Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Uris Ros"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10108 (2023)
Necroptosis is a recently discovered form of regulated cell death characterized by the disruption of plasma membrane integrity and the release of intracellular content. Mixed lineage kinase domain-like (MLKL) protein is the main player of this cell d
Externí odkaz:
https://doaj.org/article/f6eabbfe71764be388d8682e29e3d562
Autor:
Lohans Pedrera, Uris Ros, Maria Laura Fanani, María E. Lanio, Richard M. Epand, Ana J. García-Sáez, Carlos Álvarez
Publikováno v:
Toxins, Vol 15, Iss 1, p 80 (2023)
Actinoporins have emerged as archetypal α-pore-forming toxins (PFTs) that promote the formation of pores in membranes upon oligomerization and insertion of an α-helix pore-forming domain in the bilayer. These proteins have been used as active compo
Externí odkaz:
https://doaj.org/article/ff19e9367bf04d36ab79cb18104bfecc
Autor:
Katia Cosentino, Edward Hermann, Nicolai von Kügelgen, Joseph D. Unsay, Uris Ros, Ana J. García-Sáez
Publikováno v:
Toxins, Vol 13, Iss 9, p 669 (2021)
Equinatoxin II (EqtII) and Fragaceatoxin C (FraC) are pore-forming toxins (PFTs) from the actinoporin family that have enhanced membrane affinity in the presence of sphingomyelin (SM) and phase coexistence in the membrane. However, little is known ab
Externí odkaz:
https://doaj.org/article/137e32d22154401e8999f87bace83da8
Autor:
Carlos Alvarez, Carmen Soto, Sheila Cabezas, Javier Alvarado-Mesén, Rady Laborde, Fabiola Pazos, Uris Ros, Ana María Hernández, María Eliana Lanio
Publikováno v:
Toxins, Vol 13, Iss 8, p 567 (2021)
Actinoporins (APs) are soluble pore-forming proteins secreted by sea anemones that experience conformational changes originating in pores in the membranes that can lead to cell death. The processes involved in the binding and pore-formation of member
Externí odkaz:
https://doaj.org/article/60fc8ae93ecb4622836e15e1a451e966
Autor:
Uris Ros, Aida Peña-Blanco, Kay Hänggi, Ulrich Kunzendorf, Stefan Krautwald, W. Wei-Lynn Wong, Ana J. García-Sáez
Publikováno v:
Cell Reports, Vol 19, Iss 1, Pp 175-187 (2017)
Necroptosis is a form of regulated necrosis that results in cell death and content release after plasma membrane permeabilization. However, little is known about the molecular events responsible for the disruption of the plasma membrane. Here, we fin
Externí odkaz:
https://doaj.org/article/f772884ba0c946f4a0b83a88032db294
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2412 (2020)
Pyroptosis, necroptosis, and ferroptosis are well-characterized forms of regulated necrosis that have been associated with human diseases. During regulated necrosis, plasma membrane damage facilitates the movement of ions and molecules across the bil
Externí odkaz:
https://doaj.org/article/a25d8f3de9184c8195b83d4d7741f608
Autor:
Javier Alvarado, Yeney Álvarez, Lohans Pedrera, Uris Ros, María E Lanio, Aisel Valle, Carlos Álvarez
Publikováno v:
Biotecnología Aplicada, Vol 31, Iss 1, Pp 53-56
Actinoporins are highly hemolytic pore-forming proteins with a molecular mass of around 20 kDa and high affinity for sphingomyelin-containing membranes. On the crude extract of the sea anemone Anthopleura nigrescens, hemolytic activity (HA) was detec
Externí odkaz:
https://doaj.org/article/5e312501bcbe4c8f8d19267939c4eb58
Autor:
Uris Ros, Lohans Pedrera, Diana Martínez, Mayra Tejuca, Fabiola Pazos, Maria E Lanio, Carlos Alvarez
Publikováno v:
Biotecnología Aplicada, Vol 30, Iss 4, Pp 312-316
The Caribbean Sea anemone Stichodactyla helianthus produces two pore-forming proteins, sticholysins I and II (StI and StII). To clarify the contribution of the first thirty (StII) or thirty-one (StI) N-terminal amino acid residues to the activity of
Externí odkaz:
https://doaj.org/article/9c06ca0999244b0c9626f6b2901bd8e0
Autor:
Uris Ros, Stephan Hailfinger, Jenny Stroh, Silvia von Karstedt, Rafael A. Espiritu, Lohans Pedrera, Josephine Weber, Anja Schmitt, Ana J. García-Sáez
Publikováno v:
Cell Death & Differentiation. 28:1644-1657
Ferroptosis is an iron-dependent form of regulated necrosis associated with lipid peroxidation. Despite its key role in the inflammatory outcome of ferroptosis, little is known about the molecular events leading to the disruption of the plasma membra
Autor:
John S. H. Danial, Yuri Quintana, Uris Ros, Raed Shalaby, Eleonora G. Margheritis, Sabrina Chumpen Ramirez, Christian Ungermann, Ana J. Garcia-Saez, Katia Cosentino
Publikováno v:
The Journal of Physical Chemistry Letters
Analysis of single-molecule brightness allows subunit counting of high-order oligomeric biomolecular complexes. Although the theory behind the method has been extensively assessed, systematic analysis of the experimental conditions required to accura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd8ec81859c25596f42007552b7d1ee