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The effects of load on articular cartilage are complex. Dynamic loading of cartilage is associated with slight cell and tissue deformation as well as cyclical fluctuations in the hydrostatic pressure of cartilage and in fluid movement. Static loading
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https://ora.ox.ac.uk/objects/uuid:ee370f5a-e7c0-45a6-9d7c-aa560ef29879
https://ora.ox.ac.uk/objects/uuid:ee370f5a-e7c0-45a6-9d7c-aa560ef29879
We investigated the distribution of fibrillin-2 and LTBP-2 (latent TGF-β binding protein-2) in the intervertebral disc of the adult bovine tail. The association of fibrillin-2 and of LTBP-2 with fibrillin-1 was examined by dual immunofluorescence st
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https://ora.ox.ac.uk/objects/uuid:d883f627-c1d5-49f2-8bc4-90a55a5dec1a
https://ora.ox.ac.uk/objects/uuid:d883f627-c1d5-49f2-8bc4-90a55a5dec1a
By comparing results obtained in vivo on penetration of (35S) sulphate and (3H) methyl glucose into the intervertebral disc of adult dogs, with those calculated using Fick's law, and diffusion and partition coefficients obtained in vitro, diffusion w
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https://ora.ox.ac.uk/objects/uuid:a1bc2fe6-1051-4b21-9ad4-57b14cebb0bf
https://ora.ox.ac.uk/objects/uuid:a1bc2fe6-1051-4b21-9ad4-57b14cebb0bf
Autor:
Hopewell, B, Urban, JP
Articular chondrocytes are exposed to a unique osmotic environment, which varies throughout the depth of cartilage, and in response to mechanical loading or pathological conditions. In light of such osmotic variations we investigated the response of
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https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c5a0c83fbc42245e635548a9185f5d9d
https://ora.ox.ac.uk/objects/uuid:eb9bd9c7-2318-4fe3-8347-04ad0cd31c7b
https://ora.ox.ac.uk/objects/uuid:eb9bd9c7-2318-4fe3-8347-04ad0cd31c7b
The fluid content of the disc, which governs its mechanical response and biological behavior, varies with external load. Because load on the disc changes after death, the fluid content and swelling pressure profiles of human discs taken at autopsy we
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https://doi.org/10.1097/00007632-199204000-00006
https://doi.org/10.1097/00007632-199204000-00006
Autor:
Urban, JP
The focus of work on mechanotransduction in cartilage has changed markedly over the last 10 years. At the beginning of the decade, the interest lay in determining the net response of cartilage plugs, almost always as 35S-sulphate or 3H-proline incorp
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https://ora.ox.ac.uk/objects/uuid:7e6ad582-85d4-4c44-8be0-31092d2d8c6c
https://ora.ox.ac.uk/objects/uuid:7e6ad582-85d4-4c44-8be0-31092d2d8c6c
The intracellular milieu of chondroctyes is regulated by an array of proteins in the cell membrane which operate as transport pathways, allowing ions and nutrients such as glucose and amino acids and metabolites such as lactate to cross the plasma me
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https://ora.ox.ac.uk/objects/uuid:3a8bd895-cae1-4307-b9b8-5f308cc13eac
https://ora.ox.ac.uk/objects/uuid:3a8bd895-cae1-4307-b9b8-5f308cc13eac
Publikováno v:
Deutscher Kongress für Orthopädie und Unfallchirurgie; 70. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie, 92. Tagung der Deutschen Gesellschaft für Orthopädie und Orthopädische Chirurgie und 47. Tagung des Berufsverbandes der Fachärzte für Orthopädie; 20061002-20061006; Berlin; DOCE.2.2-609 /20060928/
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https://explore.openaire.eu/search/publication?articleId=od______1175::3535845891a23be8fe9356a8942e514d
http://www.egms.de/en/meetings/dgu2006/06dgu0070.shtml
http://www.egms.de/en/meetings/dgu2006/06dgu0070.shtml
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