Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Urszula Kulesza"'
Autor:
Maciej Rogacki, Stefan Chmielewski, Magdalena Zawadzka, Jolanta Mazurek, Katarzyna Wnuk-Lipińska, Kamil Kuś, Karolina Gluza, Katarzyna Wójcik-Jaszczyńska, Aleksandra Poczkaj, Lukasz Dudek, Wojciech Schonemann, Urszula Głowniak-Kwitek, Marcin Leś, Marek Wronowski, Tushar Mahajan, Urszula Kulesza, Magdalena Zastawna, David Synak, Karol Zuchowicz, Katarzyna Banaszak, Karolina Wiatrowska, Izabela Strojny, Mirosława Gładysz, Justyna Jabłońska, Ewelina Gabor-Worwa, Raghuram Tangirala, Luigi Stasi, Peter Littlewood, Krzysztof Brzózka, Monika Dobrzańska
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/58d89a86d62442c68347d687aa8c6180
Autor:
Urszula Wojcik-Trechcinska, Magdalena Masiejczyk, Agnieszka Dreas, Zuzanna Sandowska-Markiewicz, Michal Mikula, Jerzy Ostrowski, Katarzyna Kucwaj-Brysz, Karolina Pyziak, Ewelina Wincza, Mariusz Milik, Eliza Majewska, Tomasz Rzymski, Urszula Kulesza, Aniela Golas, Krzysztof Brzózka, Charles-Henry Fabritius, Kinga Michalik, Ewelina Gabor-Worwa, Kazimiera Pyśniak
The mitogen-activated protein kinase (MAPK)-interacting kinases 1 and 2 (MNKs 1/2) and their downstream target eIF4E, play a role in oncogenic transformation, progression and metastasis. These results provided rationale for development of first MNKs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257d9bec5056ffc8190e1768581a2973
https://ruj.uj.edu.pl/xmlui/handle/item/290102
https://ruj.uj.edu.pl/xmlui/handle/item/290102
Autor:
Magdalena Zastawna, Marcin Leś, Peter Littlewood, Karolina Wiatrowska, Izabela Strojny, Raghuram Tangirala, Katarzyna Wójcik-Jaszczyńska, Monika Dobrzańska, Tushar Mahajan, Stefan Chmielewski, Karolina Gluza, Kamil Kuś, Ewelina Gabor-Worwa, Urszula Głowniak-Kwitek, Magdalena Zawadzka, Justyna Jabłońska, Aleksandra Poczkaj, Maciej Rogacki, David Synak, Wojciech Schonemann, Jolanta Mazurek, Katarzyna Banaszak, Karol Zuchowicz, Krzysztof Brzózka, Katarzyna Wnuk-Lipinska, Mirosława Gładysz, Marek Wronowski, Urszula Kulesza, Luigi Stasi, Lukasz Piotr Dudek
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Stimulator of Interferon Genes (STING) is a major player in the activation of robust innate immune response leading to initiation and enhancement of tumor-specific adaptive immunity. Several clinical and pre-clinical programs have shown th
Autor:
Kinga Michalik, Karol Zuchowicz, Karolina Gluza, Anna Bartosik, Magdalena Zastawna, Wojciech Jasnosz, Nicolas Boutard, Andrzej Gondela, Eliza Zimoląg, Patryk Kret, Marta Bugaj, Aneta Bobowska, Sylwia Sudoł, Pawel Guzik, Maciej Kujawa, Peter Littlewood, Aleksandra Więckowska, Sujit Sasmal, David Synak, Katarzyna Banaszak, Przemysław Wyrębek, Joanna Szeremeta-Spisak, Wojciech Schonemann, Agnieszka Gibas, Mateusz Świrski, Marianna Girardi, Monika Dobrzańska, Michal Galezowski, Kostiantyn Krolenko, Marcin Nowogrodzki, Agata Dudek, Urszula Kulesza, Mateusz Ogórek, Krzysztof Brzózka, Katarzyna Wnuk-Lipinska, Oleksandr Leventes, Adrian Podkowa, Stefan Chmielewski
Publikováno v:
Cancer Research. 81:1281-1281
Background: Hematopoietic progenitor kinase 1 (HPK1, MAP4K1) is a member of the serine/threonine MAP4K family predominantly expressed in hematopoietic cell lineages which plays a pivotal role in the negative regulation of the signaling cascade trigge
Autor:
Mirosława Gładysz, Stefan Chmielewski, Karolina Gluza, Ewelina Gabor-Worwa, Monika Dobrzańska, Urszula Głowniak-Kwitek, Tushar Mahajan, Krzysztof Brzózka, David Synak, Aleksandra Poczkaj, Katarzyna Banaszak, Peter Littlewood, Karolina Wiatrowska, Katarzyna Wójcik-Jaszczyńska, Raghuram Tangirala, Karol Zuchowicz, Kamil Kuś, Marek Wronowski, Katarzyna Wnuk-Lipinska, Maciej Rogacki, Izabela Strojny, Wojciech Schonemann, Jolanta Mazurek, Magdalena Zastawna, Magdalena Zawadzka, Marcin Leś, Urszula Kulesza, Łukasz Dudek, Justyna Jabłońska
Publikováno v:
Cancer Research. 81:1280-1280
Background. Stimulator of interferon genes, known as STING, is an intracellular sensor of nucleic acids and one of key regulators in activating the innate immune response. Employing synthetic STING agonists has been shown to promote immune-mediated a
Publikováno v:
Tree Genetics & Genomes. 15
Many plant species can reproduce by both sexual and vegetative means. Clonal diversity and degree of intermingling of clones in the vegetative reproductive mode can influence the mating and fertility of individuals. The aim of the study was to assess
Autor:
Jose Alvarez, Agnieszka Dreas, Kamila Kozłowska, Kinga Michalik, Magdalena Zastawna, Anna Wrobel, Karol Zuchowicz, Andrzej Mazan, Peter Littlewood, Justyna Martyka, Magdalena Łośko, Tomasz Rzymski, Agnieszka Sroka-Porada, Paulina Niedziejko, Urszula Kulesza, Luigi Stasi, Joanna Szczęśniak, Krzysztof Brzózka, Adam Radzimierski, Katarzyna Wnuk-Lipinska, Katarzyna Wiklik, Anna Kowal
Publikováno v:
Cancer Research. 80:3656-3656
Background: Synthetic lethality is one of the most innovative approaches for selective targeting of cancer cells with defined genetic background. SMARCA2 and SMARCA4 are two mutually exclusive helicase/ATPase catalytic subunits belonging to SWI/SNF c
Publikováno v:
Journal of Medicinal Chemistry. 58:6237-6247
Continuing the structure-activity relationship studies in the vitamin D area, we designed and synthesized novel C-9 substituted calcitriol analogues, possessing different nonpolar groups at this position. 9α-Methyl-1α,25-(OH)2D3, both epimers of 9-
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 136:23-26
9-Alkylidene analogs of 19-nor-1α,25-(OH) 2 D 3 were synthesized, possessing a ‘reversed’ triene system compared to the natural hormone. The conjugated triene moiety of the novel analogs was constructed by coupling an enyne anion, representing a
Publikováno v:
Organicbiomolecular chemistry. 14(5)
The UV-induced photochemical reaction of 1α,25-dihydroxy-9-methylene-19-norvitamin D3 has been investigated. The pentacyclic structure of the isolated product has been unequivocally established by X-ray crystallographic analysis. The possible reacti