Výsledky vyhledávání - "Urszula Uchiechowska"

Structure–Activity Studies on Splitomicin Derivatives as Sirtuin Inhibitors and Computational Prediction of Binding Mode

Autor: Henning Hruby, Robert C. Neugebauer, Manfred Jung, Urszula Uchiechowska, Wolfgang Sippl, Eric Verdin, Vassil Valkov, Rene Meier

Publikováno v: Journal of Medicinal Chemistry. 51:1203-1213

NAD (+)-dependent histone deacetylases (sirtuins) are enzymes that cleave acetyl groups from lysines in histones and other proteins. Potent selective sirtuin inhibitors are interesting tools for the investigation of the biological functions of those

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc516dfa1fe03b77690cffc62ba2872a
https://doi.org/10.1021/jm700972e

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Akademický článek

Structure–Activity Studies on Splitomicin Derivatives as Sirtuin Inhibitors and Computational Prediction of Binding Mode.

Autor: Robert C. Neugebauer, Urszula Uchiechowska, Rene Meier, Henning Hruby, Vassil Valkov, Eric Verdin, Wolfgang Sippl, Manfred Jung

Publikováno v: Journal of Medicinal Chemistry; Feb2008, Vol. 51 Issue 5, p1203-1213, 11p

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