Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Uridine Triacetate"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
5-fluorouracil (5FU) and capecitabine are fluoropyrimidine anti-neoplastic drugs commonly used in the treatment of different types of cancer. Hereditary dihydropyrimdine deaminase (DPD), thymidylate synthase mutations and drug overdose may lead to li
Externí odkaz:
https://doaj.org/article/2d586d8a4d184adc87f539cd753b5eb9
Akademický článek
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Autor:
Kimberley M. Zorn, Joseph L. Jilek, Xiaohong Zhang, Raymond K. Hau, Siennah R. Miller, Erin Q. Jennings, Sean Ekins, Daniel H. Foil, Nathan J. Cherrington, James J. Galligan, Stephen H. Wright
Publikováno v:
Mol Pharmacol
Equilibrative nucleoside transporters (ENTs) 1 and 2 facilitate nucleoside transport across the blood-testis barrier (BTB). Improving drug entry into the testes with drugs that use endogenous transport pathways may lead to more effective treatments f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9787db3cc85c03d7e5045ec556121646
https://doi.org/10.1124/molpharm.120.000169
https://doi.org/10.1124/molpharm.120.000169
Autor:
Saif MW
Publikováno v:
OncoTargets and Therapy, Vol Volume 13, Pp 10197-10206 (2020)
Muhammad Wasif Saif NorthwellHealth Cancer Institute, Donald and Barbara Zucker School of Medicine at Hofstra, Feinstein Institute for Medical Research, Lake Success, New York, NY, USACorrespondence: Muhammad Wasif SaifNorthwellHealth Cancer Institut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::fc1fd59362a0447ac69a20286e87b219
https://www.dovepress.com/alternative-treatment-options-in-patients-with-colorectal-cancer-who-e-peer-reviewed-article-OTT
https://www.dovepress.com/alternative-treatment-options-in-patients-with-colorectal-cancer-who-e-peer-reviewed-article-OTT
Publikováno v:
JACC. CardioOncology, Vol 2, Iss 2, Pp 329-332 (2020)
JACC: CardioOncology
JACC: CardioOncology
A 56-year-old woman with history of hypertension, inadequately controlled on hydrochlorothiazide and nebivolol, presented with colorectal cancer with metastases to the liver in 2019. Genotypic testing revealed that her colorectal cancer was KRAS/NRAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705dad0555579261252e3bbca771ef4f
http://www.sciencedirect.com/science/article/pii/S2666087320300727
http://www.sciencedirect.com/science/article/pii/S2666087320300727
Akademický článek
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Autor:
Konstantinos Laschos, George Nasioulas, Ariadni Angelaki, Dimitra Ioanna Lampropoulou, Sotirios Boumpoucheropoulos, Gerasimos Aravantinos, Eirini Papadopoulou, Vasilios Zidianakis, Anna-Lea Amylidi, Evgenia Nanou, Nikolaos Soupos, George Fildissis
Publikováno v:
Journal of Oncology Pharmacy Practice. 26:747-753
Fluoropyrimidine-based regimens are among the most commonly used chemotherapy combinations for the treatment of solid tumors. Several genetic polymorphisms that are implicated with fluoropyrimidine anabolism and catabolism have been associated with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45803591974edeaf184060cad87fa6d6
https://doi.org/10.1177/1078155219865597
https://doi.org/10.1177/1078155219865597
Autor:
Muhammad Wasif Saif
Publikováno v:
Expert Opinion on Orphan Drugs. 7:95-103
Introduction: In 2015, vistogard was approved both the US FDA and the European Medicines Agency (EMA) as an antidote in the treatment of 5-FU poisoning following an overdose of 5-FU or capecitabine or in patients exhibiting early-onset, severe or lif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ace0a51de0d323896b287d453f1d0d1e
https://doi.org/10.1080/21678707.2019.1591273
https://doi.org/10.1080/21678707.2019.1591273
Akademický článek
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Publikováno v:
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 26, Iss, Pp 100703-(2021)
Molecular Genetics and Metabolism Reports, Vol 26, Iss, Pp 100703-(2021)
Hereditary orotic aciduria (HOA) is a very rare inborn error of pyrimidine metabolism. It results from a defect of the uridine-5-monophosphate synthase (UMPS) gene. To date, only about twenty patients have been described. We report a case of HOA with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f02ddb6d865289be783d829c6e52c38
http://europepmc.org/articles/PMC7807243
http://europepmc.org/articles/PMC7807243