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Autor:
Siegfried R. Waldvogel, Till Opatz, Georg Steinkellner, Margit Winkler, Helmut Schwab, Karl Gruber, Alexander M. Nauth, Urska Pogorevcnik, Birgit Grill, Kai Donsbach, Sebastian Arndt, Dominik Weis
Publikováno v:
Green Chemistry. 23:388-395
Levetiracetam is an active pharmaceutical ingredient widely used to treat epilepsy. We describe a new synthesis of levetiracetam by a dynamic kinetic resolution and a ruthenium-catalysed ex-cell anodic oxidation. For the enzymatic resolution, we tail