Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Upasana Gala"'
Autor:
Xuejun Tian, Upasana Gala, Yongping Zhang, Weina Shang, Sonal Nagarkar Jaiswal, Alberto di Ronza, Manish Jaiswal, Shinya Yamamoto, Hector Sandoval, Lita Duraine, Marco Sardiello, Roy V Sillitoe, Kartik Venkatachalam, Hengyu Fan, Hugo J Bellen, Chao Tong
Publikováno v:
PLoS Biology, Vol 13, Iss 3, p e1002103 (2015)
Autophagy helps deliver sequestered intracellular cargo to lysosomes for proteolytic degradation and thereby maintains cellular homeostasis by preventing accumulation of toxic substances in cells. In a forward mosaic screen in Drosophila designed to
Externí odkaz:
https://doaj.org/article/b0069c4576aa4ba5bcc4ed8cca6037a1
Autor:
Hector Sandoval, Chao Tong, Jia Zhou, Xuefei Fang, Manish Jaiswal, Wei Liu, Upasana Gala, Xiuying Duan
Publikováno v:
Journal of Genetics and Genomics. 43:77-86
Autophagy is a central lysosomal degradation pathway required for maintaining cellular homeostasis and its dysfunction is associated with numerous human diseases. To identify players in autophagy, we tested ∼1200 chemically induced mutations on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf5eea914b230f8d171bd8f5c54ebca
https://doi.org/10.1016/j.jgg.2015.10.005
https://doi.org/10.1016/j.jgg.2015.10.005
Autor:
Joep de Ligt, Gabriela David, Tomasz Gambin, Cynthia J. Curry, Alexander T. Lin-Moore, Donna M. Muzny, Rui Chen, Wojciech Wiszniewski, Davut Pehlivan, Shalini N. Jhangiani, Samantha Penney, Hugo J. Bellen, Tamar Harel, Karen L. Schulze, Manish Jaiswal, Tongchao Li, Ying Wooi Wan, Lisenka E.L.M. Vissers, Ender Karaca, Eric Boerwinkle, Yesim Parman, Bo Xiong, Ke Zhang, Vafa Bayat, James R. Lupski, William B. Dobyns, Upasana Gala, Michael F. Wangler, Shinya Yamamoto, Nele A Haelterman, Rando Allikmets, Merve Sivaci, Hector Sandoval, Kuchuan Chen, Wu Lin Charng, Robin D. Clark, Esra Battaloglu, Nichole Link, Ghayda M. Mirzaa, Stephen H. Tsang, Zhandong Liu, Yajing Xie, Richard A. Gibbs
Publikováno v:
Cell, 159, 200-14
Cell, 159, 1, pp. 200-14
Cell, 159, 1, pp. 200-14
SummaryInvertebrate model systems are powerful tools for studying human disease owing to their genetic tractability and ease of screening. We conducted a mosaic genetic screen of lethal mutations on the Drosophila X chromosome to identify genes requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548ec6a1ebebc47b9c4a9b06e9deaa90
http://hdl.handle.net/2066/138721
http://hdl.handle.net/2066/138721
Autor:
Yongping Zhang, Kartik Venkatachalam, Hector Sandoval, Roy V. Sillitoe, Weina Shang, Sonal Nagarkar Jaiswal, Chao Tong, Marco Sardiello, Hugo J. Bellen, Upasana Gala, Lita Duraine, Xuejun Tian, Manish Jaiswal, Heng-Yu Fan, Shinya Yamamoto, Alberto di Ronza
Publikováno v:
PLoS Biology
PLoS Biology, Vol 13, Iss 3, p e1002103 (2015)
PLoS Biology, Vol 13, Iss 3, p e1002103 (2015)
Autophagy helps deliver sequestered intracellular cargo to lysosomes for proteolytic degradation and thereby maintains cellular homeostasis by preventing accumulation of toxic substances in cells. In a forward mosaic screen in Drosophila designed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8190e181eb14d33439c00c7fb7bce5c0
https://doi.org/10.1371/journal.pbio.1002103
https://doi.org/10.1371/journal.pbio.1002103