Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Uri Barenholz"'
Autor:
Elad Herz, Niv Antonovsky, Yinon Bar-On, Dan Davidi, Shmuel Gleizer, Noam Prywes, Lianet Noda-Garcia, Keren Lyn Frisch, Yehudit Zohar, David G. Wernick, Alon Savidor, Uri Barenholz, Ron Milo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
An E. coli strain able to use CO2 fixation for sugar synthesis was previously generated by experimental evolution of an engineered strain. Here, Herz et al. show that specific mutations in five genes, encoding carbon metabolism enzymes or key regulat
Externí odkaz:
https://doaj.org/article/690248970691410cad98d1f38c3b74f9
Publikováno v:
eLife, Vol 6 (2017)
A set of chemical reactions that require a metabolite to synthesize more of that metabolite is an autocatalytic cycle. Here, we show that most of the reactions in the core of central carbon metabolism are part of compact autocatalytic cycles. Such me
Externí odkaz:
https://doaj.org/article/4584bd0acbe34362a3a7a9be10a0390c
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153344 (2016)
Most proteins show changes in level across growth conditions. Many of these changes seem to be coordinated with the specific growth rate rather than the growth environment or the protein function. Although cellular growth rates, gene expression level
Externí odkaz:
https://doaj.org/article/19bcd2903a33471faa78bc4cede61e60
Autor:
Leeat Keren, Ora Zackay, Maya Lotan‐Pompan, Uri Barenholz, Erez Dekel, Vered Sasson, Guy Aidelberg, Anat Bren, Danny Zeevi, Adina Weinberger, Uri Alon, Ron Milo, Eran Segal
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp n/a-n/a (2013)
Most genes change expression levels across conditions, but it is unclear which of these changes represents specific regulation and what determines their quantitative degree. Here, we accurately measured activities of ∼900 S. cerevisiae and ∼1800
Externí odkaz:
https://doaj.org/article/a01ccda68c6b4e9192fdfc7cfc7d92f6
Autor:
Yehudit Zohar, Shmuel Gleizer, Ghil Jona, Dan Davidi, Tasneem Bareia, Ido Shani, Niv Antonovsky, Naama Tepper, Uri Barenholz, Arren Bar-Even, Ron Milo, Sergey Malitsky, Elad Noor, Elad Herz, Yinon M. Bar-On, Lior Zelcbuch, Shira Amram, David G. Wernick, Aryeh Wides
Publikováno v:
Cell
Summary Can a heterotrophic organism be evolved to synthesize biomass from CO2 directly? So far, non-native carbon fixation in which biomass precursors are synthesized solely from CO2 has remained an elusive grand challenge. Here, we demonstrate how
Autor:
Avi I. Flamholz, Miki Goldenfeld, Dan Davidi, Katja Tummler, Tomer Shlomi, Wolfram Liebermeister, Arren Bar-Even, Uri Barenholz, Elad Noor, Ron Milo
Publikováno v:
Proceedings of the National Academy of Sciences. 113:3401-3406
Significance The k cat values of enzymes are important for the study of metabolic systems. However, the current use of k cat presents major difficulties, as values for most enzymes have not been experimentally measured, and experimentally available v
Autor:
Shmuel Gleizer, Alon Savidor, Uri Barenholz, Ron Milo, Yinon M. Bar-On, Lianet Noda-García, Dan Davidi, David G. Wernick, Yehudit Zohar, Elad Herz, Keren Lyn Frisch, Noam Prywes, Niv Antonovsky
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Understanding the evolution of a new metabolic capability in full mechanistic detail is challenging, as causative mutations may be masked by non-essential "hitchhiking" mutations accumulated during the evolutionary trajectory. We have previously used
Autor:
Niv Antonovsky, Lior Zelcbuch, Elad Noor, Ron Milo, Tasneem Bareia, Uri Barenholz, Michal Dayagi, Ayelet Levin-Karp
Publikováno v:
ACS Synthetic Biology. 2:327-336
Translational coupling is the interdependence of translation efficiency of neighboring genes encoded within an operon. The degree of coupling may be quantified by measuring how the translation rate of a gene is modulated by the translation rate of it
Publikováno v:
eLife, 6
eLife
eLife, Vol 6 (2017)
eLife
eLife, Vol 6 (2017)
A set of chemical reactions that require a metabolite to synthesize more of that metabolite is an autocatalytic cycle. Here, we show that most of the reactions in the core of central carbon metabolism are part of compact autocatalytic cycles. Such me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6945f211edd4ce424ec6f0ee273581ee
https://doi.org/10.1101/074641
https://doi.org/10.1101/074641