Zobrazeno 1 - 10 of 13 838 pro vyhledávání: '"Urate oxidase"'
1
Akademický článek
Metal-ligand dual-site single-atom nanozyme mimicking urate oxidase with high substrates specificity.
Autor: Wang K; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Hong Q; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Zhu C; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Xu Y; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Li W; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Wang Y; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Chen W; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Gu X; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Chen X; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Fang Y; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Shen Y; Medical School, Southeast University, Nanjing, 210009, China. Yanfei.Shen@seu.edu.cn., Liu S; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China., Zhang Y; Jiangsu Engineering Research Center for Carbon-Rich Materials and Devices, Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research, School of Chemistry and Chemical Engineering, Nanjing, 211189, China. Yuanjian.Zhang@seu.edu.cn.; Department of Oncology, Zhongda Hospital, Southeast University, Nanjing, 210009, China. Yuanjian.Zhang@seu.edu.cn.
Publikováno v: Nature communications [Nat Commun] 2024 Jul 08; Vol. 15 (1), pp. 5705. Date of Electronic Publication: 2024 Jul 08.
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2
Akademický článek
In vivo study of newly developed albumin-conjugated urate oxidase for gout treatment.
Autor: Cho J; Research and Development, ProAbTech Co., Ltd, Seoul, 07807, Republic of Korea.; Department of Biotechnology and Bioengineering, Interdisciplinary Program for Bioenergy and Biomaterials, Chonnam National University, Gwangju, 61186, Republic of Korea., Yang B; Research and Development, ProAbTech Co., Ltd, Seoul, 07807, Republic of Korea., Lee JH; School of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea., Kim H; Research and Development, ProAbTech Co., Ltd, Seoul, 07807, Republic of Korea., Kim H; Research and Development, ProAbTech Co., Ltd, Seoul, 07807, Republic of Korea., Go EB; School of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea., Bak DH; Research and Development, ProAbTech Co., Ltd, Seoul, 07807, Republic of Korea., Park SJ; Research and Development, ProAbTech Co., Ltd, Seoul, 07807, Republic of Korea., Kwon I; Research and Development, ProAbTech Co., Ltd, Seoul, 07807, Republic of Korea.; School of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea., Choi JI; Department of Biotechnology and Bioengineering, Interdisciplinary Program for Bioenergy and Biomaterials, Chonnam National University, Gwangju, 61186, Republic of Korea., Lee K; Research and Development, ProAbTech Co., Ltd, Seoul, 07807, Republic of Korea. khee0326@proabtech.com.
Publikováno v: Arthritis research & therapy [Arthritis Res Ther] 2023 Dec 18; Vol. 25 (1), pp. 247. Date of Electronic Publication: 2023 Dec 18.
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3
Akademický článek
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4
Akademický článek
Exploring the impact of taurine on the biochemical properties of urate oxidase: response surface methodology and molecular dynamics simulation
Autor: Parisa Shahmoradipour, Maryam Zaboli, Masoud Torkzadeh-Mahani
Publikováno v: Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-20 (2024)
Abstract This paper investigates the impact of taurine as an additive on the structural and functional stability of urate oxidase. First, the effect of the processing parameters for the stabilization of Urate Oxidase (UOX) using taurine was examined
Externí odkaz: https://doaj.org/article/f560776a73024148b0da468ecb0ddef8
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5
Akademický článek
Randomized, Double-Blind, Placebo-Controlled, Phase I, Dose- Escalation Study to Evaluate the Tolerance, Pharmacokinetics, Pharmacodynamics and Immunogenicity of PEGylated Urate Oxidase for Injection in Healthy Adults and Hyperuricemia Volunteers: Study Protocol
Autor: Sun F, Wang C, Xu Y, Lin P, Cao Y, Zhang J, Li X, Jiang X, Fu Y
Publikováno v: Diabetes, Metabolic Syndrome and Obesity, Vol Volume 16, Pp 4263-4268 (2023)
Feifei Sun,1,* Chenjing Wang,1,* Yi Xu,1 Pingping Lin,1 Yaozhong Cao,2 Jiahui Zhang,3 Xin Li,1 Xin Jiang,1 Yao Fu,1 Yu Cao1 1Clinical Trials Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of Chin
Externí odkaz: https://doaj.org/article/4f1ab92eae29498584185b009eba2274
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6
Akademický článek
A stable liver-specific urate oxidase gene knockout hyperuricemia mouse model finds activated hepatic de novo purine biosynthesis and urate nephropathy.
Autor: Pang L; Institute of Metabolic Diseases, Qingdao University, Qingdao, China; Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, China., Liang N; CAS Key Laboratory of Nutrition, Metabolism, and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China, University of Chinese Academy of Sciences, Beijing, China., Li C; Institute of Metabolic Diseases, Qingdao University, Qingdao, China; Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, China., Merriman TR; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, AL, United States., Zhang H; Institute of Metabolic Diseases, Qingdao University, Qingdao, China., Yan F; Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, China., Sun W; Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, China., Li R; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Xue X; Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, China., Liu Z; Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, China., Wang C; Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, China., Cheng X; Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, China., Chen S; CAS Key Laboratory of Nutrition, Metabolism, and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China, University of Chinese Academy of Sciences, Beijing, China., Yin H; CAS Key Laboratory of Nutrition, Metabolism, and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China, University of Chinese Academy of Sciences, Beijing, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, China; Department of Biomedical Sciences, Jockey Club College of Veterinary Medicine and Medicine, State Key Laboratory of Marine Pollution (SKLMP), The Shenzhen Research Institute, City University of Hong Kong, Hong Kong, China. Electronic address: hyyin@sinh.ac.cn., Dalbeth N; Department of Medicine, University of Auckland, Auckland, New Zealand. Electronic address: n.dalbeth@auckland.ac.nz., Yuan X; Institute of Metabolic Diseases, Qingdao University, Qingdao, China; Shandong Provincial Key Laboratory of Metabolic Diseases, Qingdao Key Laboratory of Gout, the Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address: xyuan226@qdu.edu.cn.
Publikováno v: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Mar; Vol. 1870 (3), pp. 167009. Date of Electronic Publication: 2024 Jan 17.
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7
Akademický článek
In vivo study of newly developed albumin-conjugated urate oxidase for gout treatment
Autor: Jeonghaeng Cho, Byungseop Yang, Jae Hun Lee, Hyunwoo Kim, Hyeongseok Kim, Eun Byeol Go, Dong-ho Bak, Su Jin Park, Inchan Kwon, Jong-il Choi, Kyunghee Lee
Publikováno v: Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-11 (2023)
Abstract Background Exogenously providing engineered Uox with enhanced half-life is one of the important urate-lowering treatments for gout. The potential of PAT101, a recombinant human albumin (rHA)-conjugated variant, was evaluated and compared as
Externí odkaz: https://doaj.org/article/ac493dc4a51e4b37abab1ac829f0460f
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8
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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9
Akademický článek
Metal-ligand dual-site single-atom nanozyme mimicking urate oxidase with high substrates specificity
Autor: Kaiyuan Wang, Qing Hong, Caixia Zhu, Yuan Xu, Wang Li, Ying Wang, Wenhao Chen, Xiang Gu, Xinghua Chen, Yanfeng Fang, Yanfei Shen, Songqin Liu, Yuanjian Zhang
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract In nature, coenzyme-independent oxidases have evolved in selective catalysis using isolated substrate-binding pockets. Single-atom nanozymes (SAzymes), an emerging type of non-protein artificial enzymes, are promising to simulate enzyme acti
Externí odkaz: https://doaj.org/article/64d4ab6727da4b1992a536eef34c1189
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10
Akademický článek
鸭源产尿酸氧化酶 菌株的筛选及其降尿酸能力评估.
Autor: 叶胜强1,2, 麻燕明1,3, 杨 宇1, 童新红1, 李中心1, 钱运国1, 龚 萍1
Publikováno v: Feed Research. 2023, Vol. 46 Issue 19, p64-68. 5p.
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