Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Urmimala Basu"'
Autor:
Byeong-Kwon Sohn, Urmimala Basu, Seung-Won Lee, Hayoon Cho, Jiayu Shen, Aishwarya Deshpande, Laura C. Johnson, Kalyan Das, Smita S. Patel, Hajin Kim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Conformational dynamics during the early stage of transcription is crucial to understanding the regulation of transcription efficiency and fidelity. Here the authors, by single-molecule fluorescence resonance energy transfer approaches, examine the c
Externí odkaz:
https://doaj.org/article/15aa138db4754d9ebf6ec6afbcf7ccc9
Autor:
Jeremy G Bird, Urmimala Basu, David Kuster, Aparna Ramachandran, Ewa Grudzien-Nogalska, Atif Towheed, Douglas C Wallace, Megerditch Kiledjian, Dmitry Temiakov, Smita S Patel, Richard H Ebright, Bryce E Nickels
Publikováno v:
eLife, Vol 7 (2018)
Bacterial and eukaryotic nuclear RNA polymerases (RNAPs) cap RNA with the oxidized and reduced forms of the metabolic effector nicotinamide adenine dinucleotide, NAD+ and NADH, using NAD+ and NADH as non-canonical initiating nucleotides for transcrip
Externí odkaz:
https://doaj.org/article/57aac7a5967f43ecb1ef76a3ed32e3c3
Autor:
Partha Basu, Anushree Samaddar, Srabani Mittal, Urmimala Basu, Simi Chatterjee, Jaydip Biswas
Publikováno v:
International Journal of Preventive Medicine, Vol 5, Iss 2, Pp 191-195 (2014)
Background: VIA is a simple, inexpensive test widely advocated for resource-limited settings. Major limitation of VIA is its low specificity. HPV DNA testing can be used to triage VIA-positive women if the facilities are available. The major concern
Externí odkaz:
https://doaj.org/article/882c1f56ea8241699ecdea5beca85abd
Publikováno v:
International Journal of Science and Technology Research Archive. 3:213-227
Introduction: The foramina transversaria (FT) is a cardinal feature of the Cervical Vertebra. It transmits the vertebral vascular bundle (vertebral artery, and veins) and the sympathetic plexus which accompanies the vessels. Variations in number, siz
Transcription initiation catalyzed by the RNA polymerase is a multistep process involving promoter binding, transcription bubble formation, abortive RNA synthesis, and transition into elongation following promoter escape. We report cryo-EM structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffc83741d70be2f851293a3118f94bc
https://doi.org/10.21203/rs.3.rs-2082128/v1
https://doi.org/10.21203/rs.3.rs-2082128/v1
Publikováno v:
The Journal of Biological Chemistry
Mitochondria are specialized compartments that produce requisite ATP to fuel cellular functions and serve as centers of metabolite processing, cellular signaling, and apoptosis. To accomplish these roles, mitochondria rely on the genetic information
Publikováno v:
J Biol Chem
The structurally homologous Mtf1 and TFB2M proteins serve as transcription initiation factors of mitochondrial RNA polymerases in Saccharomyces cerevisiae and humans, respectively. These transcription factors directly interact with the nontemplate st
Autor:
Urmimala Basu, Hajin Kim, Jiayu Shen, Laura Johnson, Kalyan Das, Seung-Won Lee, Aishwarya P. Deshpande, Hayoon Cho, Byeong Kwon Sohn, Smita S. Patel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Controlling efficiency and fidelity in the early stage of mitochondrial DNA transcription is crucial for regulating cellular energy metabolism. Conformational transitions of the transcription initiation complex must be central for such control, but h
The structurally homologous Mtf1 and TFB2M proteins serve as transcription initiation factors of theSaccharomyces cerevisiaeand human mitochondrial RNA polymerases, respectively. These transcription factors directly interact with the non-template str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3866616bfa04699c68484548fbec638
https://doi.org/10.1101/2020.03.06.980961
https://doi.org/10.1101/2020.03.06.980961
Autor:
Aishwarya P. Deshpande, Hajin Kim, Jiayu Shen, Smita S. Patel, Byeong-Kwon Sohn, Hayoon Cho, Seung-Won Lee, Urmimala Basu
Publikováno v:
Nucleic Acids Research
Mitochondrial RNA polymerases depend on initiation factors, such as TFB2M in humans and Mtf1 in yeast Saccharomyces cerevisiae, for promoter-specific transcription. These factors drive the melting of promoter DNA, but how they support RNA priming and