Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ursula Waack"'
Autor:
Tracy L. Nicholson, Ursula Waack, Damarius S. Fleming, Qing Chen, Laura C. Miller, Tod J. Merkel, Scott Stibitz
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Bordetella bronchiseptica is a highly contagious respiratory bacterial veterinary pathogen. In this study the contribution of the transcriptional regulators BvgR, RisA, RisS, and the phosphorylation of RisA to global gene regulation, intracellular cy
Externí odkaz:
https://doaj.org/article/5edfd29f8a474e468f0b0e409d86ca01
Autor:
Tracy L. Nicholson, Ursula Waack, Tavis K. Anderson, Darrell O. Bayles, Sam R. Zaia, Isaiah Goertz, Mark Eppinger, Samantha J. Hau, Susan L. Brockmeier, Sarah M. Shore
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Streptococcus suis is a zoonotic bacterial swine pathogen causing substantial economic and health burdens to the pork industry. Mechanisms used by S. suis to colonize and cause disease remain unknown and vaccines and/or intervention strategies curren
Externí odkaz:
https://doaj.org/article/b33d2385519146deabcc4704f1ef243e
Autor:
Ursula Waack, Mark Warnock, Andrew Yee, Zachary Huttinger, Sara Smith, Ayush Kumar, Alban Deroux, David Ginsburg, Harry L. T. Mobley, Daniel A. Lawrence, Maria Sandkvist
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Antibiotic-resistant Acinetobacter baumannii is increasingly recognized as a cause of difficult-to-treat nosocomial infections, including pneumonia, wound infections, and bacteremia. Previous studies have demonstrated that the metalloproteas
Externí odkaz:
https://doaj.org/article/d973548e5bd446dbbe654031c2645100
Autor:
Ursula Waack, Tracy L. Nicholson
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Streptococcus suis is a bacterial swine pathogen with a significant economic burden. It typically colonizes the tonsil and nasal cavity of swine causing a variety of symptoms ranging from asymptomatic carriage to lethal systemic disease. A key barrie
Externí odkaz:
https://doaj.org/article/b632e09db4394a488d194b1da25f04a3
Autor:
Ursula Waack, Tanya L. Johnson, Khalil Chedid, Chuanwu Xi, Lyle A. Simmons, Harry L. T. Mobley, Maria Sandkvist
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Nosocomial pathogens that develop multidrug resistance present an increasing problem for healthcare facilities. Due to its rapid rise in antibiotic resistance, Acinetobacter baumannii is one of the most concerning gram-negative species. A. baumannii
Externí odkaz:
https://doaj.org/article/e4389c96c3a845228c95e59ee2ef22bf
Autor:
Tori Kinamon, Ramya Gopinath, Ursula Waack, Mark Needles, Daniel Rubin, Deborah Collyar, Sarah B Doernberg, Scott Evans, Toshimitsu Hamasaki, Thomas L Holland, Jessica Howard-Anderson, Henry Chambers, Vance G Fowler, Sumati Nambiar, Peter Kim, Helen W Boucher
Publikováno v:
Clinical Infectious Diseases.
Background Desirability of outcome ranking (DOOR) is a novel approach to clinical trial design that incorporates safety and efficacy assessments into an ordinal ranking system to evaluate overall outcomes of clinical trial participants. Here, we deri
Autor:
Yuliya Yasinskaya, Shukal Bala, Ursula Waack, Cheryl Dixon, Karen Higgins, Jason N Moore, Caroline J Jjingo, Elizabeth O'Shaughnessy, Philip Colangelo, Radu Botgros, Sumathi Nambiar, David Angulo, Aaron Dane, Tom Chiller, Michael R Hodges, Taylor Sandison, William Hope, Thomas J Walsh, Peter Pappas, Aspasia Katragkou, Laura Kovanda, John H Rex, Kieren A Marr, Luis Ostrosky-Zeichner, Shohko Sekine, Monika Deshpande, Sunita J Shukla, John Farley
Publikováno v:
Clinical Infectious Diseases.
Pressing challenges in the treatment of invasive fungal infections (IFIs) include emerging and rare pathogens, resistant/refractory infections, and antifungal armamentarium limited by toxicity, drug-drug interactions, and lack of oral formulations. D
Autor:
Tori Kinamon, Ramya Gopinath, Ursula Waack, Mark Needles, Daniel Rubin, Deborah Collyar, Sarah B Doernberg, Scott R Evans, Toshimitsu Hamasaki, Thomas L Holland, Jessica Howard-Anderson, Henry Chambers, Vance G Fowler, Sumathi Nambiar, Peter Kim, Helen W Boucher
Publikováno v:
Open Forum Infectious Diseases. 9
Background Desirability of outcome ranking (DOOR) uses an ordinal ranking system to evaluate global outcomes in clinical trial participants by incorporating safety and efficacy assessments into a single endpoint. In this study, we developed and appli
Publikováno v:
Journal of Antimicrobial Chemotherapy. 76:2884-2889
Background An antibacterial drug’s susceptibility test interpretive criteria (STIC) are determined by integrating clinical, microbiological and pharmacokinetic-pharmacodynamic (PK-PD) data. PTA analysis plays a pivotal or supportive role in STIC de
Autor:
Abhay Joshi, Jürgen B. Bulitta, Binh An Diep, John Farley, Alexander J. Lepak, Ursula Waack, James M Byrne, Thomas J. Walsh, Edward A. Weinstein, Andrew J Phipps, Lynn Miesel, Dmitri Iarikov, Matthew B. Lawrenz, Simone M Shurland, Brian Luna, William W. Hope, Tina Guina, Thushi Amini, William J. Weiss
Publikováno v:
Antimicrob Agents Chemother
The U.S. Food and Drug Administration (FDA) hosted a public workshop entitled “Advancing Animal Models for Antibacterial Drug Development” on 5 March 2020. The workshop mainly focused on models of pneumonia caused by Pseudomonas aeruginosa and Ac