A novel approach to design chimeric multi epitope vaccine against Leishmania exploiting infected host cell proteome

Autor: Sooram Banesh, Neharika Gupta, Chethireddy Vihadhar Reddy, Uppuladinne Mallikarjunachari, Nupoor Patil, Sonavane Uddhavesh, Prakash Saudagar

Publikováno v: Heliyon, Vol 10, Iss 10, Pp e31306- (2024)

Leishmaniasis is a major infectious disease having high mortality which could be attributed to lack of a suitable vaccine candidate. We propose a novel approach to design multiepitope vaccine to leishmaniasis exploiting specific membrane proteome fro

Externí odkaz: https://doaj.org/article/d459466101c24df782e8e9199298533c

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Drug repurposing studies targeting SARS-CoV-2: an ensemble docking approach on drug target 3C-like protease (3CL ^pro ).

Autor: Koulgi S; High-Performance Computing-Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchavati, Pashan, Pune, India., Jani V; High-Performance Computing-Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchavati, Pashan, Pune, India., Uppuladinne M; High-Performance Computing-Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchavati, Pashan, Pune, India., Sonavane U; High-Performance Computing-Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchavati, Pashan, Pune, India., Nath AK; High-Performance Computing-Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchavati, Pashan, Pune, India., Darbari H; High-Performance Computing-Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchavati, Pashan, Pune, India., Joshi R; High-Performance Computing-Medical and Bioinformatics Applications Group, Centre for Development of Advanced Computing (C-DAC), Panchavati, Pashan, Pune, India.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2021 Sep; Vol. 39 (15), pp. 5735-5755. Date of Electronic Publication: 2020 Jul 17.