Histone H3 clipping is a novel signature of human neutrophil extracellular traps

Autor: Dorothea Ogmore Tilley, Ulrike Abuabed, Ursula Zimny Arndt, Monika Schmid, Stefan Florian, Peter R Jungblut, Volker Brinkmann, Alf Herzig, Arturo Zychlinsky

Publikováno v: eLife, Vol 11 (2022)

Neutrophils are critical to host defence, executing diverse strategies to perform their antimicrobial and regulatory functions. One tactic is the production of neutrophil extracellular traps (NETs). In response to certain stimuli, neutrophils deconde

Externí odkaz: https://doaj.org/article/d8e432b742664c989e77339c1d4ebdff

Quantitative phosphoproteomics reveals link between Helicobacter pylori infection and RNA splicing modulation in host cells

Autor: Carsten Holland, Thomas F. Meyer, John Rohloff, Ursula Zimny-Arndt, Robert Stein, Monika Schmid, Peter R. Jungblut

Publikováno v: PROTEOMICS. 11:2798-2811

The Gram-negative, spiral-shaped bacterium Helicobacter pylori is a common human pathogen that causes chronic inflammation of the human gastric mucosa, leading to peptic ulceration and/or gastric cancer. Here, we analyzed changes in the phosphoproteo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfa54a61bf3fdc1bc19b9326605889b
https://doi.org/10.1002/pmic.201000793

Gene expression and protein profiling of AGS gastric epithelial cells upon infection withHelicobacter pylori

Autor: Wolfgang König, Peter R. Jungblut, Helga Gressmann, Ursula Zimny-Arndt, Terry Kwok, Steffen Backert, Thomas F. Meyer

Publikováno v: PROTEOMICS. 5:3902-3918

Helicobacter pylori, one of the most common bacterial pathogens, colonizes the human stomach and causes a variety of gastric diseases. This pathogen elicits a range of phenotypic responses in infected cultured AGS gastric epithelial cells, including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b18644e393eaef614a5af9e15c9574
https://doi.org/10.1002/pmic.200401240

Proteomic Identification of M.tuberculosis Protein Kinase Substrates: PknB Recruits GarA, a FHA Domain-containing Protein, Through Activation Loop-mediated Interactions

Autor: Pedro M. Alzari, Priscille Brodin, Carlos Cerveñansky, Patrick England, Ursula Zimny-Arndt, Peter R. Jungblut, Pablo Fernandez, Annemarie Wehenkel, Andrea Villarino, Stewart T. Cole, Rosario Durán

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2005, 350 (5), pp.953-963. ⟨10.1016/j.jmb.2005.05.049⟩
Journal of Molecular Biology, 2005, 350 (5), pp.953-963. ⟨10.1016/j.jmb.2005.05.049⟩

International audience; Genes for functional Ser/Thr protein kinases (STPKs) are ubiquitous in prokaryotic genomes, but little is known about their physiological substrates and their actual involvement in bacterial signal transduction pathways. We re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a485bb7db03d00fa551b2b2bcba935
https://doi.org/10.1016/j.jmb.2005.05.049

Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial pathogens

Autor: Hans-Joachim Mollenkopf, Ulrich E. Schaible, Stefan H. E. Kaufmann, Bärbel Raupach, Ursula Zimny-Arndt, Stephanie Lamer, Peter R. Jungblut, Jens Mattow, Petr Halada, Kristine Hagens

Publikováno v: Molecular Microbiology. 33:1103-1117

In 1993, the WHO declared tuberculosis a global emergency on the basis that there are 8 million new cases per year. The complete genome of the strain H37Rv of the causative microorganism, Mycobacterium tuberculosis, comprising 3924 genes has been seq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d1acfae5209f927e3cb28f530268473
https://doi.org/10.1046/j.1365-2958.1999.01549.x