Zobrazeno 1 - 10
of 574
pro vyhledávání: '"Urothelial bladder cancer"'
Autor:
Yu Fan, Tao Dai, Dahong Zhang, Hongqian Guo, Fangjian Zhou, Benkang Shi, Shaogang Wang, Zhigang Ji, Chunxi Wang, Xudong Yao, Qiang Wei, Nanhui Chen, Jinchun Xing, Jinjian Yang, Chuize Kong, Jian Huang, Dingwei Ye, Liqun Zhou
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Data on prevalence of programmed death ligand-1 (PD-L1) expression and its correlation with tumor biomarkers in Chinese patients with muscle-invasive urothelial bladder cancer (MIUBC) are scarce. We investigated the prevalence of PD-L1 expre
Externí odkaz:
https://doaj.org/article/72a42ffa953e481b88559dbe7d08912f
Autor:
Dereje E. Bogale
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Bladder cancer is one of the most frequently occurring cancers worldwide. At diagnosis, 75% of urothelial bladder cancer cases have non-muscle invasive bladder cancer while 25% have muscle invasive or metastatic disease. Aberrantly activated
Externí odkaz:
https://doaj.org/article/0f39e133ecfe4951bd109a6ff367534c
Autor:
Konrad Bilski, Natalia Żeber-Lubecka, Maria Kulecka, Michalina Dąbrowska, Aneta Bałabas, Jerzy Ostrowski, Aleksandra Dobruch, Jakub Dobruch
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 3595-3609 (2024)
Sex-specific discrepancies in bladder cancer (BCa) are reported, and new studies imply that microbiome may partially explain the diversity. We aim to provide characterization of the bladder microbiome in both sexes diagnosed with non-muscle-invasive
Externí odkaz:
https://doaj.org/article/8b1581b5fac948da99bd9d47e7a64576
Autor:
Ding-ming Song, Tong Shen, Kun Feng, Yi-bo He, Shi-liang Chen, Yang Zhang, Wen-fei Luo, Lu Han, Ming Tong, Yanyang Jin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundBladder cancer, a highly fatal disease, poses a significant threat to patients. Positioned at 19q13.2-13.3, LIG1, one of the four DNA ligases in mammalian cells, is frequently deleted in tumour cells of diverse origins. Despite this, the pr
Externí odkaz:
https://doaj.org/article/80b4bd97051d4ecfbfe4b13beed374ed
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 7, Pp 1090-1096 (2023)
Objective To investigate the expression and clinical significance of silent information regulator 2 (SIRT2) form tissue of urothelial bladder cancer(UBC) and the effects of down-regulation of SIRT2 on the proliferation, invasion and migration of blad
Externí odkaz:
https://doaj.org/article/013824ddac1246b0a6274dab3d6b44f1
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundBladder cancer with high expression of human epidermal growth factor receptor-2 (HER2) is related to pathological malignancy and poor prognosis. The standard care for muscle-invasive urothelial bladder cancer (MIBC) is neoadjuvant chemother
Externí odkaz:
https://doaj.org/article/b1d1e06b841943e6a0e43118dba7fcf3
Autor:
Iliana K. Kerzeli, Alexandros Kostakis, Polat Türker, Per-Uno Malmström, Tammer Hemdan, Artur Mezheyeuski, Douglas G. Ward, Richard T. Bryan, Ulrika Segersten, Martin Lord, Sara M. Mangsbo
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Urothelial bladder cancer is most frequently diagnosed at the non-muscle-invasive stage (NMIBC). However, recurrences and interventions for intermediate and high-risk NMIBC patients impact the quality of life. Biomarkers for patie
Externí odkaz:
https://doaj.org/article/92d29f31336b4424a72603475b46d14c
Autor:
Elisabeth G. E. deVries, Josef Rüschoff, Martijn Lolkema, Josep Tabernero, Luca Gianni, Emile Voest, Derk Jan A. deGroot, Daniel Castellano, Gilles Erb, Julia Naab, Margarita Donica, Regula Deurloo, Michiel S. van derHeijden, Giuseppe Viale
Publikováno v:
Cancer Medicine, Vol 12, Iss 11, Pp 12071-12083 (2023)
Abstract The antibody‐drug conjugate trastuzumab emtansine (T‐DM1) is approved for human epidermal growth factor receptor 2 (HER2/ERBB2)–positive breast cancer. We aimed to study tumor HER2 expression and its effects on T‐DM1 responses in pat
Externí odkaz:
https://doaj.org/article/0f7c9c9a50584cb282318c9ac1965648
Autor:
Stefano Tappero, Paolo Dell'Oglio, Maria Angela Cerruto, Rafael Sanchez Salas, Oscar Buisan Rueda, Giuseppe Simone, Kees Hendricksen, Francesco Soria, Paolo Umari, Alessandro Antonelli, Alberto Briganti, Francesco Montorsi, Ottavio de Cobelli, Carlo Terrone, Antonio Galfano, Marco Moschini, Ettore Di Trapani
Publikováno v:
European Urology Open Science, Vol 50, Iss , Pp 47-56 (2023)
Background: Head-to-head comparisons between ileal conduit (IC) and orthotopic neobladder (ONB) in terms of peri- and postoperative outcomes and complications, in the specific setting of robot-assisted radical cystectomy (RARC), are not available. Ob
Externí odkaz:
https://doaj.org/article/0c68f0891469489e96f22b1f3d1b7170
Autor:
Slavica Stojnev, Irena Conic, Ana Ristic Petrovic, Ivan Petkovic, Milica Radic, Miljan Krstic, Ljubinka Jankovic Velickovic
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1123 (2024)
Death receptor signalization that triggers the extrinsic apoptotic pathway and TGF-β1 have important roles in urothelial carcinogenesis, with a complex interplay between them. The aim of this research was to assess the association of death receptors
Externí odkaz:
https://doaj.org/article/368140d02c9d459eb9329e45d6f79ebb