Gammaherpesvirus infection triggers the formation of tRNA fragments from premature tRNAs.

Autor: Manning AC; Department of Biomolecular Engineering, Baskin School of Engineering, University of California, Santa Cruz, Santa Cruz, CA, 95064, USA., Bashir MM; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA., Jimenez AR; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA, 52242, USA., Upton HE; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Collins K; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Lowe TM; Department of Biomolecular Engineering, Baskin School of Engineering, University of California, Santa Cruz, Santa Cruz, CA, 95064, USA., Tucker JM; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 02. Date of Electronic Publication: 2024 May 02.

Nanopore molecular trajectories of a eukaryotic reverse transcriptase reveal a long-range RNA structure sensing mechanism.

Autor: Shaw A; Institute for Quantitative Biosciences, University of California, Berkeley, CA, 94720., Craig JM; Department of Physics, University of Washington, Seattle, WA, 98195., Amiri H; Institute for Quantitative Biosciences, University of California, Berkeley, CA, 94720.; Department of Molecular and Cell Biology, University of California, Berkeley, CA, 94720., Kim J; Institute for Quantitative Biosciences, University of California, Berkeley, CA, 94720.; Biophysics Graduate Group, University of California, Berkeley, CA, 94720.; Jason L. Choy Laboratory of Single-Molecule Biophysics, University of California, Berkeley, CA 94720., Upton HE; Department of Molecular and Cell Biology, University of California, Berkeley, CA, 94720.; Bakar Fellows Program, University of California, Berkeley, CA, 94720., Pimentel SC; Department of Molecular and Cell Biology, University of California, Berkeley, CA, 94720.; Present address: NYU Grossman School of Medicine 550 First Avenue New York, NY 10016., Huang JR; Department of Physics, University of Washington, Seattle, WA, 98195., Marqusee S; Institute for Quantitative Biosciences, University of California, Berkeley, CA, 94720.; Biophysics Graduate Group, University of California, Berkeley, CA, 94720.; Department of Molecular and Cell Biology, University of California, Berkeley, CA, 94720.; Department of Chemistry, University of California, Berkeley, CA 94720., Collins K; Institute for Quantitative Biosciences, University of California, Berkeley, CA, 94720.; Department of Molecular and Cell Biology, University of California, Berkeley, CA, 94720.; Bakar Fellows Program, University of California, Berkeley, CA, 94720., Gundlach JH; Department of Physics, University of Washington, Seattle, WA, 98195., Bustamante CJ; Institute for Quantitative Biosciences, University of California, Berkeley, CA, 94720.; Biophysics Graduate Group, University of California, Berkeley, CA, 94720.; Department of Molecular and Cell Biology, University of California, Berkeley, CA, 94720.; Jason L. Choy Laboratory of Single-Molecule Biophysics, University of California, Berkeley, CA 94720.; Department of Chemistry, University of California, Berkeley, CA 94720.; Department of Physics, University of California, Berkeley, CA 94720.; Kavli Energy Nanoscience Institute, University of California, Berkeley, CA 94720.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 01. Date of Electronic Publication: 2023 Nov 01.

Separable structural requirements for cDNA synthesis, nontemplated extension, and template jumping by a non-LTR retroelement reverse transcriptase.

Autor: Pimentel SC; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California, USA., Upton HE; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California, USA., Collins K; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California, USA. Electronic address: kcollins@berkeley.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2022 Mar; Vol. 298 (3), pp. 101624. Date of Electronic Publication: 2022 Jan 21.

Telomerase Mechanism of Telomere Synthesis.

Autor: Wu RA; Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202; email: rawu@berkeley.edu , hupton@berkeley.edu , jacob.vogan@berkeley.edu , kcollins@berkeley.edu., Upton HE; Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202; email: rawu@berkeley.edu , hupton@berkeley.edu , jacob.vogan@berkeley.edu , kcollins@berkeley.edu., Vogan JM; Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202; email: rawu@berkeley.edu , hupton@berkeley.edu , jacob.vogan@berkeley.edu , kcollins@berkeley.edu., Collins K; Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202; email: rawu@berkeley.edu , hupton@berkeley.edu , jacob.vogan@berkeley.edu , kcollins@berkeley.edu.

Publikováno v: Annual review of biochemistry [Annu Rev Biochem] 2017 Jun 20; Vol. 86, pp. 439-460. Date of Electronic Publication: 2017 Jan 30.

Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.

Autor: Jiang J; Department of Chemistry and Biochemistry, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA. Department of Microbiology, Immunology, and Molecular Genetics, UCLA, Los Angeles, CA 90095, USA. California Nanosystems Institute, UCLA, Los Angeles, CA 90095, USA., Chan H; Department of Chemistry and Biochemistry, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA., Cash DD; Department of Chemistry and Biochemistry, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA., Miracco EJ; Department of Chemistry and Biochemistry, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA., Ogorzalek Loo RR; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA., Upton HE; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Cascio D; Department of Chemistry and Biochemistry, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA. UCLA-U.S. Department of Energy (DOE) Institute of Genomics and Proteomics, UCLA, Los Angeles, CA 90095, USA., O'Brien Johnson R; Department of Chemistry and Biochemistry, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA., Collins K; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Loo JA; Department of Chemistry and Biochemistry, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA. Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA. UCLA-U.S. Department of Energy (DOE) Institute of Genomics and Proteomics, UCLA, Los Angeles, CA 90095, USA., Zhou ZH; Department of Microbiology, Immunology, and Molecular Genetics, UCLA, Los Angeles, CA 90095, USA. California Nanosystems Institute, UCLA, Los Angeles, CA 90095, USA., Feigon J; Department of Chemistry and Biochemistry, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA. California Nanosystems Institute, UCLA, Los Angeles, CA 90095, USA. UCLA-U.S. Department of Energy (DOE) Institute of Genomics and Proteomics, UCLA, Los Angeles, CA 90095, USA. feigon@mbi.ucla.edu.

Publikováno v: Science (New York, N.Y.) [Science] 2015 Oct 30; Vol. 350 (6260), pp. aab4070. Date of Electronic Publication: 2015 Oct 15.