Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Urszula Grabowska"'
Clinical usefulness of pentraxin 3 (PTX3) as a biomarker of acute pancreatitis and pancreatic cancer
Autor:
Stanislaw Gluszek, Jarosław Matykiewicz, Urszula Grabowska, Magdalena Chrapek, Lukasz Nawacki, Iwona Wawrzycka, Martyna Gluszek-Osuch, Dorota Kozieł
Publikováno v:
Studia Medyczne, Vol 36, Iss 1, Pp 6-13 (2020)
Externí odkaz:
https://doaj.org/article/92d05c3d9a374d4298d3435d1615b202
Autor:
Philip A. P. Reeve, Urszula Grabowska, Lourdes Salvador Oden, Daniel Wiktelius, Fredrik Wångsell, Richard F. W. Jackson
Publikováno v:
ACS Omega, Vol 4, Iss 6, Pp 10854-10865 (2019)
Externí odkaz:
https://doaj.org/article/aba17e3c7c414378b660bf2669f91fc2
Publikováno v:
International Journal of Occupational Medicine and Environmental Health, Vol 31, Iss 6, Pp 741-751 (2018)
Objectives The term metabolic syndrome (MetS) refers to the coexistence of interlinked risk factors of metabolic origin, contributing to the development of arteriosclerotic cardiovascular diseases as well as type 2 diabetes and their cardiovascular c
Externí odkaz:
https://doaj.org/article/44e9e3a9f3f445e79810fc49c041e4ef
Autor:
Erik Lindström, Biljana Rizoska, Ian Henderson, Ylva Terelius, Markus Jerling, Charlotte Edenius, Urszula Grabowska
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract Background Cathepsin K is an attractive therapeutic target for diseases in which bone resorption is excessive such as osteoporosis and osteoarthritis (OA). The current paper characterized the pharmacological profile of the potent and selecti
Externí odkaz:
https://doaj.org/article/382cff9db65d44afb7a828169477e087
Autor:
Erik Lindström, Biljana Rizoska, Karin Tunblad, Charlotte Edenius, Alison M. Bendele, Don Maul, Michael Larson, Neha Shah, Valerie Yoder Otto, Chris Jerome, Urszula Grabowska
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background MIV-711 is a highly potent and selective cathepsin K inhibitor. The current article summarizes the therapeutic effects of MIV-711 on joint pathology in rabbits subjected to anterior cruciate ligament transection (ACLT), and the pr
Externí odkaz:
https://doaj.org/article/091b4e96d00f43a7a8556bd402944cd7
Publikováno v:
Studia Medyczne, Vol 33, Iss 4, Pp 262-269 (2017)
Introduction : Determination of predictors of survival and hospitalization can optimise a medical care of patient with permanent pacemaker. Aim of the research : Use of the B-type natriuretic peptide (BNP), high-sensitivity troponin T (TnT hs), and l
Externí odkaz:
https://doaj.org/article/9eb633670b754146b978738c33f28b06
Autor:
Paweł Wałek, Urszula Grabowska, Elżbieta Cieśla, Janusz Sielski, Joanna Roskal-Wałek, Beata Wożakowska-Kapłon
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1108 (2021)
Galectin-3 (gal-3) is a fibrosis marker and may play a role in fibrosis of the left atrium (LA). Left atrial wall fibrosis may influence the transition from paroxysmal to non-paroxysmal atrial fibrillation (AF). In this study, we assessed the correla
Externí odkaz:
https://doaj.org/article/acaa442978624ed8b813164706042296
Autor:
Lilian N. Nwosu, Peter R.W. Gowler, James J. Burston, Biljana Rizoska, Karin Tunblad, Erik Lindström, Urszula Grabowska, Li Li, Dan F. McWilliams, David A. Walsh, Victoria Chapman
Publikováno v:
PAIN Reports, Vol 3, Iss 6, p e685 (2018)
Abstract. Introduction:. The mounting evidence that osteoclasts play an important role in osteoarthritis (OA) pain lead us to investigate the effects of L-006235, a potent and selective inhibitor of cathepsin K, on pain behaviour and joint pathology
Externí odkaz:
https://doaj.org/article/4771b6815baa4660a719f82d83a56971
Publikováno v:
Studia Medyczne, Vol 31, Iss 4, Pp 241-248 (2016)
Introduction: The present study was undertaken to evaluate the practical value of BNP measurements and echocardiographic left ventricular volume index in patients with permanent pacemakers because there are no such reports in the literature. Aim of t
Externí odkaz:
https://doaj.org/article/0a670460f7ef45e1a47b1318468c9cfa
Autor:
Timothy A. Yap, Patricia M. LoRusso, Deborah J. Wong, Siwen Hu-Lieskovan, Kyriakos P. Papadopoulos, Josefin-Beate Holz, Urszula Grabowska, Cristian Gradinaru, Kin-Mei Leung, Sylwia Marshall, Claire S. Reader, Roslin Russell, Richard C.A. Sainson, Claire J. Seal, Christopher J. Shepherd, Fiona Germaschewski, Daniel Gliddon, Omer Stern, Lesley Young, Neil Brewis, Louis Kayitalire, Michelle Morrow
Publikováno v:
Clinical Cancer Research. 29:888-898
Purpose:This phase 1 study (NCT03440437) evaluated the safety, tolerability, pharmacokinetics (PK), and activity of FS118, a bispecific antibody–targeting LAG-3 and PD-L1, in patients with advanced cancer resistant to anti–PD-(L)1 therapy.Patient