Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Urszula Krzemien"'
Autor:
Adriana Aguilar-Mahecha, Sarah Joseph, Luca Cavallone, Marguerite Buchanan, Urszula Krzemien, Gerald Batist, Mark Basik
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Trastuzumab, has played a major role in improving treatment outcomes in HER-2 positive gastric cancer. However, once there is disease progression there is a paucity of evidence for second line therapy. Patient-derived xenografts (PDXs) in combination
Externí odkaz:
https://doaj.org/article/e2b407473553426cab80825eaabdd441
Autor:
Mark Basik, Jacek Majewski, Catalin Mihalcioiu, Elizabeth A. Marcus, André Robidoux, Josée-Anne Roy, Peter Tonellato, Sheida Nabavi, Eric Bareke, Christoph H. Borchers, René P. Zahedi, Vincent R. Richard, Stephen D. Hursting, Ciara O'Flanagan, Sylvia Josephy, Horace Uri Saragovi, Moulay Alaoui-Jamali, Amine Saad, Naciba Benlimame, Marie-Christine Guilbert, Cristiano Ferrario, Olga Aleynikova, Luca Cavallone, Urszula Krzemien, Cathy Lan, Ewa Przybytkowski, Stéphanie Légaré, Banujan Balachandran, Aparna Ramanathan, Catherine Chabot, Marguerite Buchanan, Michelle Scriver, Viet Vu, Emma Fowler, Josiane Lafleur, Adriana Aguilar-Mahecha, Isabelle Sirois
Supplementary Figure 1 a. Doxorubicin resistance of DOXO-R C8 cells was further validated using the cell viability assay (SRB) following 48 hrs treatment with DOXO, n=4 independent experiment, 3 replicates/experiment. **p0.6 and pval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5951da76f101d8988229319ab24ea931
https://doi.org/10.1158/1541-7786.22515963
https://doi.org/10.1158/1541-7786.22515963
Autor:
Mark Basik, Jacek Majewski, Catalin Mihalcioiu, Elizabeth A. Marcus, André Robidoux, Josée-Anne Roy, Peter Tonellato, Sheida Nabavi, Eric Bareke, Christoph H. Borchers, René P. Zahedi, Vincent R. Richard, Stephen D. Hursting, Ciara O'Flanagan, Sylvia Josephy, Horace Uri Saragovi, Moulay Alaoui-Jamali, Amine Saad, Naciba Benlimame, Marie-Christine Guilbert, Cristiano Ferrario, Olga Aleynikova, Luca Cavallone, Urszula Krzemien, Cathy Lan, Ewa Przybytkowski, Stéphanie Légaré, Banujan Balachandran, Aparna Ramanathan, Catherine Chabot, Marguerite Buchanan, Michelle Scriver, Viet Vu, Emma Fowler, Josiane Lafleur, Adriana Aguilar-Mahecha, Isabelle Sirois
Table S18: Two-way ANOVA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee4709fac1d7833473c13afa1ca590d
https://doi.org/10.1158/1541-7786.22515954.v1
https://doi.org/10.1158/1541-7786.22515954.v1
Autor:
Mark Basik, Jacek Majewski, Catalin Mihalcioiu, Elizabeth A. Marcus, André Robidoux, Josée-Anne Roy, Peter Tonellato, Sheida Nabavi, Eric Bareke, Christoph H. Borchers, René P. Zahedi, Vincent R. Richard, Stephen D. Hursting, Ciara O'Flanagan, Sylvia Josephy, Horace Uri Saragovi, Moulay Alaoui-Jamali, Amine Saad, Naciba Benlimame, Marie-Christine Guilbert, Cristiano Ferrario, Olga Aleynikova, Luca Cavallone, Urszula Krzemien, Cathy Lan, Ewa Przybytkowski, Stéphanie Légaré, Banujan Balachandran, Aparna Ramanathan, Catherine Chabot, Marguerite Buchanan, Michelle Scriver, Viet Vu, Emma Fowler, Josiane Lafleur, Adriana Aguilar-Mahecha, Isabelle Sirois
Table S1: List of regions of genes with increased CNV (>= 0.5) and gene expression (>= 0.5) in DOXO-R cells compared to parental cells Table S2: List of all fold change and pvalue of DOXO-R C1 and C8 (vs parental cells) from gene expression analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14ecb9da2642b74d4a5b22b716b9132
https://doi.org/10.1158/1541-7786.22515957.v1
https://doi.org/10.1158/1541-7786.22515957.v1
Autor:
Mark Basik, Jacek Majewski, Catalin Mihalcioiu, Elizabeth A. Marcus, André Robidoux, Josée-Anne Roy, Peter Tonellato, Sheida Nabavi, Eric Bareke, Christoph H. Borchers, René P. Zahedi, Vincent R. Richard, Stephen D. Hursting, Ciara O'Flanagan, Sylvia Josephy, Horace Uri Saragovi, Moulay Alaoui-Jamali, Amine Saad, Naciba Benlimame, Marie-Christine Guilbert, Cristiano Ferrario, Olga Aleynikova, Luca Cavallone, Urszula Krzemien, Cathy Lan, Ewa Przybytkowski, Stéphanie Légaré, Banujan Balachandran, Aparna Ramanathan, Catherine Chabot, Marguerite Buchanan, Michelle Scriver, Viet Vu, Emma Fowler, Josiane Lafleur, Adriana Aguilar-Mahecha, Isabelle Sirois
The major obstacle in successfully treating triple-negative breast cancer (TNBC) is resistance to cytotoxic chemotherapy, the mainstay of treatment in this disease. Previous preclinical models of chemoresistance in TNBC have suffered from a lack of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8977b5f5ea9cc4145130c77246c005e6
https://doi.org/10.1158/1541-7786.c.6541230
https://doi.org/10.1158/1541-7786.c.6541230
Autor:
Mark Basik, Cristiano Ferrario, Michael Pollak, Josiane Lafleur, Marguerite Buchanan, Abdel Hosein, Urszula Krzemien, Adriana Aguilar-Mahecha, Yirui Gui
Figure S4 shows the top differentially regulated genes between mCAFs vs pCAFs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5101cfd098a852727e5d5b02d1d655
https://doi.org/10.1158/1078-0432.22471641.v1
https://doi.org/10.1158/1078-0432.22471641.v1
Autor:
Mark Basik, Cristiano Ferrario, Michael Pollak, Josiane Lafleur, Marguerite Buchanan, Abdel Hosein, Urszula Krzemien, Adriana Aguilar-Mahecha, Yirui Gui
Supplementary Table1 Clinical information of tumors from which used CAFs isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44761c53a225d6b7ad30537bde1036dd
https://doi.org/10.1158/1078-0432.22471623
https://doi.org/10.1158/1078-0432.22471623
Autor:
Mark Basik, Cristiano Ferrario, Michael Pollak, Josiane Lafleur, Marguerite Buchanan, Abdel Hosein, Urszula Krzemien, Adriana Aguilar-Mahecha, Yirui Gui
Figure S1-S8 legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5869cc16f9d9b52b61965d8e57387013
https://doi.org/10.1158/1078-0432.22471626
https://doi.org/10.1158/1078-0432.22471626
Autor:
Kathryn Bozek, Marguerite Buchanan, Cathy Lan, Josiane Lafleur, Cedric Darini, Urszula Krzemien, Adriana Aguilar-Mahecha, Mark Basik
Publikováno v:
Cancer Research. 82:1794-1794
Background: Her2+ breast cancer accounts for 15% of breast cancer cases and is primarily treated with a combination of Her2-targeted agents and chemotherapy. While use of targeted agents has substantially improved survival of these patients, clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a476f1cc8d543827b88f0374b5240c3c
https://doi.org/10.1158/1538-7445.am2022-1794
https://doi.org/10.1158/1538-7445.am2022-1794
Autor:
Adriana Aguilar-Mahecha, Yirui Gui, Urszula Krzemien, Josiane P. Lafleur, Abdel Hosein, Marguerite Buchanan, Michael Pollak, Cristiano Ferrario, Mark Basik
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(23)
Purpose: The microenvironment of metastatic breast cancer is incompletely characterized, despite prior evidence that it plays a key role in the biology of metastasis. A major component of the tumor stroma is the carcinoma-associated fibroblast (CAF),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a69034ace2b43e13b986c037732ec33
https://pubmed.ncbi.nlm.nih.gov/31515454
https://pubmed.ncbi.nlm.nih.gov/31515454