Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Ursula, Greferath"'
Autor:
Josephine H. C. Wong, Jessica Y. W. Ma, Andrew I. Jobling, Alice Brandli, Ursula Greferath, Erica L. Fletcher, Kirstan A. Vessey
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the older population. Classical hallmarks of early and intermediate AMD are accumulation of drusen, a waste deposit formed under the retina, and pigmentary abnor
Externí odkaz:
https://doaj.org/article/7a461a36e84249eebe75654648f35fae
Autor:
Jessica Y.W. Ma, Ursula Greferath, Josephine H.C. Wong, Linda J. Fothergill, Andrew I. Jobling, Kirstan A. Vessey, Erica L. Fletcher
Publikováno v:
Neurobiology of Aging. 128:1-16
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Microglia, the resident immune cells of the central nervous system (CNS), were once considered quiescent cells that sat in readiness for reacting to disease and injury. Over the last decade, however, it has become clear that microglia play essential
Externí odkaz:
https://doaj.org/article/27dc90e2fdd44d4794e7b062efd1d495
Autor:
Kiana Kakavand, Andrew I. Jobling, Ursula Greferath, Kirstan A. Vessey, Robb U. de Iongh, Erica L. Fletcher
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Photoreceptor death contributes to 50% of irreversible vision loss in the western world. Pro23His (P23H) transgenic albino rat strains are widely used models for the most common rhodopsin gene mutation associated with the autosomal dominant form of r
Externí odkaz:
https://doaj.org/article/6f4169eef20540858345535f0fb8a25b
Autor:
Kirstan A Vessey, Andrew I Jobling, Mai X. Tran, Anna Y. Wang, Ursula Greferath, Erica L. Fletcher
Publikováno v:
Autophagy. 18:2368-2384
Age-related macular degeneration (AMD) is a leading cause of vision loss with recent evidence indicating an important role for macroautophagy/autophagy in disease progression. In this study we investigate the efficacy of targeting autophagy for slowi
Autor:
Kirstan A. Vessey, Anna Ym Wang, Bang V. Bui, Quan Findlay, Andrew I Jobling, Alice Brandli, Michael A Dixon, Ursula Greferath, Erica L. Fletcher, Pei Ying Lee
Publikováno v:
Clinical and Experimental Optometry. 103:562-571
Glaucoma is a neurodegenerative disease characterised by progressive damage to the retinal ganglion cells (RGCs), the output neurons of the retina. RGCs are a heterogenous class of retinal neurons which can be classified into multiple types based on
Autor:
Elena Ivanova, Connie H Wong, Bang V. Bui, Gene Venables, Samuel A Mills, Michael A Dixon, Flora Hui, Zheng He, Kirstan A. Vessey, Vickie Hy Wong, Josh Tonc, James C Young, Botir T. Sagdullaev, Andrew I Jobling, Ursula Greferath, Erica L. Fletcher, Joanna A. Phipps
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance This work identifies a role for microglia, the innate immune cells of the CNS, in the local control of the retinal vasculature and identifies deficits early in diabetes. Microglia contact neurons and vasculature and express several vasoa
Publikováno v:
Progress in retinal and eye research. 88
Reticular pseudodrusen (RPD), or subretinal drusenoid deposits (SDD), refer to distinct lesions that occur in the subretinal space. Over the past three decades, their presence in association with age-related macular degeneration (AMD) has become incr
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Microglia, the resident immune cells of the central nervous system (CNS), were once considered quiescent cells that sat in readiness for reacting to disease and injury. Over the last decade, however, it has become clear that microglia play essential
Autor:
Ursula Greferath, Kirstan A Vessey, Andrew I Jobling, Samuel A Mills, Bang V Bui, Zheng He, Nupur Nag, Hiroshi Ohtsu, Erica L Fletcher
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116025 (2014)
The role of histamine in the retina is not well understood, despite it regulating a number of functions within the brain, including sleep, feeding, energy balance, and anxiety. In this study we characterized the structure and function of the retina i
Externí odkaz:
https://doaj.org/article/6e78cf7f2c9444959fbd3439049cb7de