Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ursula M. Talbot"'
Autor:
Jonas Lofling, Hai Yu, Nissi Varki, Shengshu Huang, James C. Paton, Travis Clarke Beddoe, Matthew C.J. Wilce, David F. Smith, Jamie Rossjohn, Damien C. Chong, Ajit Varki, Ursula M. Talbot, Xi Chen, Adrienne W. Paton, Emma Byres
Publikováno v:
Monash University
AB(5) toxins comprise an A subunit that corrupts essential eukaryotic cell functions, and pentameric B subunits that direct target-cell uptake after binding surface glycans. Subtilase cytotoxin (SubAB) is an AB(5) toxin secreted by Shiga toxigenic Es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ba9ed5389034f8513e370d87d8edfa
https://doi.org/10.1038/nature07428
https://doi.org/10.1038/nature07428
Autor:
Jamie Rossjohn, Matthew C.J. Wilce, Adrienne W. Paton, James C. Paton, Cheleste M. Thorpe, James C. Whisstock, Ursula M. Talbot, Travis Clarke Beddoe
Publikováno v:
Nature. 443:548-552
AB5 toxins are produced by pathogenic bacteria and consist of enzymatic A subunits that corrupt essential eukaryotic cell functions, and pentameric B subunits that mediate uptake into the target cell. AB5 toxins include the Shiga, cholera and pertuss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcdc71879f708588847943bb3587dae8
https://doi.org/10.1038/nature05124
https://doi.org/10.1038/nature05124
Publikováno v:
Infection and Immunity. 74:1962-1966
The contribution of flagellin to the virulence of the O113:H21 Shiga-toxigenic Escherichia coli (STEC) strain 98NK2 was investigated in the streptomycin-treated mouse model. Groups of mice were challenged with either the wild-type STEC or a fliC dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c89c533feda1039ac152a51795b47fa
https://doi.org/10.1128/iai.74.3.1962-1966.2006
https://doi.org/10.1128/iai.74.3.1962-1966.2006
Publikováno v:
The Journal of Experimental Medicine
The Shiga toxigenic Escherichia coli (STEC) O113:H21 strain 98NK2, which was responsible for an outbreak of hemolytic uremic syndrome, secretes a highly potent and lethal subtilase cytotoxin that is unrelated to any bacterial toxin described to date.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189044853a1a842e25244f0acdea48d1
https://doi.org/10.1084/jem.20040392
https://doi.org/10.1084/jem.20040392
We have recently described a novel AB 5 cytotoxin produced by certain Shiga toxin-producing Escherichia coli strains. The A subunit of this toxin is a subtilase-like serine protease, while the B pentamer mediates binding to host cell glycolipid recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d91368335d2f75a50bf502e8c2acb6
https://europepmc.org/articles/PMC1168599/
https://europepmc.org/articles/PMC1168599/
