Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Ursula, Creutzig"'
Autor:
Marius Flasinski, Kira Scheibke, Martin Zimmermann, Ursula Creutzig, Katarina Reinhardt, Femke Verwer, Valerie de Haas, Vincent H.J. van der Velden, Christine von Neuhoff, C. Michel Zwaan, Dirk Reinhardt, Jan-Henning Klusmann
Publikováno v:
Blood Advances, Vol 2, Iss 13, Pp 1532-1540 (2018)
Abstract: Approximately 5% to 10% of children with Down syndrome (DS) are diagnosed with transient myeloproliferative disorder (TMD). Approximately 20% of these patients die within 6 months (early death), and another 20% to 30% progress to myeloid le
Externí odkaz:
https://doaj.org/article/51672d643559410a9f68e6fc94eba776
Autor:
Naghmeh Niktoreh, Beate Lerius, Martin Zimmermann, Bernd Gruhn, Gabriele Escherich, Jean-Pierre Bourquin, Michael Dworzak, Lucie Sramkova, Claudia Rossig, Ursula Creutzig, Dirk Reinhardt, Mareike Rasche
Publikováno v:
Haematologica, Vol 104, Iss 1 (2019)
Despite intensified salvage treatments, children with relapsed/refractory acute myeloid leukemia (AML) have poor survival. We evaluated gemtuzumab ozogamicin (CD33-targeted drug) used on a compassionate basis in patients diagnosed from 1995 until 201
Externí odkaz:
https://doaj.org/article/87abc21689c54a8390b3dbb1c975961a
Autor:
Gabriele Gauß, Sabine Kesting, Ursula Creutzig, Freerk Baumann, Joachim Boos, Uta Dirksen, Katharina Eckert, Robert Erschig, Pablo Hernáiz Driever, Ingo Menrath, Aram Prokop, Dominik Schneider, Jannos Siaplaouras, Hannah Stalf, Arne Streitbürger, Andreas Wiener, Joachim Wiskemann, Torge Wittke, Miriam Götte
Publikováno v:
Monatsschrift Kinderheilkunde. 170:548-550
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8634c5baf9b24ac9ac5fceb493e1fddf
https://doi.org/10.1007/s00112-022-01474-z
https://doi.org/10.1007/s00112-022-01474-z
Autor:
Christine von Neuhoff, Dirk Reinhardt, Yves Bertrand, Kim Klein, Sarah Elitzur, Jonas Abrahamsson, Guy Leverger, Jacqueline Cloos, Ursula Creutzig, Valerie de Haas, Romy E. Van Weelderen, Pter Smisek, Martin Zimmermann, Henrik Hasle, Brenda Gibson, Alcira Fynn, Bassem I. Razzouk, Alexei Maschan, Shau Yin Ha, Michael Dworzak, Christine J. Harrison, H. Berna Beverloo, Carmelo Rizzari, Gertjan J.L. Kaspers, Susana C. Raimondi
Publikováno v:
Pediatric Blood and Cancer, 69(1):e29341. Wiley-Liss Inc.
Klein, K, Beverloo, H B, Zimmermann, M, Raimondi, S C, von Neuhoff, C, de Haas, V, van Weelderen, R, Cloos, J, Abrahamsson, J, Bertrand, Y, Dworzak, M, Fynn, A, Gibson, B, Ha, S Y, Harrison, C J, Hasle, H, Elitzur, S, Leverger, G, Maschan, A, Razzouk, B, Reinhardt, D, Rizzari, C, Smisek, P, Creutzig, U & Kaspers, G J L 2022, ' Prognostic significance of chromosomal abnormalities at relapse in children with relapsed acute myeloid leukemia : A retrospective cohort study of the Relapsed AML 2001/01 Study ', Pediatric Blood and Cancer, vol. 69, no. 1, e29341 . https://doi.org/10.1002/pbc.29341
Klein, K, Beverloo, H B, Zimmermann, M, Raimondi, S C, von Neuhoff, C, de Haas, V, van Weelderen, R, Cloos, J, Abrahamsson, J, Bertrand, Y, Dworzak, M, Fynn, A, Gibson, B, Ha, S-Y, Harrison, C J, Hasle, H, Elitzur, S, Leverger, G, Maschan, A, Razzouk, B, Reinhardt, D, Rizzari, C, Smisek, P, Creutzig, U & Kaspers, G J L 2022, ' Prognostic significance of chromosomal abnormalities at relapse in children with relapsed acute myeloid leukemia : A retrospective cohort study of the Relapsed AML 2001/01 Study ', Pediatric Blood & Cancer, vol. 69, no. 1, e29341 . https://doi.org/10.1002/pbc.29341
Klein, K, Beverloo, H B, Zimmermann, M, Raimondi, S C, von Neuhoff, C, de Haas, V, van Weelderen, R, Cloos, J, Abrahamsson, J, Bertrand, Y, Dworzak, M, Fynn, A, Gibson, B, Ha, S Y, Harrison, C J, Hasle, H, Elitzur, S, Leverger, G, Maschan, A, Razzouk, B, Reinhardt, D, Rizzari, C, Smisek, P, Creutzig, U & Kaspers, G J L 2022, ' Prognostic significance of chromosomal abnormalities at relapse in children with relapsed acute myeloid leukemia : A retrospective cohort study of the Relapsed AML 2001/01 Study ', Pediatric Blood and Cancer, vol. 69, no. 1, e29341 . https://doi.org/10.1002/pbc.29341
Klein, K, Beverloo, H B, Zimmermann, M, Raimondi, S C, von Neuhoff, C, de Haas, V, van Weelderen, R, Cloos, J, Abrahamsson, J, Bertrand, Y, Dworzak, M, Fynn, A, Gibson, B, Ha, S-Y, Harrison, C J, Hasle, H, Elitzur, S, Leverger, G, Maschan, A, Razzouk, B, Reinhardt, D, Rizzari, C, Smisek, P, Creutzig, U & Kaspers, G J L 2022, ' Prognostic significance of chromosomal abnormalities at relapse in children with relapsed acute myeloid leukemia : A retrospective cohort study of the Relapsed AML 2001/01 Study ', Pediatric Blood & Cancer, vol. 69, no. 1, e29341 . https://doi.org/10.1002/pbc.29341
BACKGROUND: In addition to treatment response, cytogenetic and molecular aberrations are the most important prognostic factors in children with de novo acute myeloid leukemia (AML). However, little is known about cytogenetics at the time of relapse.M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803fea05029ddfdbff93d7ee929a6a32
https://www.ncbi.nlm.nih.gov/pubmed/34532968
https://www.ncbi.nlm.nih.gov/pubmed/34532968
Autor:
Costa Bachas, Gerrit Jan Schuurhuis, C Michel Zwaan, Marry M van den Heuvel-Eibrink, Monique L den Boer, Eveline S J M de Bont, Zinia J Kwidama, Dirk Reinhardt, Ursula Creutzig, Valérie de Haas, Gertjan J L Kaspers, Jacqueline Cloos
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121730 (2015)
Development of relapse remains a problem for further improvements in the survival of pediatric AML patients. While virtually all patients show a good response to initial treatment, more patients respond poorly when treated at relapse. The cellular ch
Externí odkaz:
https://doaj.org/article/f2c2fd5f271c447aa5b3df572240735c
Autor:
Ursula Creutzig, Marius Flasinski, Richard Golnik, Jan-Henning Klusmann, Katharina Waack, Sina Al-Kershi, Michael Dworzak, Dirk Reinhardt, Mareike Rasche
Publikováno v:
Klinische Padiatrie. 233(6)
Children with Down syndrome are at a high risk of developing transient abnormal myelopoiesis (TAM; synonym: TMD) or myeloid leukemia (ML-DS). While most patients with TAM are asymptomatic and go into spontaneous remission without a need for therapy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fccedf54d80f1158c6fa40b0d72bc9e
https://pubmed.ncbi.nlm.nih.gov/34407551
https://pubmed.ncbi.nlm.nih.gov/34407551
Autor:
Jan-Henning Klusmann, Ursula Creutzig, Katharina Waack, Mareike Rasche, Michael C. Frühwald, Katharina Jansen, Gabriele Escherich, Christiane Walter, Dirk Reinhardt, Michael Dworzak, Markus Schneider, Heidrun Boztug
Publikováno v:
Blood. 136:12-14
Introduction Over the past 40 years, therapy intensification has continuously contributed to an improvement in the prognosis of children with AML. Hence, the AML-BFM 2004 trial resulted in a 5-year overall survival rate (OS) of 70%. Similar outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdf87bf350209595f37213aafb874f49
https://doi.org/10.1182/blood-2020-139189
https://doi.org/10.1182/blood-2020-139189
Autor:
Ursula Creutzig, Martin Zimmermann, Michael N. Dworzak, Brenda Gibson, Rienk Tamminga, Jonas Abrahamsson, Shau-Yin Ha, Henrik Hasle, Alexey Maschan, Yves Bertrand, Guy Leverger, Christine von Neuhoff, Bassem Razzouk, Carmelo Rizzari, Petr Smisek, Owen P. Smith, Batia Stark, Dirk Reinhardt, Gertjan L. Kaspers
Publikováno v:
Haematologica, Vol 99, Iss 9 (2014)
The prognostic significance of early response to treatment has not been reported in relapsed pediatric acute myeloid leukemia. In order to identify an early and easily applicable prognostic factor allowing subsequent treatment modifications, we asses
Externí odkaz:
https://doaj.org/article/1665833acc1248498f4128737c2867b0
Autor:
Nora Muehlegger, Ursula Creutzig, Emma Steidel, Jan Stary, Dirk Reinhardt, Lucie Sramkova, Christiane Walter, Naghmeh Niktoreh, Nils von Neuhoff, Heidrun Boztug, Thomas Lehrnbecher, Jean-Pierre Bourquin, Michael Dworzak, Iveta Janotova, Mareike Rasche, Martin Zimmermann, Edward A. Kolb
Publikováno v:
Cancers, Vol 13, Iss 789, p 789 (2021)
Cancers
Volume 13
Issue 4
Cancers
Volume 13
Issue 4
Successful management of relapse is critical to improve outcomes of children with acute myeloid leukemia (AML). We evaluated response, survival and prognostic factors after a second relapse of AML. Among 1222 pediatric patients of the population-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90173760db6dc24a9f98249fddf7de1e
https://pubmed.ncbi.nlm.nih.gov/33672815
https://pubmed.ncbi.nlm.nih.gov/33672815
Autor:
Ursula Creutzig, Dirk Reinhardt
Publikováno v:
Springer Reference Medizin ISBN: 9783662467640
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06b774e3f021a5c36396f02032cd439c
https://doi.org/10.1007/978-3-662-46764-0_12-1
https://doi.org/10.1007/978-3-662-46764-0_12-1