Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Urvashi V. Roongta"'
Autor:
Brent A. Rupnow, Tai W. Wong, R. Michael Lawrence, Malavi T. Madireddi, Jun Zhu, Wen-Pin Yang, Benjamin J. Henley, Joseph Fargnoli, Rolf-Peter Ryseck, Xinyu Wang, Jonathan G. Pabalan, Urvashi V. Roongta
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5f19996f7b7be9db5b7fb7f371b35a
https://doi.org/10.1158/1541-7786.22518582
https://doi.org/10.1158/1541-7786.22518582
Autor:
Brent A. Rupnow, Tai W. Wong, R. Michael Lawrence, Malavi T. Madireddi, Jun Zhu, Wen-Pin Yang, Benjamin J. Henley, Joseph Fargnoli, Rolf-Peter Ryseck, Xinyu Wang, Jonathan G. Pabalan, Urvashi V. Roongta
PDF file - 71K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26056af1bb8f6abaaf3538a0f9578a1c
https://doi.org/10.1158/1541-7786.22518573
https://doi.org/10.1158/1541-7786.22518573
Autor:
Brent A. Rupnow, Tai W. Wong, R. Michael Lawrence, Malavi T. Madireddi, Jun Zhu, Wen-Pin Yang, Benjamin J. Henley, Joseph Fargnoli, Rolf-Peter Ryseck, Xinyu Wang, Jonathan G. Pabalan, Urvashi V. Roongta
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec24b96c95c22de17c639d58869cf8e
https://doi.org/10.1158/1541-7786.22518576.v1
https://doi.org/10.1158/1541-7786.22518576.v1
Autor:
Brent A. Rupnow, Tai W. Wong, R. Michael Lawrence, Malavi T. Madireddi, Jun Zhu, Wen-Pin Yang, Benjamin J. Henley, Joseph Fargnoli, Rolf-Peter Ryseck, Xinyu Wang, Jonathan G. Pabalan, Urvashi V. Roongta
Emerging literature suggests that metabolic pathways play an important role in the maintenance and progression of human cancers. In particular, recent studies have implicated lipid biosynthesis and desaturation as a requirement for tumor cell surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1744961da814489eb070a9b55c9e7207
https://doi.org/10.1158/1541-7786.c.6542004
https://doi.org/10.1158/1541-7786.c.6542004
Autor:
Brent A. Rupnow, Tai W. Wong, R. Michael Lawrence, Malavi T. Madireddi, Jun Zhu, Wen-Pin Yang, Benjamin J. Henley, Joseph Fargnoli, Rolf-Peter Ryseck, Xinyu Wang, Jonathan G. Pabalan, Urvashi V. Roongta
PDF file - 39K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8112b61c9fece78abeaaa07d5a8f9ff9
https://doi.org/10.1158/1541-7786.22518579.v1
https://doi.org/10.1158/1541-7786.22518579.v1
Autor:
Saini Jasmine, Steven G. Nadler, Ashok Dongre, Aiqing He, Dmitry V. Ostanin, Clarence K. Zhang, Vishal Patel, Manling Ma-Edmonds, Jonathan G. Pabalan, Laurence Menard, Sherif Daouti, Sunil Kuppasani, Julie Carman, Li Fan, Omar Jabado, Matthew Loya, John R. Thompson, Ji Gao, Amy Truong, Urvashi V. Roongta
Publikováno v:
Gastroenterology. 156:S-873
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3113f105b9f462e7fa2b6bfd979be95f
https://doi.org/10.1016/s0016-5085(19)39148-6
https://doi.org/10.1016/s0016-5085(19)39148-6
Autor:
R. Michael Lawrence, Brent A. Rupnow, Malavi Madireddi, Xinyu Wang, Jonathan G. Pabalan, Tai W. Wong, Wen-Pin Yang, Benjamin J. Henley, Rolf-Peter Ryseck, Urvashi V. Roongta, Joseph Fargnoli, Jun Zhu
Publikováno v:
Molecular Cancer Research. 9:1551-1561
Emerging literature suggests that metabolic pathways play an important role in the maintenance and progression of human cancers. In particular, recent studies have implicated lipid biosynthesis and desaturation as a requirement for tumor cell surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c8e7f1c156e2966d8490facdb11d02
https://doi.org/10.1158/1541-7786.mcr-11-0126
https://doi.org/10.1158/1541-7786.mcr-11-0126
Autor:
Rawlins David B, Kevin R. Webster, Michael A. Poss, Chieh Ying Chang, Roberta Batorsky, Craig R. Fairchild, Toomas Mitt, Weifang Shan, Kristen A. Kellar, Hai Yun Xiao, John S. Tokarski, John T. Hunt, Francis Y. Lee, Janet G. Mulheron, Kyoung S. Kim, Nikola P. Pavletich, David Bol, Amrita Kamath, John S. Sack, Urvashi V. Roongta, Zhen Wei Cai, Isia Bursuker, Raj N. Misra, William G. Humphreys, Songfeng Lu, Wen Ching Han, Punit Marathe, S. David Kimball, Hong Zhu, Ligang Qian
Publikováno v:
Journal of Medicinal Chemistry. 45:3905-3927
High throughput screening identified 2-acetamido-thiazolylthio acetic ester 1 as an inhibitor of cyclin-dependent kinase 2 (CDK2). Because this compound is inactive in cells and unstable in plasma, we have stabilized it to metabolic hydrolysis by rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97262dbf4ae7cd3439043a8a4f6e0a73
https://doi.org/10.1021/jm0201520
https://doi.org/10.1021/jm0201520
Autor:
Hai Yun Xiao, Sunanda A. Ranadive, Kristen A. Kellar, Roberta Batorsky, Urvashi V. Roongta, John T. Hunt, Amrita Kamath, Rulin Zhao, Ligang Qian, Mark S. Bednarz, Kevin R. Webster, Francis Y.F. Lee, Syed Z. Ahmed, Weifang Shan, Nikola P. Pavletich, Kyoung Soo Kim, Stephanie Barbosa, Punit Marathe, John S. Sack, Raj N. Misra, Wen Ching Han, Janet G. Mulheron, S. David Kimball, Tokarski John S, Bang Chi Chen, David B. Rawlins, Songfeng Lu
Publikováno v:
Journal of Medicinal Chemistry. 58:7609-7609
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3380f506776520be66286064b833deb
https://doi.org/10.1021/acs.jmedchem.5b01294
https://doi.org/10.1021/acs.jmedchem.5b01294
Autor:
Joseph Fargnoli, Jonathan Lippy, Ashok V. Purandare, John T. Hunt, Libing Chen, Brian E. Fink, John S. Tokarski, Andrew Nation, Soong-Hoon Kim, Yufen Zhao, William R. Foster, Ashvinikumar V. Gavai, Tai W. Wong, Gregory D. Vite, Urvashi V. Roongta, Aberra Fura, Brent A. Rupnow, Jonathan G. Pabalan, Benjamin J. Henley, Christine M. Tarby, Mary T. Obermeier, Chiang Yu, Liqi He, Paul A. Elzinga
Publikováno v:
Cancer Research. 75:5417-5417
CK2 is a highly conserved, and constitutively active family of serine/threonine kinases abnormally elevated in a wide variety of cancers and linked to poor prognosis and disease progression. The enzymes form as hetero-tetrameric complexes comprised o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4be7e90e625f1f1f20fd7eb879bc6e
https://doi.org/10.1158/1538-7445.am2015-5417
https://doi.org/10.1158/1538-7445.am2015-5417