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Autor:
Anders Rane, Margarita G. Ladona, Kerstin Persson, Urs M Zanger, Örjan Mortimer, David Spalding, Urs A Meyer
Publikováno v:
Clinical Pharmacology and Therapeutics. 47:27-35
We studied the oxidation capacity in liver biopsies of a series of extensive metabolizers (n = 10) and poor metabolizers (n = 2) as identified by in vivo phenotyping with dextromethorphan. Codeine and dextromethorphan were used as probe drugs in vitr