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of 4
pro vyhledávání: '"Urszula Wilczynska-Kalak"'
Autor:
Barbara Szymanska, Urszula Wilczynska-Kalak, Min H Kang, Natalia L M Liem, Hernan Carol, Ingrid Boehm, Daniel Groepper, C Patrick Reynolds, Clinton F Stewart, Richard B Lock
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33894 (2012)
Current regimens for induction therapy of pediatric acute lymphoblastic leukemia (ALL), or for re-induction post relapse, use a combination of vincristine (VCR), a glucocorticoid, and L-asparaginase (ASP) with or without an anthracycline. With cure r
Externí odkaz:
https://doaj.org/article/88670b55056c4fe1b0a9b4f77ad7b243
Autor:
Theresa M. Harned, Yun Hee Kang, Michael A. Sheard, Urszula Wilczynska-Kalak, Barbara Szymanska, Richard B. Lock, Min H. Kang, C. Patrick Reynolds
Publikováno v:
Blood. 110:2057-2066
Defects in apoptosis signaling contribute to poor outcome in pediatric acute lymphoblastic leukemia (ALL), and overexpression of antiapoptotic Bcl-2 (Bcl-2 and Bcl-XL) family proteins has been observed in ALL. ABT-737 is a small-molecule BH3-mimetic
Autor:
Min H. Kang, Barbara Szymanska, Natalia L. M. Liem, Hernan Carol, C. Patrick Reynolds, Ingrid Boehm, Daniel Groepper, Clinton F. Stewart, Urszula Wilczynska-Kalak, Richard B. Lock
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33894 (2012)
PLoS ONE
PLoS ONE
Current regimens for induction therapy of pediatric acute lymphoblastic leukemia (ALL), or for re-induction post relapse, use a combination of vincristine (VCR), a glucocorticoid, and l-asparaginase (ASP) with or without an anthracycline. With cure r
Autor:
Rosemary O'Brien, Richard B. Lock, Laura High, Urszula Wilczynska-Kalak, Andrew W. Roberts, Barbara Szymanska, Seong Lin Khaw, Nicole Barber, Ingela B. Vikstrom
Publikováno v:
Molecular pharmacology. 77(3)
Antiapoptotic Bcl-2 proteins are overexpressed in a number of cancers, including leukemias, and are frequently associated with resistance to conventional chemotherapeutic drugs. ABT-737, a Bcl-2 homology domain 3 mimetic (for structure, see Nature 43