Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Ursula, Quitterer"'
Autor:
Joshua Abd Alla, Ursula Quitterer
Publikováno v:
Cells, Vol 11, Iss 4, p 654 (2022)
The RAF kinase inhibitor protein, RKIP, is a dual inhibitor of the RAF1 kinase and the G protein-coupled receptor kinase 2, GRK2. By inhibition of the RAF1-MAPK (mitogen-activated protein kinase) pathway, RKIP acts as a beneficial tumour suppressor.
Externí odkaz:
https://doaj.org/article/46322e8c391a41fcbbc906f4f9f798ea
Autor:
Ursula Quitterer, Said AbdAlla
Publikováno v:
Cells, Vol 10, Iss 10, p 2609 (2021)
Preeclampsia is one of the most frequent and severe complications of pregnancy. Symptoms of preeclampsia usually occur after 20 weeks of pregnancy and include hypertension and kidney dysfunction with proteinuria. Up to now, delivery of the infant has
Externí odkaz:
https://doaj.org/article/2d1e6eb9169d4d1fbea9a3b3f3c94f76
Autor:
Alexander Perhal, Stefan Wolf, Yahya F. Jamous, Andreas Langer, Joshua Abd Alla, Ursula Quitterer
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Atherosclerosis and ensuing cardiovascular disease are major causes of death with insufficient treatment options. In search for pathomechanisms of atherosclerosis, we investigated the impact of the B2 bradykinin receptor, Bdkrb2, on atherosclerotic l
Externí odkaz:
https://doaj.org/article/57445ea9003047c690f20ed415d0004a
Publikováno v:
Frontiers in Medicine, Vol 5 (2019)
Inhibition of the G-protein-coupled receptor kinase 2 (GRK2) is an emerging treatment approach for heart failure. Therefore, cardio-protective mechanisms induced by GRK2 inhibition are under investigation. We compared two different GRK2 inhibitors, i
Externí odkaz:
https://doaj.org/article/b37254d42f934c82b7a790fd443bcc5e
Autor:
Ursula Quitterer, Said AbdAlla
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
The family of G-protein-coupled receptors (GPCRs) is one of the most important drug targets. Mechanisms underlying GPCR activation and signaling are therefore of great pharmacologic interest. It was long thought that GPCRs exist and function as monom
Externí odkaz:
https://doaj.org/article/8abc9624a0ff480e8bb60fef55ae9f0f
Autor:
Alexander, Perhal, Stefan, Wolf, Yahya F, Jamous, Andreas, Langer, Joshua, Abd Alla, Ursula, Quitterer
Publikováno v:
Frontiers in Medicine
Atherosclerosis and ensuing cardiovascular disease are major causes of death with insufficient treatment options. In search for pathomechanisms of atherosclerosis, we investigated the impact of the B2 bradykinin receptor, Bdkrb2, on atherosclerotic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e40af2e5bd35685c4e440aa00407eed
https://pubmed.ncbi.nlm.nih.gov/30847343
https://pubmed.ncbi.nlm.nih.gov/30847343
Publikováno v:
Journal of Biological Chemistry
Impairment of myocardial fatty acid substrate metabolism is characteristic of late-stage heart failure and has limited treatment options. Here, we investigated whether inhibition of G-protein-coupled receptor kinase 2 (GRK2) could counteract the dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c9f95987a6b0cd15c0f9feb028c381
https://doi.org/10.1074/jbc.m115.702688
https://doi.org/10.1074/jbc.m115.702688
Autor:
Ursula Quitterer, Said AbdAlla
Publikováno v:
Pharmacological Research. 154:104230
With ageing of the global society, the frequency of ageing-related neurodegenerative diseases such as Alzheimer`s disease (AD) is on the rise worldwide. Currently, there is no cure for AD, and the four drugs approved for AD only have very small effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ad3cf77e588d6cec08545f0b6c7bae
https://doi.org/10.1016/j.phrs.2019.04.014
https://doi.org/10.1016/j.phrs.2019.04.014
Autor:
Ursula Quitterer, Muriel Graemer
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 388:1-98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc2a9de14315cee73f0a2568430abb56
https://doi.org/10.1007/s00210-015-1087-4
https://doi.org/10.1007/s00210-015-1087-4
Autor:
Ursula Quitterer, Said AbdAlla
Publikováno v:
Biochemical pharmacology, 88 (3)
Biochemical Pharmacology
Biochemical Pharmacology
The AT1 receptor for the vasopressor angiotensin II is one of the most important drug targets for the treatment of cardiovascular diseases. Sensitization of the AT1 receptor system is a common feature contributing to the pathogenesis of many cardiova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712f4feb360e0271589a2d516c28c9b5