Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ursula B. McGovern"'
Supplementary Fig. S1 from Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer
Autor:
Eric W-F. Lam, R. Charles Coombes, Andreas Polychronis, Jimmy M-M. Kwok, Janna Krol, Stephen S. Myatt, Jun Wang, Stephanie K. Guest, Barrie Peck, Richard E. Francis, Ursula B. McGovern
Supplementary Fig. S1 from Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86252130ef627516354c6d9b135f58bd
https://doi.org/10.1158/1535-7163.22485026
https://doi.org/10.1158/1535-7163.22485026
Supplementary Fig. S3 from Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer
Autor:
Eric W-F. Lam, R. Charles Coombes, Andreas Polychronis, Jimmy M-M. Kwok, Janna Krol, Stephen S. Myatt, Jun Wang, Stephanie K. Guest, Barrie Peck, Richard E. Francis, Ursula B. McGovern
Supplementary Fig. S3 from Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0812b2ab66b70e767cf71a4693aad357
https://doi.org/10.1158/1535-7163.22485017
https://doi.org/10.1158/1535-7163.22485017
Autor:
Eric W-F. Lam, R. Charles Coombes, Andreas Polychronis, Jimmy M-M. Kwok, Janna Krol, Stephen S. Myatt, Jun Wang, Stephanie K. Guest, Barrie Peck, Richard E. Francis, Ursula B. McGovern
Gefitinib (Iressa) is a specific and effective epidermal growth factor receptor inhibitor. An understanding of the downstream cellular targets of gefitinib will allow the discovery of biomarkers for predicting outcomes and monitoring anti-epidermal g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c787fc79d949ac7b71cebe55bc44f028
https://doi.org/10.1158/1535-7163.c.6531728
https://doi.org/10.1158/1535-7163.c.6531728
Supplementary Fig. S2 from Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer
Autor:
Eric W-F. Lam, R. Charles Coombes, Andreas Polychronis, Jimmy M-M. Kwok, Janna Krol, Stephen S. Myatt, Jun Wang, Stephanie K. Guest, Barrie Peck, Richard E. Francis, Ursula B. McGovern
Supplementary Fig. S2 from Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b44a7579957ff1e3a70308735617bc
https://doi.org/10.1158/1535-7163.22485020.v1
https://doi.org/10.1158/1535-7163.22485020.v1
Autor:
Ursula B. McGovern, Richard E. Francis, Stephanie K. Guest, Andreas Polychronis, Janna Krol, R. Charles Coombes, Jimmy M.-M. Kwok, Jun Wang, Stephen S. Myatt, Barrie Peck, Eric Lam
Publikováno v:
Molecular Cancer Therapeutics. 8:582-591
Gefitinib (Iressa) is a specific and effective epidermal growth factor receptor inhibitor. An understanding of the downstream cellular targets of gefitinib will allow the discovery of biomarkers for predicting outcomes and monitoring anti-epidermal g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1108568f3875f25d2c49278f1def16bd
https://doi.org/10.1158/1535-7163.mct-08-0805
https://doi.org/10.1158/1535-7163.mct-08-0805
Autor:
Eric Lam, Chuay-Yeng Koo, Ursula B. McGovern, J. Simon C. Arthur, Ka-Kei Ho, Angel R. Nebreda, Douglas J. Kelly, Natalia de Olano, David G. Campbell, Evie Maifoshie, Kyle W. Muir, Ana R. Gomes, Victoria A. McGuire, Lara J. Monteiro
Publikováno v:
The Journal of biological chemistry. 287(2)
FOXO3a is a forkhead transcription factor that regulates a multitude of important cellular processes, including proliferation, apoptosis, differentiation, and metabolism. Doxorubicin treatment of MCF-7 breast carcinoma cells results in FOXO3a nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc12c192749073968cbe398153f5c84f
https://pubmed.ncbi.nlm.nih.gov/22128155
https://pubmed.ncbi.nlm.nih.gov/22128155
Autor:
Qunyan Yu, Eric Lam, Jun Wang, Stephanie K. Guest, David Peston, R. Charles Coombes, O Gojis, Janna Krol, Richard E. Francis, Piotr Sicinski, Ursula B. McGovern, Barrie Peck, Carlo Palmieri, Sami Shousha, Johan Hartman, Stephen S. Myatt, Aleksandra Filipovic
Publikováno v:
International journal of oncology. 35(1)
The tyrosine kinase receptor, HER2 is a crucial prognostic marker and therapeutic target for breast cancer; however, the downstream targets and biological effectors of HER2 remain unclear. We investigated the relationship between HER2 and the transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf60c262387d62863baf70c7fafe476
https://pubmed.ncbi.nlm.nih.gov/19513552
https://pubmed.ncbi.nlm.nih.gov/19513552
Autor:
Abdelkader, Essafi, Ana R, Gomes, Karen M, Pomeranz, Aleksandra K, Zwolinska, Rana, Varshochi, Ursula B, McGovern, Eric W-F, Lam
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 462
This chapter describes methods for studying downstream events of the PI3K/Akt signaling cascade, focusing on the FoxO transcription factors. These approaches also represent alternative means for gauging the phosphoinositide-3 kinase/Akt activity. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1496e820df370ca423e9db1c4f4d03d2
https://pubmed.ncbi.nlm.nih.gov/19160671
https://pubmed.ncbi.nlm.nih.gov/19160671
Autor:
Eric Lam, Aleksandra K. Zwolinska, Karen M. Pomeranz, Rana Varshochi, Ana R. Gomes, Abdelkader Essafi, Ursula B. McGovern
Publikováno v:
Methods in Molecular Biology ISBN: 9781588297273
This chapter describes methods for studying downstream events of the PI3K/Akt signaling cascade, focusing on the FoxO transcription factors. These approaches also represent alternative means for gauging the phosphoinositide-3 kinase/Akt activity. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcbd5f1d70b57e23a31ab964efde9f70
https://doi.org/10.1007/978-1-60327-115-8_13
https://doi.org/10.1007/978-1-60327-115-8_13