Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ursula Engels"'
Autor:
Johanna Maria Hölken, Katja Friedrich, Marion Merkel, Nelli Blasius, Ursula Engels, Timo Buhl, Karsten Rüdiger Mewes, Lars Vierkotten, Nicole Elisabeth Teusch
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
We have integrated dermal dendritic cell surrogates originally generated from the cell line THP-1 as central mediators of the immune reaction in a human full-thickness skin model. Accordingly, sensitizer treatment of THP-1-derived CD14-, CD11c+ immat
Externí odkaz:
https://doaj.org/article/2e89d2a84ff349b7a4adb2e337559cd8
Publikováno v:
ALTEX. 38(1)
Cosmetic ingredients must be toxicologically assessed to determine their skin sensitizing potential. The in vitro human cell line activation test (h-CLAT; OECD TG 442E) addresses the activation of dermal dendritic cells by analyzing specific protein
Autor:
Andreas Schepky, Klaus-Peter Wittern, Walter Diembeck, Wolfgang Pape, Silke Gerlach, Kerstin Reisinger, Horst Wenck, Jochem Spieker, Ursula Engels, Hendrik Reuter, Ludger Kolbe, Robert Dr. Schmucker
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 25(1)
Allergic contact dermatitis is a delayed T-cell mediated allergic response associated with relevant social and economic impacts. Animal experiments (e.g. the local lymph node assay) are still supplying most of the data used to assess the sensitizatio