Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Urmi Bajpai"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The escalating antibiotic resistance in mycobacterial species poses a significant threat globally, necessitating an urgent need to find alternative solutions. Bacteriophage-derived endolysins, which facilitate phage progeny release by attack
Externí odkaz:
https://doaj.org/article/f2c7ed8b496847ea8624662cd7b43c92
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Antibiotics remain the frontline agents for treating deadly bacterial pathogens. However, the indiscriminate use of these valuable agents has led to an alarming rise in AMR. The antibiotic pipeline is insufficient to tackle the AMR threat, especially
Externí odkaz:
https://doaj.org/article/9caca9053f96454783b9ca13ab1d1dc2
Autor:
Vincent Hervin, Ritu Arora, Jyoti Rani, Srinivasan Ramchandran, Urmi Bajpai, Luigi A. Agrofoglio, Vincent Roy
Publikováno v:
Molecules, Vol 25, Iss 21, p 4953 (2020)
The synthesis of hitherto unknown 5′-deoxy-5′-(4-substituted-1,2,3-triazol-1-yl)-uridine and its evaluation, through an one-pot screening assay, against MurA-F enzymes involved in Mycobacterium tuberculosis (Mtb), are described. Starting from UDP
Externí odkaz:
https://doaj.org/article/d0aa62783f59472a9f3ed5b7f49b0394
Publikováno v:
JAC-Antimicrobial Resistance. 5
Background Urinary tract infections (UTIs) represent a major public health issue. Uropathogenic Escherichia coli (UPEC) is a pathogen implicated in the vast majority of UTIs. Although treatable, the rampant and indiscriminate use of antibiotics has l
Autor:
Jyoti, Rani, Anasuya, Bhargav, Surabhi, Seth, Malabika, Datta, Urmi, Bajpai, Srinivasan, Ramachandran
Publikováno v:
Journal of Biosciences. 47
In type 2 diabetes mellitus (T2DM) patients, chronic hyperglycemia and inflammation underlie susceptibility to tuberculosis (TB) and result in poor TB control. Here, an integrative pathway-based approach is used to investigate perturbed pathways in T
Autor:
Dakun Lai, Anasuya Bhargav, Jyoti Rani, Urmi Bajpai, Faez Iqbal Khan, Srinivasan Ramachandran
Publikováno v:
Journal of Biomolecular Structure & Dynamics
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a colossal loss to human health and lives and has deeply impacted socio-economic growth. Remarkable efforts have been made by the scientific community in containing the virus
Autor:
Inshad Ali Khan, Smriti Sharma, Deepika, Ram A. Vishwakarma, Diksha Raina, Harshita Tiwari, Saurabh Saran, Payare L. Sangwan, Urmi Bajpai, Praveen K. Chinthakindi, Kandasamy Eniyan, Farrah Gul Khan, Amit Nargotra
Publikováno v:
Applied Microbiology and Biotechnology. 105:3611-3623
Bacterial cell has always been an attractive target for anti-infective drug discovery. MurA (UDP-N-acetylglucosamine enolpyruvyl transferase) enzyme of Escherichia coli (E.coli) is crucial for peptidoglycan biosynthetic pathway, as it is involved in
Autor:
Urmi Bajpai, Srinivasan Ramachandran, Jyoti Rani, Inshad Ali Khan, Kandasamy Eniyan, Rahul Bhat
Publikováno v:
SLAS Discovery. 25:70-78
The rapid rise in the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis (Mtb) mandates the discovery of novel tuberculosis (TB) drugs. Mur enzymes, which are identified as essential prot
Publikováno v:
Annals of the symposium: vacines, biopharmaceuticals, in vitro diagnosis, management, other related themes.
Autor:
Ritam Das, Urmi Bajpai
Publikováno v:
Virus Research. 323:198957
Mycobacteriophages are viruses of Mycobacterium spp. with promising diagnostic and therapeutic potential. Phage genome exploration and characterization of their proteomes are essential to gaining a better understanding of their role in phage biology.