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Cancer Progression Gene Expression Profiling Identifies the Urokinase Plasminogen Activator Receptor as a Biomarker of Metastasis in Cutaneous Squamous Cell Carcinoma

Autor: Elahe Minaei, Simon A. Mueller, Bruce Ashford, Amarinder Singh Thind, Jenny Mitchell, Jay R. Perry, Benjamin Genenger, Jonathan R. Clark, Ruta Gupta, Marie Ranson

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Cutaneous squamous cell carcinoma (cSCC) of the head and neck region is the second most prevalent skin cancer, with metastases to regional lymph nodes occurring in 2%–5% of cases. To further our understanding of the molecular events characterizing

Externí odkaz: https://doaj.org/article/3fab7cd4a9ee461d85584ffcb91394a7

The Urokinase Plasminogen Activation System in Pancreatic Cancer: Prospective Diagnostic and Therapeutic Targets

Autor: Ashna A. Kumar, Benjamin J. Buckley, Marie Ranson

Publikováno v: Biomolecules, Vol 12, Iss 2, p 152 (2022)

Pancreatic cancer is a highly aggressive malignancy that features high recurrence rates and the poorest prognosis of all solid cancers. The urokinase plasminogen activation system (uPAS) is strongly implicated in the pathophysiology and clinical outc

Externí odkaz: https://doaj.org/article/cb3a6ece27454a24b820ae7b7892de1f

HO-1 Interactors Involved in the Colonization of the Bone Niche: Role of ANXA2 in Prostate Cancer Progression

Autor: Nicolás Anselmino, Juan Bizzotto, Pablo Sanchis, Sofia Lage-Vickers, Emiliano Ortiz, Pia Valacco, Alejandra Paez, Estefania Labanca, Roberto Meiss, Nora Navone, Javier Cotignola, Elba Vazquez, Geraldine Gueron

Publikováno v: Biomolecules, Vol 10, Iss 3, p 467 (2020)

Background: Prostate cancer (PCa) dissemination shows a tendency to develop in the bone, where heme oxygenase 1 (HO-1) plays a critical role in bone remodeling. Previously by LC/ESI-MSMS, we screened for HO-1 interacting proteins and identified annex

Externí odkaz: https://doaj.org/article/d823517b71734d97a786bf89f76fd299

HO-1 Interactors Involved in the Colonization of the Bone Niche: Role of ANXA2 in Prostate Cancer Progression

Autor: Emiliano Ortiz, Sofia Lage-Vickers, Roberto Meiss, Juan Bizzotto, Estefania Labanca, Javier Cotignola, Geraldine Gueron, Pablo Sanchis, Nicolás Anselmino, Alejandra Paez, Pia Valacco, Elba Vazquez, Nora M. Navone

Publikováno v: Biomolecules, Vol 10, Iss 3, p 467 (2020)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
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Biomolecules
Volume 10
Issue 3

Background: Prostate cancer (PCa) dissemination shows a tendency to develop in the bone, where heme oxygenase 1 (HO-1) plays a critical role in bone remodeling. Previously by LC/ESI-MSMS, we screened for HO-1 interacting proteins and identified annex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6023f4856ffa12d1f281574c12f388
https://www.mdpi.com/2218-273X/10/3/467