Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Urmas Arumäe"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a potent survival-promoting protein with neurorestorative effect for neurodegenerative diseases. Its mechanism of action, albeit poorly known, depends strongly on the CXXC motif (CKGC). He
Externí odkaz:
https://doaj.org/article/0cde5fcfcfe844e38ac0b2c8bd164c66
Autor:
Riitta Lindström, Päivi Lindholm, Jukka Kallijärvi, Li-Ying Yu, T Petteri Piepponen, Urmas Arumäe, Mart Saarma, Tapio I Heino
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73928 (2013)
Mammalian MANF and CDNF proteins are evolutionarily conserved neurotrophic factors that can protect and repair mammalian dopaminergic neurons in vivo. In Drosophila, the sole MANF protein (DmManf) is needed for the maintenance of dopaminergic neurite
Externí odkaz:
https://doaj.org/article/fae0dbf955c84901a94041a459c04856
Autor:
Urmas Arumäe
Publikováno v:
Business: Theory and Practice, Vol 11, Iss 1 (2010)
In this article, the author provides a cursory introduction of the idea to base the interpretation of the functional mechanisms of territorial communities on Kuhn’s treatment of the paradigms of scientific communities. According to the author’s i
Externí odkaz:
https://doaj.org/article/ba908b25cb034632a431cbaf20d2359d
Autor:
Urmas Arumäe, Arno Almann
Publikováno v:
Problems and Perspectives in Management, Vol 8, Iss 1 (2010)
Externí odkaz:
https://doaj.org/article/e8aca8bea6324b72abdf0693ea845966
Autor:
Usama Abo-Ramadan, Emmi Pakarinen, Brandon K. Harvey, Tseng Kuan-Yin, Urmas Arumäe, Päivi Lindholm, Congjun Zheng, Leevi Lehtonen, Olli-Pekka Smolander, Maria Lindahl, Kert Mätlik, Mikko Airavaara, Jenni E. Anttila
Publikováno v:
Science Advances
Delayed delivery of MANF to rat brain after ischemic stroke promotes functional recovery and recruits phagocytic immune cells.
Stroke is the most common cause of adult disability in developed countries, largely because spontaneous recovery is of
Stroke is the most common cause of adult disability in developed countries, largely because spontaneous recovery is of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5e45d3c237a8f0ea828eed4b613908
http://hdl.handle.net/10138/252780
http://hdl.handle.net/10138/252780
Publikováno v:
FEBS Letters. 589:3739-3748
Parkinson's disease (PD) is a progressive neurodegenerative disorder where dopamine (DA) neurons in the substantia nigra degenerate and die. Since no cure for PD exists, there is a need for disease-modifying drugs. Glial cell line-derived neurotrophi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44ce1583873e6eb4e809f7ebf840e82
https://doi.org/10.1016/j.febslet.2015.09.031
https://doi.org/10.1016/j.febslet.2015.09.031
Autor:
Maria Lindahl, A.S. Bienemann, Kert Mätlik, Eija Jokitalo, Jaan Palgi, Urmas Arumäe, Merja H. Voutilainen, Helena Vihinen, Sigrid Booms, Mikko Airavaara, Mart Saarma, Henri J. Huttunen
Publikováno v:
eNeuro
Cerebral dopamine neurotrophic factor (CDNF) protects the nigrostriatal dopaminergic (DA) neurons in rodent models of Parkinson’s disease and restores DA circuitry when delivered after these neurons have begun to degenerate. These DA neurons have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06397716637b3a8531bf421b893e7f8d
http://europepmc.org/articles/PMC5318544
http://europepmc.org/articles/PMC5318544
Publikováno v:
Journal of Neuroscience Research. 91:780-785
During embryonic development, neurons are first produced in excess, and final numbers are adjusted by apoptosis at later stages. Crucial to this end is the amount of target-derived growth factor available for the neurons. By this means, the target si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e864289a96844426361a87e892df2922
https://doi.org/10.1002/jnr.23188
https://doi.org/10.1002/jnr.23188
Autor:
Dan Lindholm, Hai Thi Do, Laura Korhonen, Urmas Arumäe, Isabel Mogollón, Dan Duc Pham, Jyrki P. Kukkonen, Céline Bruelle, Ove Eriksson
Nerve growth factor (NGF) influences the survival and differentiation of a specific population of neurons during development, but its role in non-neuronal cells has been less studied. We observed here that NGF and its pro-form, pro-NGF, are elevated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e04c2413b59738b9417f1522e944adb
https://europepmc.org/articles/PMC4865921/
https://europepmc.org/articles/PMC4865921/
Publikováno v:
Cellular and Molecular Life Sciences. 69:1903-1916
The secreted protease proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to low-density lipid (LDL) receptor family members LDLR, very low density lipoprotein receptor (VLDLR) and apolipoprotein receptor 2 (ApoER2), and promotes their degrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274be2193660e32b1d2930ad036863ff
https://doi.org/10.1007/s00018-012-0977-6
https://doi.org/10.1007/s00018-012-0977-6