Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ursula K Rohlwink"'
Autor:
Nicholas W Loxton, Ursula K Rohlwink, Mvuwo Tshavhungwe, Lindizwe Dlamini, Muki Shey, Nico Enslin, Anthony Figaji
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0246997 (2021)
Tuberculous meningitis (TBM) is the most fatal form of tuberculosis and frequently occurs in children. The inflammatory process initiates secondary brain injury processes that lead to death and disability. Much remains unknown about this cerebral inf
Externí odkaz:
https://doaj.org/article/5f51879a6e72484c8806b4a4571c6cf4
Autor:
Ursula K Rohlwink, Felicia C Chow, Sean Wasserman, Sofiati Dian, Rachel PJ Lai, Lidya Chaidir, Raph L Hamers, Robert J Wilkinson, David R Boulware, Fiona V Cresswell, Arjan van Laarhoven, Tuberculous Meningitis International Research Consortium
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Tuberculous meningitis (TBM), the most severe manifestation of tuberculosis, has poorly understood immunopathology and high mortality and morbidity despite antituberculous therapy. This calls for accelerated clinical and basic science research in thi
Externí odkaz:
https://doaj.org/article/8f8ef9921dce440e87c81b8c9c0901f3
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/3f38821f6eaf47988003b3c7cf76c889
Autor:
Tatiana Barichello, Carlos Henrique Rocha Catalão, Ursula K. Rohlwink, Martijn van der Kuip, Dan Zaharie, Regan S. Solomons, Ronald van Toorn, Marceline Tutu van Furth, Rodrigo Hasbun, Federico Iovino, Vivian Ssonko Namale
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Bacterial meningitis differs globally, and the incidence and case fatality rates vary by region, country, pathogen, and age group; being a life-threatening disease with a high case fatality rate and long-term complications in low-income countries. Af
Externí odkaz:
https://doaj.org/article/0ca69cfc2bce43a2b61bec7d53dc3956
Autor:
Claudia A. Smith, Ursula K. Rohlwink, Katya Mauff, Nqobile S. Thango, Thembani S. Hina, Shamiel Salie, Johannes M. N. Enslin, Anthony A. Figaji
Publikováno v:
Critical Care Medicine, 51(5), 573-583. Lippincott Williams & Wilkins
OBJECTIVES: To examine cerebrovascular pressure reactivity index (PRx) in a large cohort of children with severe traumatic brain injury (sTBI) in association with physiologic variables and outcome. DESIGN: Retrospective observational cohort study. SE
Autor:
J.M.N. Enslin, Nqobile S Thango, Anthony Figaji, Lindizwe Dlamini, M. Phophi Tshavhungwe, Ursula K. Rohlwink, Shamiel Salie, E. Banderker
Publikováno v:
Child's Nervous System. 37:1713-1721
A better understanding of the complex pathophysiology of traumatic brain injury (TBI) is needed to improve our current therapies. Cerebral microdialysis (CMD) is an advanced method to monitor the brain, but little is known about its parameters in chi
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
Frontiers in Neurology
Frontiers in Neurology
Central nervous system (CNS) infections remain a major burden of pediatric disease associated with significant long-term morbidity due to injury to the developing brain. Children are susceptible to various etiologies of CNS infection partly because o
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Central nervous system (CNS) infections occur more commonly in young children than in adults and pose unique challenges in the developing brain. This review builds on the distinct vulnerabilities in children's peripheral immune system (outlined in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a01e98de8082545221e6b3041452ed
Autor:
Armin Deffur, Abdul Karim Sesay, Regan Solomons, Nico Enslin, Ursula K. Rohlwink, Robert J. Wilkinson, Michael Levin, Ronald van Toorn, Katalin A. Wilkinson, Stuart Horswell, Rachel P. J. Lai, Anthony Figaji, Brian Eley
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Nature Communications
Nature Communications
Tuberculous meningitis (TBM) is the most severe form of TB with high rates of mortality and morbidity. Here we conduct RNA-sequencing on whole blood as well as on ventricular and lumbar cerebrospinal fluid (CSF) of pediatric patients treated for TBM.