Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Urban Höglund"'
Autor:
Sofia Appelberg, Gustaf Ahlén, Jingyi Yan, Negin Nikouyan, Sofie Weber, Olivia Larsson, Urban Höglund, Soo Aleman, Friedemann Weber, Emma Perlhamre, Johanna Apro, Eva‐Karin Gidlund, Ola Tuvesson, Simona Salati, Matteo Cadossi, Hanna Tegel, Sophia Hober, Lars Frelin, Ali Mirazimi, Matti Sällberg
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 10, Pp 1-11 (2022)
Abstract New variants in the SARS‐CoV‐2 pandemic are more contagious (Alpha/Delta), evade neutralizing antibodies (Beta), or both (Omicron). This poses a challenge in vaccine development according to WHO. We designed a more universal SARS‐CoV
Externí odkaz:
https://doaj.org/article/35ec9af66e3647f5894151746b9c3202
Autor:
Rüdiger Groß, Lívia Mesquita Dias Loiola, Leila Issmail, Nadja Uhlig, Valentina Eberlein, Carina Conzelmann, Lia‐Raluca Olari, Lena Rauch, Jan Lawrenz, Tatjana Weil, Janis A. Müller, Mateus Borba Cardoso, Andrea Gilg, Olivia Larsson, Urban Höglund, Sandra Axberg Pålsson, Anna Selch Tvilum, Kaja Borup Løvschall, Maria M. Kristensen, Anna‐Lena Spetz, Fortune Hontonnou, Marie Galloux, Thomas Grunwald, Alexander N. Zelikin, Jan Münch
Publikováno v:
Advanced Science, Vol 9, Iss 20, Pp n/a-n/a (2022)
Abstract Inhibitors of viral cell entry based on poly(styrene sulfonate) and its core–shell nanoformulations based on gold nanoparticles are investigated against a panel of viruses, including clinical isolates of SARS‐CoV‐2. Macromolecular inhi
Externí odkaz:
https://doaj.org/article/efb36e92da2449a5bac3fba657c93ca6
Autor:
Wael Bahnan, Sebastian Wrighton, Martin Sundwall, Anna Bläckberg, Olivia Larsson, Urban Höglund, Hamed Khakzad, Magdalena Godzwon, Maria Walle, Elisabeth Elder, Anna Söderlund Strand, Lotta Happonen, Oscar André, Johannes Kumra Ahnlide, Thomas Hellmark, Vidar Wendel-Hansen, Robert PA. Wallin, Johan Malmstöm, Lars Malmström, Mats Ohlin, Magnus Rasmussen, Pontus Nordenfelt
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Spike-specific antibodies are central to effective COVID19 immunity. Research efforts have focused on antibodies that neutralize the ACE2-Spike interaction but not on non-neutralizing antibodies. Antibody-dependent phagocytosis is an immune mechanism
Externí odkaz:
https://doaj.org/article/f92905abfadc4d269db7f2ae1d052963
Autor:
Pham-Tue-Hung Tran, Urban Höglund, Olivia Larsson, Sofia Appelberg, Ali Mirazimi, Magnus Johansson, Wessam Melik
Publikováno v:
Pathogens, Vol 11, Iss 2, p 233 (2022)
Removal of genes coding for major parts of capsid (C), premembrane (prM), and envelope (E) proteins on the flavivirus genome aborts the production of infectious virus particles where the remaining genome forms a replicon that retains replicability in
Externí odkaz:
https://doaj.org/article/4d896dff1f6c46319242a459b9fbf7aa
Autor:
Pham-Tue-Hung Tran, Naveed Asghar, Urban Höglund, Olivia Larsson, Lars Haag, Ali Mirazimi, Magnus Johansson, Wessam Melik
Publikováno v:
Microorganisms, Vol 8, Iss 12, p 1890 (2020)
Kunjin virus (KUNV) is an attenuated strain of the severe neurotropic West Nile virus (WNV). The virus has a single-strand positive-sense RNA genome that encodes a polyprotein. Following gene expression, the polyprotein is cleaved into structural pro
Externí odkaz:
https://doaj.org/article/377d46ced52b46f6931a998e21c821de
Autor:
Mårten Fryknäs, Rolf Larsson, Stig Linder, Peter Nygren, Mats Gustafsson, Urban Höglund, Ruben Isacson, Maria Hägg Olofsson, Xiaonan Zhang, Wojciech Senkowski
Supplementary materials, Tables S1-S2. Supplementary Table S1. List of the 12 3D-selective screening hits, Supplementary Table S2. Structures and properties of the five final hit compounds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40de9ecfce1f7bbce5f89799deb441e7
https://doi.org/10.1158/1535-7163.22501000.v1
https://doi.org/10.1158/1535-7163.22501000.v1
Autor:
Mårten Fryknäs, Rolf Larsson, Stig Linder, Peter Nygren, Mats Gustafsson, Urban Höglund, Ruben Isacson, Maria Hägg Olofsson, Xiaonan Zhang, Wojciech Senkowski
Supplementary Figures S1-S8. S1. Glucose concentration and pH in spheroid culture medium; S2. Dose-response and time-course experiment; S3. GFP-based and TOX8 assay comparison; S4. HT-29 spheroid-based clonogenic assay; S5. Final hit compounds' effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9466d9ab091164d34eb62f48b0c001be
https://doi.org/10.1158/1535-7163.22501003
https://doi.org/10.1158/1535-7163.22501003
Autor:
Mårten Fryknäs, Rolf Larsson, Stig Linder, Peter Nygren, Mats Gustafsson, Urban Höglund, Ruben Isacson, Maria Hägg Olofsson, Xiaonan Zhang, Wojciech Senkowski
Because dormant cancer cells in hypoxic and nutrient-deprived regions of solid tumors provide a major obstacle to treatment, compounds targeting those cells might have clinical benefits. Here, we describe a high-throughput drug screening approach, us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::752cab2a6f186791e5009bb665a145bd
https://doi.org/10.1158/1535-7163.c.6536653.v1
https://doi.org/10.1158/1535-7163.c.6536653.v1
Autor:
Melik, Pham-Tue-Hung Tran, Urban Höglund, Olivia Larsson, Sofia Appelberg, Ali Mirazimi, Magnus Johansson, Wessam
Publikováno v:
Pathogens; Volume 11; Issue 2; Pages: 233
Removal of genes coding for major parts of capsid (C), premembrane (prM), and envelope (E) proteins on the flavivirus genome aborts the production of infectious virus particles where the remaining genome forms a replicon that retains replicability in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::d096f3aff467ec04d8d99fa8db9e5909
Autor:
K. Sofia Appelberg, Gustaf Ahlen, Negin Nikoyan, Jingy Yan, Sofie Weber, Olivia Larsson, Urban Höglund, Soo Aleman, Friedemann Weber, Emma Perlhamre, Johanna Apro, Eva-Karin Gidlund, Ola Tuvesson, Matteo Cadossi, SImona Salati, Hanna Tegel, Sophia Hober, Lars Frelin, ali mirazimi, Matti Sallberg
The SARS-CoV-2 pandemic is constantly changing with new variants appearing that are more contagious (Alpha and Delta), evade the neutralising antibody (NAb) response (Beta), or both (Omicron). This is a challenge for vaccine development. We generated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ec32be007dd0ce5446fcaa27af0b37a
https://doi.org/10.21203/rs.3.rs-1276351/v1
https://doi.org/10.21203/rs.3.rs-1276351/v1