Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Urban, Novak"'
Autor:
Christian Messerli, Gertrud Wiedemann, Naomi Porret, Michael Nagler, Katja Seipel, Barbara Jeker, Urban Novak, Sacha Zeerleder, Ulrike Bacher, Thomas Pabst
Publikováno v:
Turkish Journal of Hematology, Vol 40, Iss 3, Pp 187-196 (2023)
Cytokine-release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) are significant complications in patients with relapsed/refractory diffuse large B-cell lymphoma undergoing chimeric antigen receptor T-cell (CAR-T cel
Externí odkaz:
https://doaj.org/article/9a24576f2c1a4135973771d15a06c133
Autor:
Philipp Berning, Evgenii Shumilov, Markus Maulhardt, Hristo Boyadzhiev, Andrea Kerkhoff, Simon Call, Christian Reicherts, Anna O. Saidy, Enver Aydilek, Michèle Hoffmann, Urban Novak, Michael Daskalakis, Norbert Schmitz, Matthias Stelljes, Gerald Wulf, Ulrike Bacher, Georg Lenz, Thomas Pabst
Publikováno v:
HemaSphere, Vol 8, Iss 3, Pp n/a-n/a (2024)
Abstract CD19‐directed chimeric antigen receptor (CAR)‐T cell therapy has become a standard treatment for relapsed/refractory diffuse large B‐cell lymphoma (r/r DLBCL). While the benefits of CAR‐T cell treatment are clear in the general patie
Externí odkaz:
https://doaj.org/article/05d6d035219c46dfa19febde67f0fda6
Autor:
Evgenii Shumilov, Hristo Boyadzhiev, Paolo Mazzeo, Dilara Akhoundova, Michael Daskalakis, Urban Novak, Georg Lenz, Ulrike Bacher, Thomas Pabst
Publikováno v:
HemaSphere, Vol 7, Iss 12, p e984 (2023)
Efficacy and toxicity of chimeric antigen receptor T (CAR-T) cell therapy in relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL) with central nervous system (CNS) involvement remain understudied. Here we analyzed the outcomes of CAR-T cel
Externí odkaz:
https://doaj.org/article/dd61a97c44e04c2291efceda7b5ad418
Autor:
Urban Novak, Martin Fehr, Sämi Schär, Martin Dreyling, Christian Schmidt, Enrico Derenzini, Thilo Zander, Georg Hess, Ulrich Mey, Simone Ferrero, Nicolas Mach, Carola Boccomini, Sebastian Böttcher, Michèle Voegeli, Anne Cairoli, Vanesa-Sindi Ivanova, Thomas Menter, Stefan Dirnhofer, Bernhard Scheibe, Sandra Gadient, Katrin Eckhardt, Emanuele Zucca, Christoph Driessen, Christoph Renner
Publikováno v:
EClinicalMedicine, Vol 64, Iss , Pp 102221- (2023)
Summary: Background: The Bruton's tyrosine kinase inhibitor ibrutinib and the proteasome inhibitor bortezomib have single-agent activity, non-overlapping toxicities, and regulatory approval in mantle cell lymphoma (MCL). In vitro, their combination p
Externí odkaz:
https://doaj.org/article/2a646da2dfa940a19c0def3d5335b73c
Autor:
Christoph Mamot, Andreas Wicki, Ursula Hasler-Strub, Salome Riniker, Qiyu Li, Lisa Holer, Daniela Bärtschi, Khalil Zaman, Roger von Moos, Konstantin J. Dedes, Laura A. Boos, Urban Novak, Alexandre Bodmer, Reto Ritschard, Ellen C. Obermann, Alexandar Tzankov, Christoph Ackermann, Véronique Membrez-Antonioli, Ursina Zürrer-Härdi, Clemens B. Caspar, Stefanie Deuster, Martin Senn, Ralph Winterhalder, Christoph Rochlitz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Advanced triple negative breast cancer (TNBC) is an aggressive, but initially chemo-sensitive disease. The prognosis is poor and more than three quarters of patients experience progression 12 months after the initiation of conventional first
Externí odkaz:
https://doaj.org/article/1eb3fffffd304a00942ffdd17ebd7e8a
Autor:
Olaf Penack, Christophe Peczynski, Christian Koenecke, Emmanuelle Polge, Robin Sanderson, Ibrahim Yakoub-Agha, Nathalie Fegueux, Michael Daskalakis, Matthew Collin, Peter Dreger, Nicolaus Kröger, Urs Schanz, Adrian Bloor, Arnold Ganser, Caroline Besley, Gerald G. Wulf, Urban Novak, Ivan Moiseev, Hélène Schoemans, Grzegorz W. Basak, Christian Chabannon, Anna Sureda, Bertram Glass, Zinaida Peric
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
We investigated ≥ grade 3 (CTC-AE) organ toxicities for commercial CD19 chimeric antigen receptor T cell (CAR-T cell) products in 492 patients (Axi-Cel; n = 315; Tisa-Cel; n = 177) with Large B-cell Lymphoma in the European Society for Blood and Ma
Externí odkaz:
https://doaj.org/article/d5f9a6ad12ff48e2b04afd5d77a7a7a5
Autor:
Tatiana Wojtovicova, Drahomir Aujesky, Stephan Jakob, Nicolas Bonadies, Hansjakob Furrer, Urban Novak, Thomas Pabst, Britta Maurer, Burkhard Möller, Roman Christian Abegglen, Aristomenis Exadaktylos, Annalisa Berzigotti, Yara Banz, Vera Ulrike Bacher, Sacha S. Zeerleder, Joerg C. Schefold, André Tichelli, Anne Angelillo-Scherrer, Alicia Rovó
Publikováno v:
HemaSphere, Vol 7, p e39708d4 (2023)
Externí odkaz:
https://doaj.org/article/c3ef9c390c7e453d9c3914d57ac38e31
Autor:
Ulrike Bacher, Stefanie von Matt, Yara Banz, Behrouz Mansouri Taleghani, Urban Novak, Thomas Pabst
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 15, Iss 1 (2023)
Introduction: Autologous stem cell transplantation (ASCT) following high-dose chemotherapy is applied for patients with relapsed/refractory (r/r) DLBCL. However, prognosis of relapsing DLBCL post-ASCT remained poor until the availability of CAR-T cel
Externí odkaz:
https://doaj.org/article/601b18a0eecb4fb3aca4d1502d36b86d
Autor:
Peter Dreger, Nathalie Fegueux, Urban Novak, Jakob R Passweg, Christian Chabannon, Arnold Ganser, Edouard Forcade, Rafael de la Cámara, Grzegorz W Basak, Christian Koenecke, Urs Schanz, Olaf Penack, Christophe Peczynski, Emmanuelle Polge, Andrea Kuhnl, Michael Daskalakis, Nicolaus Kröger, Caroline Besley, Adrian Bloor, Lucia López Corral, Ivan Moiseev, Hélène Schoemans, Anna Sureda, Dina Averbuch, Bertram Glass, Zinaida Peric
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
We investigated the incidence and outcome of anti-CD19 chimeric antigen receptor (CAR) T-cells-associated Common Terminology Criteria for Adverse Events (CTCAE) ≥grade 3 cytopenia. In the EBMT CAR-T registry, we identified 398 adult patients with l
Externí odkaz:
https://doaj.org/article/671c0329917e4b598b9bb0701331071d
Autor:
Evgenii Shumilov, Paolo Mazzeo, Martin S. Zinkernagel, Myriam Legros, Naomi Porret, Lorenz Romagna, Detlef Haase, Georg Lenz, Urban Novak, Yara Banz, Thomas Pabst, Ulrike Bacher
Publikováno v:
Current Oncology, Vol 29, Iss 2, Pp 766-776 (2022)
Background: Intraocular lymphoma (IOL) presents a real challenge in daily diagnostics. Cyto- and/or histopathology of vitreous body represent the diagnostic cornerstones. Yet, false negative results remain common. Therefore, we analyzed the diagnosti
Externí odkaz:
https://doaj.org/article/ddb345b0544b4e509dcd48373ac70191