RyR1 inhibitor effectively prevents and tr
Externí odkaz:
https://doaj.org/article/afd2999f767e49b494c83b5f5e5c1a4b
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Skeletal muscle is the primary site of insulin-mediated glucose uptake through the body and, therefore, an essential contributor to glucose homeostasis maintenance. We have recently provided evidence that chronic elevated intracellular Ca2+ concentra
Externí odkaz:
https://doaj.org/article/659e616b58a94c6995a97511f1478f9a
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 623 (2023)
Duchenne muscular dystrophy (DMD) is an inherited muscular disorder caused by mutations in the dystrophin gene. DMD patients have hypoxemic events due to sleep-disordered breathing. We reported an anomalous regulation of resting intracellular Ca2+ ([
Externí odkaz:
https://doaj.org/article/350c03f1f788405c931ebef0fa19585a
Akademický článek
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