Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Urs, Heilbronner"'
Distinct genetic liability profiles define clinically relevant patient strata across common diseases
Autor:
Lucia Trastulla, Georgii Dolgalev, Sylvain Moser, Laura T. Jiménez-Barrón, Till F. M. Andlauer, Moritz von Scheidt, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Monika Budde, Urs Heilbronner, Sergi Papiol, Alexander Teumer, Georg Homuth, Henry Völzke, Marcus Dörr, Peter Falkai, Thomas G. Schulze, Julien Gagneur, Francesco Iorio, Bertram Müller-Myhsok, Heribert Schunkert, Michael J. Ziller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-28 (2024)
Abstract Stratified medicine holds great promise to tailor treatment to the needs of individual patients. While genetics holds great potential to aid patient stratification, it remains a major challenge to operationalize complex genetic risk factor p
Externí odkaz:
https://doaj.org/article/00e3ef22c51b4762863b27a5f510cabb
Autor:
Marisol Herrera-Rivero, Mazda Adli, Kazufumi Akiyama, Nirmala Akula, Azmeraw T. Amare, Raffaella Ardau, Bárbara Arias, Jean-Michel Aubry, Lena Backlund, Frank Bellivier, Antonio Benabarre, Susanne Bengesser, Abesh Kumar Bhattacharjee, Joanna M. Biernacka, Armin Birner, Micah Cearns, Pablo Cervantes, Hsi-Chung Chen, Caterina Chillotti, Sven Cichon, Scott R. Clark, Francesc Colom, Cristiana Cruceanu, Piotr M. Czerski, Nina Dalkner, Franziska Degenhardt, Maria Del Zompo, J. Raymond DePaulo, Bruno Etain, Peter Falkai, Ewa Ferensztajn-Rochowiak, Andreas J. Forstner, Josef Frank, Louise Frisén, Mark A. Frye, Janice M. Fullerton, Carla Gallo, Sébastien Gard, Julie S. Garnham, Fernando S. Goes, Maria Grigoroiu-Serbanescu, Paul Grof, Ryota Hashimoto, Roland Hasler, Joanna Hauser, Urs Heilbronner, Stefan Herms, Per Hoffmann, Liping Hou, Yi-Hsiang Hsu, Stephane Jamain, Esther Jiménez, Jean-Pierre Kahn, Layla Kassem, Tadafumi Kato, John Kelsoe, Sarah Kittel-Schneider, Po-Hsiu Kuo, Ichiro Kusumi, Barbara König, Gonzalo Laje, Mikael Landén, Catharina Lavebratt, Marion Leboyer, Susan G. Leckband, Mario Maj, Mirko Manchia, Cynthia Marie-Claire, Lina Martinsson, Michael J. McCarthy, Susan L. McElroy, Vincent Millischer, Marina Mitjans, Francis M. Mondimore, Palmiero Monteleone, Caroline M. Nievergelt, Tomas Novák, Markus M. Nöthen, Claire O’Donovan, Norio Ozaki, Sergi Papiol, Andrea Pfennig, Claudia Pisanu, James B. Potash, Andreas Reif, Eva Reininghaus, Hélène Richard-Lepouriel, Gloria Roberts, Guy A. Rouleau, Janusz K. Rybakowski, Martin Schalling, Peter R. Schofield, Klaus Oliver Schubert, Eva C. Schulte, Barbara W. Schweizer, Giovanni Severino, Tatyana Shekhtman, Paul D. Shilling, Katzutaka Shimoda, Christian Simhandl, Claire M. Slaney, Alessio Squassina, Thomas Stamm, Pavla Stopkova, Fabian Streit, Fasil Tekola-Ayele, Anbupalam Thalamuthu, Alfonso Tortorella, Gustavo Turecki, Julia Veeh, Eduard Vieta, Biju Viswanath, Stephanie H. Witt, Peter P. Zandi, Martin Alda, Michael Bauer, Francis J. McMahon, Philip B. Mitchell, Marcella Rietschel, Thomas G. Schulze, Bernhard T. Baune
Publikováno v:
International Journal of Bipolar Disorders, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Background Lithium (Li) remains the treatment of choice for bipolar disorders (BP). Its mood-stabilizing effects help reduce the long-term burden of mania, depression and suicide risk in patients with BP. It also has been shown to have benef
Externí odkaz:
https://doaj.org/article/d190709c270e4808ba3f01e9fa533547
Autor:
Anna H. Ou, Sara B. Rosenthal, Mazda Adli, Kazufumi Akiyama, Nirmala Akula, Martin Alda, Azmeraw T. Amare, Raffaella Ardau, Bárbara Arias, Jean-Michel Aubry, Lena Backlund, Michael Bauer, Bernhard T. Baune, Frank Bellivier, Antonio Benabarre, Susanne Bengesser, Abesh Kumar Bhattacharjee, Joanna M. Biernacka, Pablo Cervantes, Guo-Bo Chen, Hsi-Chung Chen, Caterina Chillotti, Sven Cichon, Scott R. Clark, Francesc Colom, David A. Cousins, Cristiana Cruceanu, Piotr M. Czerski, Clarissa R. Dantas, Alexandre Dayer, Maria Del Zompo, Franziska Degenhardt, J. Raymond DePaulo, Bruno Étain, Peter Falkai, Frederike Tabea Fellendorf, Ewa Ferensztajn-Rochowiak, Andreas J. Forstner, Louise Frisén, Mark A. Frye, Janice M. Fullerton, Sébastien Gard, Julie S. Garnham, Fernando S. Goes, Maria Grigoroiu-Serbanescu, Paul Grof, Oliver Gruber, Ryota Hashimoto, Joanna Hauser, Urs Heilbronner, Stefan Herms, Per Hoffmann, Andrea Hofmann, Liping Hou, Stephane Jamain, Esther Jiménez, Jean-Pierre Kahn, Layla Kassem, Tadafumi Kato, Sarah Kittel-Schneider, Barbara König, Po-Hsiu Kuo, Ichiro Kusumi, Nina Lackner, Gonzalo Laje, Mikael Landén, Catharina Lavebratt, Marion Leboyer, Susan G. Leckband, Carlos A. López Jaramillo, Glenda MacQueen, Mario Maj, Mirko Manchia, Cynthia Marie-Claire, Lina Martinsson, Manuel Mattheisen, Michael J. McCarthy, Susan L. McElroy, Francis J. McMahon, Philip B. Mitchell, Marina Mitjans, Francis M. Mondimore, Palmiero Monteleone, Caroline M. Nievergelt, Markus M. Nöthen, Tomas Novák, Urban Ösby, Norio Ozaki, Sergi Papiol, Roy H. Perlis, Claudia Pisanu, James B. Potash, Andrea Pfennig, Daniela Reich-Erkelenz, Andreas Reif, Eva Z. Reininghaus, Marcella Rietschel, Guy A. Rouleau, Janusz K. Rybakowski, Martin Schalling, Peter R. Schofield, K. Oliver Schubert, Thomas G. Schulze, Barbara W. Schweizer, Florian Seemüller, Giovanni Severino, Tatyana Shekhtman, Paul D. Shilling, Kazutaka Shimoda, Christian Simhandl, Claire M. Slaney, Alessio Squassina, Thomas Stamm, Pavla Stopkova, Sarah K. Tighe, Alfonso Tortorella, Gustavo Turecki, Eduard Vieta, Julia Volkert, Stephanie Witt, Naomi R. Wray, Adam Wright, L. Trevor Young, Peter P. Zandi, John R. Kelsoe
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study of the Pharmacogenomics of Bipo
Externí odkaz:
https://doaj.org/article/4ffae4e761e24f54b9836464e5e374c0
Autor:
Ester Sada-Fuente, Selena Aranda, Sergi Papiol, Urs Heilbronner, María Dolores Moltó, Eduardo J. Aguilar, Javier González-Peñas, Álvaro Andreu-Bernabeu, Celso Arango, Benedicto Crespo-Facorro, Ana González-Pinto, Lourdes Fañanás, Barbara Arias, Julio Bobes, Javier Costas, Lourdes Martorell, Thomas G. Schulze, Janos L. Kalman, Elisabet Vilella, Gerard Muntané
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Schizophrenia (SCZ) is a complex disorder that typically arises in late adolescence or early adulthood. Age at onset (AAO) of SCZ is associated with long-term outcomes of the disease. We explored the genetic architecture of AAO with a genome
Externí odkaz:
https://doaj.org/article/79165bf273b64d24b7788777a2d08f5e
Autor:
Fanny Senner, Lena Hiendl, Susanne Bengesser, Kristina Adorjan, Ion-George Anghelescu, Bernhardt T. Baune, Monika Budde, Udo Dannlowski, Detlef E. Dietrich, Peter Falkai, Andreas J. Fallgatter, Alkomiet Hasan, Maria Heilbronner, Markus Jäger, Georg Juckel, Janos L. Kalman, Carsten Konrad, Mojtaba Oraki Kohshour, Sergi Papiol, Daniela Reich-Erkelenz, Jens Reimer, Sabrina K. Schaupp, Max Schmauß, Simon Senner, Carsten Spitzer, Thomas Vogl, Jörg Zimmermann, Urs Heilbronner, Eva C. Schulte, Thomas G. Schulze, Eva Z. Reininghaus, Sophie-Kathrin Kirchner, Nina Dalkner
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Existing guidelines recommend psychopharmacological treatment for the management of schizophrenia and bipolar disorder as part of holistic treatment concepts. About half of the patients do not take their medication regularly, although treatm
Externí odkaz:
https://doaj.org/article/fed399fc8cce403092c3ddc282f7c12f
Autor:
Teuntje A. D. Pelgrim, Alexandra Philipsen, Allan H. Young, Mario Juruena, Ester Jimenez, Eduard Vieta, Marin Jukić, Erik Van der Eycken, Urs Heilbronner, Ramona Moldovan, Martien J. H. Kas, Raj R. Jagesar, Markus M. Nöthen, Per Hoffmann, Noam Shomron, Laura L. Kilarski, Thérèse van Amelsvoort, Bea Campforts, The PSY-PGx Consortium, Roos van Westrhenen
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 151 (2024)
(1) Background Pharmacological treatment for psychiatric disorders has shown to only be effective in about one-third of patients, as it is associated with frequent treatment failure, often because of side effects, and a long process of trial-and-erro
Externí odkaz:
https://doaj.org/article/dc7bd9a9f3fa4fd4a6d128297d649d21
Autor:
Urs Heilbronner, Björn Albrecht
Publikováno v:
Frontiers in Human Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/9d3be7055fca47b784e384170d7e2b93
Autor:
Fanny Senner, Thomas Schneider-Axmann, Lalit Kaurani, Jörg Zimmermann, Jens Wiltfang, Martin von Hagen, Thomas Vogl, Carsten Spitzer, Simon Senner, Eva C. Schulte, Max Schmauß, Sabrina K. Schaupp, Jens Reimer, Daniela Reich-Erkelenz, Sergi Papiol, Mojtaba Oraki Kohshour, Fabian U. Lang, Carsten Konrad, Sophie-Kathrin Kirchner, Janos L. Kalman, Georg Juckel, Maria Heilbronner, Urs Heilbronner, Christian Figge, Ruth E. Eyl, Detlef Dietrich, Monika Budde, Ion-George Angelescu, Kristina Adorjan, Andrea Schmitt, Andre Fischer, Peter Falkai, Thomas G. Schulze
Publikováno v:
Schizophrenia Research: Cognition, Vol 32, Iss , Pp 100280- (2023)
As core symptoms of schizophrenia, cognitive deficits contribute substantially to poor outcomes. Early life stress (ELS) can negatively affect cognition in patients with schizophrenia and healthy controls, but the exact nature of the mediating factor
Externí odkaz:
https://doaj.org/article/a87a91e89a1743ffb00cde8a9c6b0527
Autor:
Mojtaba Oraki Kohshour, Nirmal R. Kannaiyan, August Jernbom Falk, Sergi Papiol, Urs Heilbronner, Monika Budde, Janos L. Kalman, Eva C. Schulte, Marcella Rietschel, Stephanie Witt, Andreas J. Forstner, Stefanie Heilmann-Heimbach, Markus M. Nöthen, Carsten Spitzer, Berend Malchow, Thorsten Müller, Jens Wiltfang, Peter Falkai, Andrea Schmitt, Moritz J. Rossner, Peter Nilsson, Thomas G. Schulze
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract The diagnostic criteria for schizophrenia (SCZ) and bipolar disorder (BD) are based on clinical assessments of symptoms. In this pilot study, we applied high-throughput antibody-based protein profiling to serum samples of healthy controls an
Externí odkaz:
https://doaj.org/article/316001b1b48848e78b45c2177c79da72
Autor:
Ester Sada-Fuente, Selena Aranda, Sergi Papiol, Urs Heilbronner, María Dolores Moltó, Eduardo J. Aguilar, Javier González-Peñas, Álvaro Andreu-Bernabeu, Celso Arango, Benedicto Crespo-Facorro, Ana González-Pinto, Lourdes Fañanás, Barbara Arias, Julio Bobes, Javier Costas, Lourdes Martorell, Thomas G. Schulze, Janos L. Kalman, Elisabet Vilella, Gerard Muntané
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/7a25b5e5e10247b98918a6f193887ca6