Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ursula Mocek"'
Autor:
Heinz G. Floss, Ursula Mocek
Publikováno v:
TAXOL® ISBN: 9780138737368
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::180c4eb454cc6856bf11a02f6a4fd65c
https://doi.org/10.1201/9780138737361-10
https://doi.org/10.1201/9780138737361-10
Autor:
Ursula Mocek, Ted L. Underiner, Sheldon E. Broedel, Gail E. McElhaney-Feser, Robert E. Raulli, Jodi A. Laakso, Paul Actor, Brian J. Hotovec, Ronald L. Cihlar
Publikováno v:
Journal of Natural Products. 66:1041-1046
A systematic screen for new natural products that displayed antifungal activity by inhibition of fungal fatty acid synthase (FAS) led to the discovery of two new fungal metabolites, designated CT2108A (1) and CT2108B (2). The metabolites were produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed488c143650a930af65d96c4a156141
https://doi.org/10.1021/np030046g
https://doi.org/10.1021/np030046g
Autor:
Thomas Frenzel, Ursula Mocek, Meinhart H. Zenk, John M. Beale, Motomasa Kobayashi, Heinz G. Floss, Jeffrey A. Bjorklund, Martina Rueffer, Christina Fox, Stefan Groeger
Publikováno v:
Journal of the American Chemical Society. 117:1533-1545
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a97f58227c8260c690ebddff5609f31f
https://doi.org/10.1021/ja00110a009
https://doi.org/10.1021/ja00110a009
Autor:
Juergen Rohr, Heike Bockholt, John M. Beale, Gyoergyi Udvarnoki, Ursula Mocek, Heinz G. Floss
Publikováno v:
The Journal of Organic Chemistry. 59:2064-2069
Feeding experiments with 13 C and 18 O-labeled precursors revealed that the polycyclic xanthone antibiotics, the lysolipins X (1) and I (2), is derived from the polyketide pathway (12 malonate units), the C 1 pool (methionine), molecular oxygen, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc8ab3c683e9a0d6b27dbad9c8b5c4a0
https://doi.org/10.1021/jo00087a021
https://doi.org/10.1021/jo00087a021
Autor:
Paul E. Fleming, Kevin Walker, Andrew R. Knaggs, M. Haertel, Heinz G. Floss, Ursula Mocek, A. Lansing
Publikováno v:
Pure and Applied Chemistry. 66:2045-2048
The biosynthesis of the plant antitumor agent, taxol, was studied by feeding radioactive or stable isotope-labeled precursors to cut stems or to inner bark tissue of Taxus brevifolia. The labeled taxol was purified to radiochemical purity and subject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc4e5c7a27231d27b8d8fbb73f06613b
https://doi.org/10.1351/pac199466102045
https://doi.org/10.1351/pac199466102045
Autor:
Ursula Mocek, Kyung Hwan Han, Heinz G. Floss, Kevin Walker, W. Scott Chilton, Milton P. Gordon, Matthew Loper, Paul E. Fleming
Publikováno v:
Plant Science. 95:187-196
This report demonstrates genetic transformation of two Taxus species. Taxus brevifolia and Taxus baccata, and expression of bacterial genes transferred into the plant genome by Agrobacterium tumefaciens. We used two strains of Agrobacterium tumefacie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::254f2145f6abf1e6a044dacdcebd62e9
https://doi.org/10.1016/0168-9452(94)90092-2
https://doi.org/10.1016/0168-9452(94)90092-2
Autor:
Joshua Rhea, Tim Morley, Zhicai Yang, Michael Guaciaro, Ursula Mocek, Ricardo Reategui, Bruce F Molino, Xiaomin Jin
Publikováno v:
Organic letters. 13(20)
A total synthesis of both diastereomers of the originally proposed structure for streptophenazine A (1) has been achieved. However, both synthetic compounds are different from the natural product. Re-examination of NMR data reported for streptophenaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8687c7eb60b8198988914f15d0dcf7a4
https://pubmed.ncbi.nlm.nih.gov/21958197
https://pubmed.ncbi.nlm.nih.gov/21958197
Autor:
Ursula Mocek, Cynthia Graff, Satoshi Omura, Hyeongjin Cho, John M. Beale, Heinz G. Floss, Akira Nakagawa
Publikováno v:
Journal of the American Chemical Society. 115:12296-12304
The biosynthesis of the antibiotic reductiomycin (I) in Streptomyces xanthochromogenus was investigated by feeding experiments with radioactive and stable isotope-labeled precursors. NMR and mass spectroscopic analyses of the labeled I samples reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40287ac6077b7724c468fa9506e1d95
https://doi.org/10.1021/ja00079a009
https://doi.org/10.1021/ja00079a009
Publikováno v:
The Journal of Organic Chemistry. 58:6576-6582
The biosynthesis of the phenazine antibiotics, the esmeraldins and the related saphenamycins, was studied by feeding radioactive and stable isotope-labeled precursors to Streptomyces antibioticus, strain Tu 2706. After purification, the labeled antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d694f5995bbd942724a5d5f03b7b881c
https://doi.org/10.1021/jo00076a014
https://doi.org/10.1021/jo00076a014
Autor:
John M. Beale, Zhaopie Zeng, Pei Zhou, David O'Hagan, Lai Duen G. Fan, Ursula Mocek, Heinz G. Floss
Publikováno v:
Journal of the American Chemical Society. 115:7992-8001
The biosynthesis of the thiopeptide antibiotic thiostrepton (1) has been investigated by administration of isotopically labeled precursors to cultures of Streptomyces azureus and Streptomyces laurentii. The amino acid origin of all the components of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54252fdbf05fd4bba6739252a4a2f3af
https://doi.org/10.1021/ja00071a009
https://doi.org/10.1021/ja00071a009