Inducible nitric oxide synthase (iNOS) is necessary for GBP-mediated T. gondii restriction in murine macrophages via vacuole nitration and intravacuolar network collapse.

Autor: Zhao XY; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.; The Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Lempke SL; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.; The Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Urbán Arroyo JC; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.; The Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Yin B; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.; The Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Holness NK; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.; The Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Smiley J; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.; The Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Ewald SE; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.; The Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 25. Date of Electronic Publication: 2023 Jul 25.