Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Updesh Dixit"'
Autor:
Updesh Dixit, Savita Bhutoria, Xuhong Wu, Liming Qiu, Menachem Spira, Sheeba Mathew, Richard Harris, Lucas J. Adams, Sean Cahill, Rajiv Pathak, P. Rajesh Kumar, Minh Nguyen, Seetharama A. Acharya, Michael Brenowitz, Steven C. Almo, Xiaoqin Zou, Alasdair C. Steven, David Cowburn, Mark Girvin, Ganjam V. Kalpana
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
HIV-1 integrase (IN) binds the host factor INI1/SMARCB1, which is required at multiple stages of HIV-1 replication. Here, the authors show that the same IN residues are involved in INI1 and RNA binding and in influencing particle morphogenesis and su
Externí odkaz:
https://doaj.org/article/b8bafab2f92543e6a097c5d975bbcf2d
Autor:
Rajiv Pathak, Carolina Eliscovich, Ignacio Mena, Updesh Dixit, Adolfo García-Sastre, Robert H Singer, Ganjam V. Kalpana
Publikováno v:
bioRxiv
SARS-CoV-2 infection has caused a major global burden. Despite intensive research, the mechanism and dynamics of early viral replication are not completely understood including the kinetics of formation of plus stranded genomic and subgenomic RNAs (g
Autor:
Ganjam V. Kalpana, P. Rajesh Kumar, Steven C. Almo, Liming Qiu, Savita Bhutoria, Seetharama A. Acharya, Xiaoqin Zou, Sheeba Mathew, Lucas J. Adams, Richard Harris, Minh B. Nguyen, Updesh Dixit, Alasdair C. Steven, Xuhong Wu, Michael Brenowitz, Menachem Spira, Sean M. Cahill, Rajiv Pathak, Mark E. Girvin, David Cowburn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
INI1/SMARCB1 binds to HIV-1 integrase (IN) through its Rpt1 domain and exhibits multifaceted role in HIV-1 replication. Determining the NMR structure of INI1-Rpt1 and modeling its interaction with the IN-C-terminal domain (IN-CTD) reveal that INI1-Rp
Autor:
Updesh Dixit, L. Martins, Rajiv Pathak, Elisabeth Bock, A. La Porte, A. Spivac, C. Eliscovich, R. Singer, V. Planelles, Ganjam V. Kalpana
Publikováno v:
Journal of Virus Eradication, Vol 5, Iss, Pp 1-(2019)
Autor:
Thomas W. Comollo, Virendra N. Pandey, Ashutosh K. Pandey, Vladyslav Kholodovych, Updesh Dixit
Publikováno v:
Biochemistry. 56:3434-3442
The heterodimeric human immunodeficiency virus type 1 reverse transcriptase is composed of p66 and p51 subunits. While in the p51 subunit, the connection domain is tucked in the polymerase cleft; it is effectively displaced from the cleft of the cata
Publikováno v:
Virology. 500:35-49
We recently identified a cell-factor, ErbB3 binding protein 1 (Ebp-1), which specifically interacts with the viral RNA genome and modulates HCV replication and translation. Ebp1 has two isoforms, p48, and p42, that result from differential splicing.
Publikováno v:
Nucleic Acids Research
Persistent hepatitis C virus (HCV) infection leads to chronic hepatitis C (CHC), which often progresses to liver cirrhosis (LC) and hepatocellular carcinoma (HCC). The molecular mechanisms that establish CHC and cause its subsequent development into
Autor:
Matthew B. Neiditch, Sushil Kumar, Virendra N. Pandey, Zhihe Liu, Ashutosh K. Pandey, Updesh Dixit, Kenneth M. Klein
Publikováno v:
Journal of virology. 91(23)
Hepatitis C virus (HCV) is a leading cause of chronic hepatitis C (CHC), liver cirrhosis, and hepatocellular carcinoma (HCC). Immunohistochemistry of archived HCC tumors showed abundant FBP1 expression in HCC tumors with the CHC background. Oncomine
Autor:
Adam G. Sowalsky, Sushil Kumar, Raymond B. Birge, Peter Hornbeck, Leszek Kotula, Sajjad Hossain, Updesh Dixit, Yongzhang Liu, Weiming Zheng, Jing Li, Bin Lu
Publikováno v:
Oncotarget
// Sushil Kumar 1 , Bin Lu 2,3 , Updesh Dixit 1 , Sajjad Hossain 4 , Yongzhang Liu 2 , Jing Li 5 , Peter Hornbeck 5 , Weiming Zheng 6 , Adam G. Sowalsky 7 , Leszek Kotula 4 and Raymond B. Birge 1 1 Department of Microbiology, Biochemistry and Molecul
Autor:
Virendra N. Pandey, Matthew B. Neiditch, Zhihe Liu, Ashutosh K. Pandey, Updesh Dixit, Kenneth M. Klein, Sushil Kumar
Publikováno v:
Journal of Virology. 89:7905-7921
Hepatitis C virus (HCV) is a leading cause of chronic hepatitis C (CHC), liver cirrhosis, and hepatocellular carcinoma (HCC). Immunohistochemistry of archived HCC tumors showed abundant FBP1 expression in HCC tumors with the CHC background. Oncomine