Differential protease expression by cutaneous squamous and basal cell carcinomas

Autor: Jean-Hilaire Saurat, Jean-Dominique Vassalli, Joachim Huarte, S Hirschel-Scholz, André-Pascal Sappino, Dominique Belin

Publikováno v: Journal of Clinical Investigation, Vol. 88, No 4 (1991) pp. 1073-1079

To assess the postulated role of plasminogen activation in tumor invasion, we have investigated the cellular sites of synthesis for urokinase-type (uPA) and tissue-type (tPA) plasminogen activators and their inhibitors (PAI-1 and PAI-2) in two human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026d2072df1d45692b1af2018bb0da71
https://doi.org/10.1172/jci115406

Expression of plasminogen activator inhibitors 1 and 2 in lung cancer and their role in tumor progression

Autor: Robert C, Isabelle Bolon, Gazzeri S, Veyrenc S, Brambilla C, Brambilla E

Publikováno v: Clinical Cancer Research
Clinical Cancer Research, American Association for Cancer Research, 1999, 5 (8), pp.2094-102
Europe PubMed Central
Clinical Cancer Research, Vol. 5, No 8 (1999) pp. 2094-2102

International audience; The plasminogen activator cascade initiated by urokinase type plasminogen activator (u-PA) is involved in extracellular matrix degradation during the tumor invasion process. The plasminogen activator inhibitors 1 (PAI-1) and 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a6f032469f8823a62217a2ffd659c74a
https://hal.archives-ouvertes.fr/hal-02345625

Modulation of bovine microvascular endothelial cell proteolytic properties by inhibitors of angiogenesis

Autor: J. W. Wilks, Roberto Montesano, Michael S. Pepper, Lelio Orci, Jean-Dominique Vassalli, Lothar Schweigerer

Publikováno v: Journal of Cellular Biochemistry, Vol. 55, No 4 (1994) pp. 419-434

A tightly controlled increase in extracellular proteolysis, restricted both in time and space, is an important component of the angiogenic process, while anti-proteolysis is effective in inhibiting angiogenesis. By focussing on the plasminogen activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d906dfeac6b73b8c5e654b285a79438
https://archive-ouverte.unige.ch/unige:9246

Basic fibroblast growth factor induces angiogenesis in vitro

Autor: Roger Guillemin, Andrew Baird, Lelio Orci, Jean-Dominique Vassalli, Roberto Montesano

Publikováno v: Proceedings of the National Academy of Sciences, Vol. 83, No 19 (1986) pp. 7297-7301

Fibroblast growth factors (FGFs) are potent mitogens for vascular and capillary endothelial cells in vitro and can stimulate the formation of blood capillaries (angiogenesis) in vivo. A crucial event in this process is the invasion of the perivascula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60ded6dca6ba22952aa73cd801e816a
https://doi.org/10.1073/pnas.83.19.7297

Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors

Autor: Dominique Belin, Jean-Dominique Vassalli, S de Kossodo, Pierre Vassalli, Martine A. Collart

Publikováno v: Journal of Experimental Medicine, Vol. 164, No 6 (1986) pp. 2113-2118
The Journal of Experimental Medicine

Exposure of mouse resident and thioglycollate-elicited peritoneal macrophages to IFN-gamma leads to a marked increase in the TNF-alpha (tumor necrosis factor/cachectin), IL-1 and u-PA (urokinase-type plasminogen activator) mRNA levels. Nuclear run-on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cb049628278410b58c241515219b11
https://doi.org/10.1084/jem.164.6.2113