Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ursula Kern"'
Autor:
Ursula Kern, Klemens Fröhlich, Johanna Bedacht, Nico Schmidt, Martin L. Biniossek, Nicole Gensch, Katja Baerenfaller, Oliver Schilling
Publikováno v:
Cells, Vol 10, Iss 2, p 404 (2021)
DJ-1 is an abundant and ubiquitous component of cellular proteomes. DJ-1 supposedly exerts a wide variety of molecular functions, ranging from enzymatic activities as a deglycase, protease, and esterase to chaperone functions. However, a consensus pe
Externí odkaz:
https://doaj.org/article/392ba20d4d084173b9fb52f8e1cc511e
Autor:
Frank Bühling, Martin Kouadio, Caroline E Chwieralski, Ursula Kern, Jens M Hohlfeld, Nicole Klemm, Nicole Friedrichs, Wera Roth, Jan M Deussing, Christoph Peters, Thomas Reinheckel
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26247 (2011)
BackgroundThe 11 human cysteine cathepsins are proteases mainly located in the endolysosomal compartment of all cells and within the exocytosis pathways of some secretory cell types. Cathepsin H (Ctsh) has amino- and endopeptidase activities. In vitr
Externí odkaz:
https://doaj.org/article/d5488f2d2d71445f9c6cd12707cc41c7
Autor:
Luis Zanon Rodriguez, Ursula Kern, Franziska Theilig, Ina Maria Schiessl, Jean Luc Magnin, Eileen Dahlke, Géraldine Mollet, Oliver Schilling, Alexey Larionov, Madlen Kunke, Hayo Castrop, Abdel A. Alli
Publikováno v:
Journal of Cellular and Molecular Medicine
The NPHS2 gene, encoding the slit diaphragm protein podocin, accounts for genetic and sporadic forms of nephrotic syndrome (NS). Patients with NS often present symptoms of volume retention, such as oedema formation or hypertension. The primary dysreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7a4c3c4ea8fdb46dd852b48ba97699
http://doc.rero.ch/record/327433/files/lar_cbi.pdf
http://doc.rero.ch/record/327433/files/lar_cbi.pdf
Autor:
Mathias Hohl, Ursula Kern, Dominik Linz, Alejandro Gomez-Auli, Johann Gassenhuber, Oliver Schilling, Agnese Petrera, Thorsten Sadowski
Publikováno v:
Journal of Proteome Research. 15:3188-3195
Cathepsin A (CTSA) is a lysosomal carboxypeptidase present at the cell surface and secreted outside the cell. Additionally, CTSA binds to β-galactosidase and neuraminidase 1 to protect them from degradation. CTSA has gained attention as a drug targe
Autor:
Chi Bin Chien, Joern Schweitzer, Joshua L. Bonkowsky, Ursula Kern, Edda Kastenhuber, Wolfgang Driever
Publikováno v:
Journal of Neuroscience. 29:8914-8926
Longitudinal axons provide connectivity between remote areas of the nervous system. Although the molecular determinants driving commissural pathway formation have been well characterized, mechanisms specifying the formation of longitudinal axon tract
Autor:
Ursula, Kern, Vladimir, Wischnewski, Martin L, Biniossek, Oliver, Schilling, Thomas, Reinheckel
Publikováno v:
Molecular Cancer
Background Normal epithelial cells and carcinoma cells can acquire invasiveness by epithelial-to-mesenchymal transition (EMT), a process of considerable cellular remodeling. The endosomal/lysosomal compartment is a principal site of intracellular pro
Autor:
Ursula Kern
Publikováno v:
Feministische Studien. 15:80-87
Autor:
Sira C. Günther, Mansoureh Sameni, J R Seiz, Bonnie F. Sloane, Lisa Sevenich, Dietmar Pfeifer, Marlene Tacke, Fee Bengsch, Christoph Peters, D. von Elverfeldt, Ursula Kern, Thomas Reinheckel, Achim Buck, Larissa E. Hillebrand
Publikováno v:
Oncogene. 33(36)
The cysteine protease cathepsin B (CTSB) is frequently overexpressed in human breast cancer and correlated with a poor prognosis. Genetic deficiency or pharmacological inhibition of CTSB attenuates tumor growth, invasion and metastasis in mouse model
Publikováno v:
Proteases: Structure and Function ISBN: 9783709108840
The generation of genetically engineered mouse models (GEM) allows studying the effects of deleting, mutating, or overexpressing proteases and their endogenous inhibitors in a complex living organism. During the past decade this approach has been wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36ce380d3d85c6d29e32e77bce7ead99
https://doi.org/10.1007/978-3-7091-0885-7_6
https://doi.org/10.1007/978-3-7091-0885-7_6
Autor:
Ursula Kern
Publikováno v:
Macht des Vertrauens ISBN: 9783834944528
The trustworthiness of financial statements is crucial for economic behaviour of all actors involved. Without the presumption of a true and fair display of a company’s financial situation trade is made more and more difficult – especially when li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b1e9a37780983950b1745466f1f3a18
https://doi.org/10.1007/978-3-8349-4453-5_7
https://doi.org/10.1007/978-3-8349-4453-5_7