Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Upendra Mahat"'
Autor:
Upendra Mahat, Bhavuk Garg, Chao-Yie Yang, Hrishikesh Mehta, Rabi Hanna, Heesun J. Rogers, Aron Flagg, Andrei I. Ivanov, Seth J. Corey
Publikováno v:
Blood Advances. 6:2581-2594
Neutrophils migrate into inflamed tissue, engage in phagocytosis, and clear pathogens or apoptotic cells. These processes require well-coordinated events involving the actin cytoskeleton. We describe a child with severe neutropenia and episodes of so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828f0b1d6593dc22bcf0bc9f30bfc9f8
https://doi.org/10.1182/bloodadvances.2021006398
https://doi.org/10.1182/bloodadvances.2021006398
Publikováno v:
Pediatric Hematology and Oncology. 38:658-662
Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) is an immune checkpoint, which downregulates T cell activation and T regulatory cell function. CTLA4 haploinsufficiency (CTLA4 HI) leads to T cel...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f87d04f11ede9721bb8967bbe7f349c4
https://doi.org/10.1080/08880018.2021.1906802
https://doi.org/10.1080/08880018.2021.1906802
Publikováno v:
Pediatric hematology and oncology. 38(7)
Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) is an immune checkpoint, which downregulates T cell activation and T regulatory cell function. CTLA4 haploinsufficiency (CTLA4 HI) leads to T cell hyperactivation, immunodeficiency and variable degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf4e141710d27d273e6b27d18ac3dd6f
https://pubmed.ncbi.nlm.nih.gov/33900894
https://pubmed.ncbi.nlm.nih.gov/33900894
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is an immune checkpoint, which downregulates T cell activation and T regulatory cell function. CTLA-4 haploinsufficiency (CTLA4 HI) leads to T cell hyperactivation, immune dysregulation, lymphoprol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c917376e226e6a0def5479a9d603687f
https://doi.org/10.22541/au.160331932.20989541/v1
https://doi.org/10.22541/au.160331932.20989541/v1
Publikováno v:
Pediatric hematology and oncology. 37(2)
Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) haploinsufficiency (HI) is an immune dysregulation disorder characterized by T lymphocyte hyperactivation, and generalized lymphoproliferative and autoimmune disorders. Patients with CTLA4 haploinsu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629131234a60c9d36accb50b8aff7513
https://pubmed.ncbi.nlm.nih.gov/31971458
https://pubmed.ncbi.nlm.nih.gov/31971458
Autor:
Seth J. Corey, Aron Flagg, Heesun J. Rogers, Upendra Mahat, Andrei I. Ivanov, Hrishikesh M Mehta, Bhavuk Garg, Chao Yie Yang
Publikováno v:
Blood. 138:434-434
Introduction: As critical effectors of innate immune response, neutrophils migrate from the vasculature into inflamed tissue, where they engage in phagocytosis and clearance of pathogens and apoptotic cells. Migration, phagocytosis, and granule relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca5184161a1813f82dbc5130804950aa
https://doi.org/10.1182/blood-2021-152781
https://doi.org/10.1182/blood-2021-152781
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 26(3)
Prolonged thrombocytopenia after hematopoietic stem cell transplantation (HSCT) is a strong risk factor for transplantation-related morbidity and mortality, and no standard treatment guideline exists. Thrombopoietin receptor agonists (TPO-RAs), eltro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4034bb59198f617b5a9042ae91ea85c
https://pubmed.ncbi.nlm.nih.gov/31830528
https://pubmed.ncbi.nlm.nih.gov/31830528
Publikováno v:
Pediatric bloodcancerREFERENCES. 66(11)
Complement activation plays an important role in the pathogenesis of atypical hemolytic uremic syndrome. Eculizumab is a monoclonal antibody that blocks complement activity and has been approved for use in the treatment of atypical hemolytic uremic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e6ea3923bcca84e2998252682c5c5d
https://pubmed.ncbi.nlm.nih.gov/31286658
https://pubmed.ncbi.nlm.nih.gov/31286658
Publikováno v:
Journal of pediatric and adolescent gynecology. 32(4)
Background Beckwith-Wiedemann syndrome (BWS) is the most common pediatric overgrowth syndrome. BWS has a broad phenotypic presentation along with an increased propensity to develop various embryonal tumors. There are very few reported cases of gonada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b5913f9548181f4d91efbe14963421
https://pubmed.ncbi.nlm.nih.gov/30981832
https://pubmed.ncbi.nlm.nih.gov/30981832
Publikováno v:
Progress in Pediatric Cardiology. 56:101190
Three stage cardiac reconstruction is a common surgical procedure performed in children with complex cyanotic congenital heart diseases (CCHD) such as hypoplastic left heart syndrome (HLHS) and related single ventricle physiology. The perioperative p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a032afd5adc7db8b20bd49e18b4ef654
https://doi.org/10.1016/j.ppedcard.2019.101190
https://doi.org/10.1016/j.ppedcard.2019.101190